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Akademický článek

Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice.

Autor: Kuppers DA; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Linton J; Translational Science and Therapeutics Division, Program in Immunology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Ortiz Espinosa S; Translational Science and Therapeutics Division, Program in Immunology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., McKenna KM; Translational Science and Therapeutics Division, Program in Immunology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Rongvaux A; Translational Science and Therapeutics Division, Program in Immunology, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Immunology, University of Washington, Seattle, Washington, United States of America., Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Jun 28; Vol. 18 (6), pp. e0287052. Date of Electronic Publication: 2023 Jun 28 (Print Publication: 2023).

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Functional genomic analysis of adult and pediatric brain tumor isolates.

Autor: Hoellerbauer P; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA.; Molecular and Cellular Biology Program, University of Washington, Seattle, WA USA., Biery MC; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA USA.; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA, USA., Arora S; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Rao Y; Huck Institute for the Life Sciences, Pennsylvania State University, State College, PA, USA., Girard EJ; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Mitchell K; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Dighe P; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Kufeld M; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Kuppers DA; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Herman JA; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Holland EC; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA., Soroceanu L; California Pacific Medical Center Research Institute, San Francisco, CA 94107, USA., Vitanza NA; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA, USA., Olson JM; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA USA.; Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute, Seattle, WA, USA., Pritchard JR; Huck Institute for the Life Sciences, Pennsylvania State University, State College, PA, USA., Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA USA.; Molecular and Cellular Biology Program, University of Washington, Seattle, WA USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 06. Date of Electronic Publication: 2023 Jan 06.

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Akademický článek

N ⁶ -methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis.

Autor: Kuppers DA; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Arora S; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Lim Y; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Lim AR; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.; Molecular and Cellular Biology Program, University of Washington, Seattle, WA, 98195, USA., Carter LM; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Corrin PD; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Plaisier CL; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, 85281, USA., Basom R; Genomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Delrow JJ; Genomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Wang S; Princess Margaret Cancer Centre/University Health Network, Toronto, ON, Canada., Hansen He H; Princess Margaret Cancer Centre/University Health Network, Toronto, ON, Canada., Torok-Storb B; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Hsieh AC; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. ahsieh@fredhutch.org.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. ahsieh@fredhutch.org.; School of Medicine, University of Washington, Seattle, WA, 98195, USA. ahsieh@fredhutch.org., Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. paddison@fredhutch.org.

Publikováno v: Nature communications [Nat Commun] 2019 Oct 10; Vol. 10 (1), pp. 4596. Date of Electronic Publication: 2019 Oct 10.

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Akademický článek

Molecular determinants of response to high-dose androgen therapy in prostate cancer.

Autor: Nyquist MD; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Corella A; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Mohamad O; Faculty of Medicine, Benha University, Benha, Egypt., Coleman I; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Kaipainen A; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Kuppers DA; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Lucas JM; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Paddison PJ; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Plymate SR; Department of Medicine, University of Washington, Seattle, Washington, USA.; Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, USA., Nelson PS; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA., Mostaghel EA; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Medicine, University of Washington, Seattle, Washington, USA.; Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington, USA.

Publikováno v: JCI insight [JCI Insight] 2019 Oct 03; Vol. 4 (19). Date of Electronic Publication: 2019 Oct 03.

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Akademický článek

The miR-106a~363 ^Xpcl1 miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27 ^Kip1 cell cycle inhibitor.

Autor: Kuppers DA; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Schmitt TM; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Hwang HC; Phenopath Laboratories, Seattle, Washington, USA., Samraj L; University of Washington, Seattle, Washington, USA., Clurman BE; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Fero ML; University of New Mexico, Albuquerque, New Mexico, USA.

Publikováno v: Oncotarget [Oncotarget] 2017 Apr 07; Vol. 8 (31), pp. 50680-50691. Date of Electronic Publication: 2017 Apr 07 (Print Publication: 2017).

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