Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain.

Autor: Hopp SC; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.; Department of Pharmacology, University of Texas Health Science Center San Antonio., Rogers JG; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio., Smith S; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.; Department of Pharmacology, University of Texas Health Science Center San Antonio., Campos G; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.; Costa Rica Institute of Technology (TEC)., Miller H; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio., Barannikov S; Department of Pathology and Laboratory Science, University of Texas Health Science Center San Antonio., Kuri EG; Department of Pharmacology, University of Texas Health Science Center San Antonio., Wang H; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio., Han X; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.; Department of Medicine, University of Texas Health Science Center San Antonio., Bieniek KF; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center San Antonio.; Department of Pathology and Laboratory Science, University of Texas Health Science Center San Antonio., Weintraub ST; Department of Biochemistry & Structural Biology, University of Texas Health Science Center San Antonio., Palavicini JP; Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center San Antonio.; Department of Medicine, University of Texas Health Science Center San Antonio.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 08. Date of Electronic Publication: 2023 Dec 08.