Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kuppareddi Balamurugan"'
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Little is known about the general biology of minisatellites. The purpose of this study is to examine repeat mutations from the D1S80 minisatellite locus by sequence analysis to elucidate the mutational process at this locus. This is a highly polymorp
Externí odkaz:
https://doaj.org/article/1b3ffebd41bd413aad0372339ac6341b
Autor:
Quentin Gauthier, Bruce McCord, Nicole Fernandez Tejero, George Duncan, Hussain Alghanim, Kuppareddi Balamurugan, Joana Antunes
Publikováno v:
Forensic Science International: Genetics Supplement Series. 7:485-487
In this paper, four different applications are presented in forensic epigenetics using bisulfite modified PCR, HRM, and pyrosequencing. The first application involves the development of a multiplex amplification capable of simultaneous analysis of 4
Publikováno v:
Analytical biochemistry. 611
Discrimination of body fluids can provide important information in the investigation of crime scenes. The goal of this project was to identify new sets of tissue specific differentially methylated regions (tDMRs) and develop assays that can be utiliz
Autor:
Deborah S.B.S. Silva, Hussain Alghanim, Kuppareddi Balamurugan, Clarice Sampaio Alho, Bruce McCord, Joana Antunes
Publikováno v:
Forensic Science International: Genetics. 31:81-88
Recent developments in the analysis of epigenetic DNA methylation patterns have demonstrated that certain genetic loci show a linear correlation with chronological age. It is the goal of this study to identify a new set of epigenetic methylation mark
Autor:
George Duncan, Joana Antunes, Clarice Sampaio Alho, Bruce McCord, Deborah S.B.S. Silva, Kuppareddi Balamurugan
Publikováno v:
ELECTROPHORESIS. 37:2751-2758
The accurate identification of body fluids from crime scenes can aid in the discrimination between criminal and innocent intent. This research aimed to determine if the levels of DNA methylation in the locus PFN3A could be used to discriminate vagina
Autor:
Deborah S.B.S. Silva, Kuppareddi Balamurugan, Clarice Sampaio Alho, Bruce McCord, George Duncan, Joana Antunes
Publikováno v:
ELECTROPHORESIS. 36:1775-1780
We present epigenetic methylation data for two genetic loci, GRIA2, and NPTX2, which were tested for prediction of age from different donors of biofluids. We analyzed 44 saliva samples and 23 blood samples from volunteers with ages ranging from 5 to
Publikováno v:
ELECTROPHORESIS. 35:3020-3027
High-resolution melt (HRM) analysis of the VNTR region of the human D1S80 locus, a 16-bp repeat minisatellite from approximately 400 to over 700 bp in length, was investigated. A Qiagen Rotor-Gene Q using the Type-it PCR HRM kit was used to acquire H
Publikováno v:
ELECTROPHORESIS. 35:3079-3086
The focus of this study is to evaluate the application of epigenetic markers as a forensic tool for the determination of semen present in sexual assault cases. A series of genetic loci were screened in order to identify certain epigenetic markers dis
Autor:
Joana, Antunes, Deborah S B S, Silva, Kuppareddi, Balamurugan, George, Duncan, Clarice S, Alho, Bruce, McCord
Publikováno v:
Electrophoresis. 37(21)
The accurate identification of body fluids from crime scenes can aid in the discrimination between criminal and innocent intent. This research aimed to determine if the levels of DNA methylation in the locus PFN3A could be used to discriminate vagina
Publikováno v:
ELECTROPHORESIS. 33:1736-1745
The goal of this study is to explore the application of epigenetic markers in the identification of biofluids that are commonly found at the crime scene. A series of genetic loci were examined in order to define epigenetic markers that display differ