Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kurinji Pandiyan"'
Autor:
Jueng Soo You, Daniel D De Carvalho, Chao Dai, Minmin Liu, Kurinji Pandiyan, Xianghong J Zhou, Gangning Liang, Peter A Jones
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003459 (2013)
Nucleosome occupancy controls the accessibility of the transcription machinery to DNA regulatory regions and serves an instructive role for gene expression. Chromatin remodelers, such as the BAF complexes, are responsible for establishing nucleosome
Externí odkaz:
https://doaj.org/article/5be9013a76e04763b0542855a765ecb5
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75136 (2013)
Epigenetic gene silencing, mediated by aberrant promoter DNA hypermethylation and repressive histone modifications, is a hallmark of cancer. Although heritable, the dynamic nature and potential reversibility through pharmacological interventions make
Externí odkaz:
https://doaj.org/article/fe1abba862874a08bb12e331ff40cc0c
Autor:
Gangning Liang, Peter A. Jones, Daniel J. Weisenberger, Jessica Charlet, Kimberly D. Siegmund, Peter W. Nichols, Kurinji Pandiyan, Jueng Soo You, Justin J. Lin, Christopher E. Duymich, Sameer Chopra, Elinne Becket
Supplementary Figure 1. Quantitation and location of epigenetic changes in all 6 patient samples. Supplementary Figure 2. Significant accessibility changes between 6 patients. Supplementary Figure 3. Accessibility changes shared in at least two patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e616c0c7bbcb9922829b7c88df8662
https://doi.org/10.1158/0008-5472.22410345
https://doi.org/10.1158/0008-5472.22410345
Autor:
Gangning Liang, Peter A. Jones, Daniel J. Weisenberger, Jessica Charlet, Kimberly D. Siegmund, Peter W. Nichols, Kurinji Pandiyan, Jueng Soo You, Justin J. Lin, Christopher E. Duymich, Sameer Chopra, Elinne Becket
Alterations in chromatin accessibility independent of DNA methylation can affect cancer-related gene expression, but are often overlooked in conventional epigenomic profiling approaches. In this study, we describe a cost-effective and computationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23672a101f92c6566a08ca0fae299fcd
https://doi.org/10.1158/0008-5472.c.6507972
https://doi.org/10.1158/0008-5472.c.6507972
Autor:
Gangning Liang, Peter A. Jones, Daniel J. Weisenberger, Jessica Charlet, Kimberly D. Siegmund, Peter W. Nichols, Kurinji Pandiyan, Jueng Soo You, Justin J. Lin, Christopher E. Duymich, Sameer Chopra, Elinne Becket
Legend and description of Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af5f6469bbd7d431c8941e336408554
https://doi.org/10.1158/0008-5472.22410348
https://doi.org/10.1158/0008-5472.22410348
Autor:
Stephen B. Baylin, Linzhao Cheng, Helai P. Mohammad, Jonathan Yen, Leslie Cope, Kornel E. Schuebel, Elias Zambidis, Feyruz V. Rassool, Wim Van Criekinge, William Matsui, Wayne Yu, Brian Simons, Pedram Argani, Wei Zhang, Kimberly J. Briggs, Kurinji Pandiyan, Liang Liang, David M. Berman, Leander Van Neste, Prashant Mali, Joyce E. Ohm
Supplementary Table 3 from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8551e96e7f4d1042dfb8cc99637c8398
https://doi.org/10.1158/0008-5472.22384484.v1
https://doi.org/10.1158/0008-5472.22384484.v1
Autor:
Stephen B. Baylin, Linzhao Cheng, Helai P. Mohammad, Jonathan Yen, Leslie Cope, Kornel E. Schuebel, Elias Zambidis, Feyruz V. Rassool, Wim Van Criekinge, William Matsui, Wayne Yu, Brian Simons, Pedram Argani, Wei Zhang, Kimberly J. Briggs, Kurinji Pandiyan, Liang Liang, David M. Berman, Leander Van Neste, Prashant Mali, Joyce E. Ohm
Supplementary Figures 1-6, Table 1B, 2, 4-6 from Cancer-Related Epigenome Changes Associated with Reprogramming to Induced Pluripotent Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cbb73d16c0d01991ceced9a14511f1
https://doi.org/10.1158/0008-5472.22384490.v1
https://doi.org/10.1158/0008-5472.22384490.v1
Autor:
Peter A. Jones, Jung Woo Eun, Sung Kyung Choi, Gangning Liang, Xiaojing Yang, Kurinji Pandiyan, Suk Woo Nam, Jueng Soo You, Seong Hwi Hong
Publikováno v:
Oncotarget
// Sung Kyung Choi 1, * , Kurinji Pandiyan 2, 3, * , Jung Woo Eun 4 , Xiaojing Yang 2 , Seong Hwi Hong 1 , Suk Woo Nam 4 , Peter A. Jones 5 , Gangning Liang 2 and Jueng Soo You 1, 6 1 Department of Biochemistry, School of Medicine, Konkuk University,
Autor:
Peter W. Nichols, Christopher E. Duymich, Peter A. Jones, Elinne Becket, Yin-Wei Chang, Inderbir S. Gill, Gangning Liang, Kurinji Pandiyan
Publikováno v:
Cancer Research. 75:A1-05
Background: While many studies have uncovered genetic mutations that drive tumorigenesis, far fewer have described epigenetic changes, such as nucleosome positioning and DNA methylation, which lead to the development of cancer. Therefore, accurately
Autor:
Wayne Yu, Helai P. Mohammad, Jonathan Yen, Joyce E. Ohm, David M. Berman, Leslie Cope, Prashant Mali, Feyruz V. Rassool, Kimberly J. Briggs, Wei Zhang, Brian W. Simons, Kurinji Pandiyan, Liang Liang, William Matsui, Elias T. Zambidis, Leander Van Neste, Wim Van Criekinge, Stephen B. Baylin, Pedram Argani, Kornel E. Schuebel, Linzhao Cheng
Publikováno v:
Cancer Research. 70:7662-7673
The ability to induce pluripotent stem cells from committed, somatic human cells provides tremendous potential for regenerative medicine. However, there is a defined neoplastic potential inherent to such reprogramming that must be understood and may