MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.

Autor: Abualrous ET; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany.; Department of Physics, Faculty of Science, Ain Shams University, Cairo, Egypt., Stolzenberg S; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany., Sticht J; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.; Core Facility BioSupraMol, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Wieczorek M; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Roske Y; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany., Günther M; Theoretische Systembiologie (B086), Deutsches Krebsforschungszentrum, Heidelberg, Germany., Dähn S; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Boesen BB; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Calvo MM; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Biese C; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Kuppler F; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Medina-García Á; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Álvaro-Benito M; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Höfer T; Theoretische Systembiologie (B086), Deutsches Krebsforschungszentrum, Heidelberg, Germany., Noé F; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany. frank.noe@fu-berlin.de.; Microsoft Research AI4Science, Berlin, Germany. frank.noe@fu-berlin.de.; Department of Physics, Freie Universität Berlin, Berlin, Germany. frank.noe@fu-berlin.de.; Department of Chemistry, Rice University, Houston, TX, USA. frank.noe@fu-berlin.de., Freund C; Protein Biochemistry, Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany. christian.freund@fu-berlin.de.

Publikováno v: Nature chemical biology [Nat Chem Biol] 2023 Oct; Vol. 19 (10), pp. 1196-1204. Date of Electronic Publication: 2023 May 04.

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