Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O -Acetyltransferase.

Autor: Kuplińska, Aleksandra¹ (AUTHOR) aleksandra.kuplinska@pg.edu.pl, Rząd, Kamila¹ (AUTHOR), Wojciechowski, Marek¹ (AUTHOR), Milewski, Sławomir¹ (AUTHOR), Gabriel, Iwona¹ (AUTHOR) iwona.gabriel@pg.edu.pl

Publikováno v: International Journal of Molecular Sciences. Jul2022, Vol. 23 Issue 14, p7763-7763. 19p.

Antifungal activity of L-homoserine O-acetyltransferase (CaMet2p) inhibitors

Autor: Gabriel, Iwona, Kuplińska, Aleksandra, Rząd, Kamila, Milewski, Sławomir

The dataset contains a set of optical densities at 600 nm measured at microplate reader to determine the rate of fungal growth in the presence of Candida albicans homoserine O-acetyltransferase inhibitors. Antifungal activities were determined agains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3b099df0bc2::93ef231a382b84b39bc9339d92712494

Identification and cloning of C. albicans SC5314 genes encoding L-methionine biosynthetic pathway enzymes

Autor: Gabriel, Iwona, Kuplińska, Aleksandra, Rząd, Kamila, Milewski, Sławomir

Enzymes of fungal L-methionine biosynthetic pathway: homoserine O-acetyltransferase (Met2p), O-acetylhomoserine sulfhydrylase (Met15p) and cystathionine-γ-synthase (Str2p) could be exploited as molecular targets for antifungal chemotherapy. The goal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=r3b099df0bc2::106b703e54368485db6f71b04d5bebab

Molecular targets for antifungals in amino acid and protein biosynthetic pathways.

Autor: Kuplińska, Aleksandra, Rząd, Kamila

Publikováno v: Amino Acids; Jul2021, Vol. 53 Issue 7, p961-991, 31p

Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity.

Autor: Rząd K; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland. kamila.rzad@pg.edu.pl., Gabriel I; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland., Paluszkiewicz E; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland., Kuplińska A; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland., Olszewski M; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland., Chylewska A; Department of Bioinorganic Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland., Dąbrowska AM; Department of Bioinorganic Chemistry, Faculty of Chemistry, University of Gdansk, Wita Stwosza 63, 80-308, Gdansk, Poland., Kozłowska-Tylingo K; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry and BioTechMed Center, Gdansk University of Technology, 11/12 Narutowicza Str., 80-233, Gdansk, Poland.

Publikováno v: Scientific reports [Sci Rep] 2024 Feb 13; Vol. 14 (1), pp. 3594. Date of Electronic Publication: 2024 Feb 13.