Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kuppuswamy Arumugam"'
Publikováno v:
IUCrData, Vol 9, Iss 1, p x231083 (2024)
The molecular structure of the solvated title salt, (C21H25N2)2[Fe2(C14H10S2)4]·2C3H7NO reveals that the anion is situated on a crystallographic inversion center in the triclinic space group P\overline{1}. The title compound crystallizes utilizing a
Externí odkaz:
https://doaj.org/article/90eebd0f074e4556ab22ed2080ee1269
Publikováno v:
IUCrData, Vol 4, Iss 9, p x191268 (2019)
The solid-state structural analysis of the title compound [systematic name: 5,11-disulfanylidene-4,6,10,12-tetrakis(2,4,6-trimethylphenyl)-4,6,10,12-tetraazatricyclo[7.3.0.03,7]dodeca-1(9),3(7)-diene-2,8-dione], C44H44N4O2S2 [+solvent], reveals that
Externí odkaz:
https://doaj.org/article/cb27966cfa0f45f58709cb855e869a9f
Publikováno v:
IUCrData, Vol 4, Iss 7, p x191003 (2019)
The title compound, [Ag2(C2H3O2)2(C19H20N2)2] (2), was readily synthesized by treatment of 3-benzyl-1-(2,4,6-trimethylphenyl)imidazolium chloride with silver acetate. The solution structure of the complex was analyzed by NMR spectroscopy, while the s
Externí odkaz:
https://doaj.org/article/011999edca48491e9b2c45c189b90b61
Autor:
Kristen M. Rehl, Jayaraman Selvakumar, Don Hoang, Kuppuswamy Arumugam, Alemayehu A. Gorfe, Kwang-jin Cho
Publikováno v:
bioRxiv
Ras proteins are membrane-bound GTPases that regulate essential cellular processes at the plasma membrane (PM). Constitutively active mutations of K-Ras, one of the three Ras isoforms in mammalian cells, are frequently found in human cancers. Ferroce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690b2948ab472ea66b63f419fed1a220
https://doi.org/10.1101/2023.03.28.534499
https://doi.org/10.1101/2023.03.28.534499
Autor:
Garrett L. Reinhard, Selvakumar Jayaraman, Joshua W. Prybil, Jonathan F. Arambula, Kuppuswamy Arumugam
Publikováno v:
Dalton Trans
Unambiguous assignment of redox sites on ferrocene coupled N-heterocyclic carbene gold(I) complexes [(Fc-NHC)(2)Au(I)](+) is critical to gain a greater mechanistic understanding of their activity in a cellular environment. Such information can be gar
Autor:
Jayaraman Selvakumar, Esther Y. Maier, Kuppuswamy Arumugam, Vincent M. Lynch, Stephanie Hufnagel, Jonathan F. Arambula, Sajal Sen, Jennie E. DeVore, Jonathan L. Sessler, Zhengrong Cui, Isaiah Aguilar
Publikováno v:
J Am Chem Soc
Immunogenic cell death (ICD) is a way of reengaging the tumor-specific immune system. ICD can be induced by treatment with chemotherapeutics. However, only a limited number of drugs and other treatment modalities have been shown to elicit the biomark
Publikováno v:
Acta Crystallographica Section C Structural Chemistry. 75:462-468
Diffraction-quality single crystals of two gold(I) complexes, namely bis(1,3-dimesityl-4,5-naphthoquinoimidazol-2-ylidene)gold(I) chloride benzene monosolvate, [Au(C29H26N2O2)2]Cl·C6H6or [(NQMes)2Au]Cl·C6H6,2, and bis(1,3-dimesityl-4,5-naphthoquino
Publikováno v:
Journal of Molecular Structure. 1141:477-483
Heteroleptic bis(dithiolene)-phosphine iron and cobalt complexes [Fe(adt)2(PMe3)] (1) and [Co(adt)2(PMe3)] (2) (adt = para-anisyldithiolene) have been synthesized from corresponding bis(dithiolene) dimers [M2(adt)4]2 (M = Fe, Co) by reacting with exc
Autor:
Vinoth Sittaramane, Jonathan L. Sessler, J. Kocerha, B. Burney, David A. Grossie, Z. Patel, M. Miles, K, J, Sidoran, Kuppuswamy Arumugam, Paul J. Lascuna, Jonathan F. Arambula, Rebecca McCall
Publikováno v:
Chemical Science
Herein, we report a simple and rational approach to the design of a targeted therapy (i.e., complex 1) whose mechanism of action involves targeting a single cancer relevant pathway via two independent mechanisms.
To achieve a systems-based appro
To achieve a systems-based appro
Autor:
Yue Li, Sajal Sen, Jonathan L. Sessler, Vincent M. Lynch, Kuppuswamy Arumugam, Jonathan F. Arambula
Publikováno v:
Chemical communications (Cambridge, England). 55(71)
We report the synthesis of a novel hydroxyl-functionalised heteroleptic bis-NHC gold(I) complex that permits conjugation to various amines via carbamate bond formation. The resulting derivatives were studied in vitro using cell proliferation assays a