Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies.

Autor: Kuriakose Gift S; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Wieczorek L; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Sanders-Buell E; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Zemil M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Molnar S; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Donofrio G; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Townsley S; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Chenine AL; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Bose M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Trinh HV; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Barrows BM; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Sriplienchan S; Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand., Kitsiripornchai S; Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand., Nitayapan S; Royal Thai Army, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand., Eller LA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Rao M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Ferrari G; Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Surgery, Duke University School of Medicine, Durham, North Carolina, USA., Michael NL; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Ake JA; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Krebs SJ; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Robb ML; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Tovanabutra S; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA., Polonis VR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.; Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.

Publikováno v: Journal of virology [J Virol] 2023 Feb 28; Vol. 97 (2), pp. e0163522. Date of Electronic Publication: 2023 Feb 07.

Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding.

Autor: Bai, Hongjun, Lewitus, Eric, Li, Yifan, Thomas, Paul V., Zemil, Michelle, Merbah, Mélanie, Peterson, Caroline E., Thuraisamy, Thujitha, Rees, Phyllis A., Hajduczki, Agnes, Dussupt, Vincent, Slike, Bonnie, Mendez-Rivera, Letzibeth, Schmid, Annika, Kavusak, Erin, Rao, Mekhala, Smith, Gabriel, Frey, Jessica, Sims, Alicea, Wieczorek, Lindsay

Publikováno v: Nature Communications; 5/9/2024, Vol. 15 Issue 1, p1-16, 16p