Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer.

Autor: Shea A; Institute of Cancer Research, London, United Kingdom., Eyal-Lubling Y; University of Cambridge, Cambridge, United Kingdom., Guerrero-Romero D; University of Cambridge, Cambridge, United Kingdom., Manzano Garcia R; University of Cambridge, Cambridge, United Kingdom., Greenwood W; University of Cambridge, Cambridge, United Kingdom., O'Reilly M; University of Cambridge, Cambridge, United Kingdom., Georgopoulou D; University of Cambridge, Cambridge, United Kingdom., Callari M; Michelangelo Foundation, Milan, Italy., Lerda G; University of Cambridge, Cambridge, United Kingdom., Wix S; University of Cambridge, Cambridge, United Kingdom., Giovannetti A; University of Cambridge, Cambridge, United Kingdom., Masina R; University of Cambridge, Cambridge, United Kingdom., Esmaeilishirazifard E; University of Cambridge, Cambridge, United Kingdom., Cope W; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Martin AG; University of Cambridge, Cambridge, United Kingdom., Nagano A; Queen Mary University of London, London, United Kingdom., Young L; University of Cambridge, Cambridge, United Kingdom., Kupczak S; Cancer Research UK Cambridge Center, Cambridgeshire, United Kingdom., Cheng Y; University of Cambridge, Cambridge, United Kingdom., Bardwell H; University of Cambridge, Cambridge, United Kingdom., Provenzano E; Cambridge University Hospitals NHS Foundation Trust, United Kingdom., Kane J; University of Cambridge, Cambridge, United Kingdom., Lay J; University of Cambridge, Cambridge, United Kingdom., Grybowicz L; Cambridge University Hospitals NHS Foundation Trust, United Kingdom., McAdam K; Cambridge University NHS Foundation Trust, United Kingdom., Caldas C; University of Cambridge, Cambridge, United Kingdom., Abraham J; University of Cambridge, Cambridge, United Kingdom., Rueda OM; University of Cambridge, Cambridge, United Kingdom., Bruna A; Institute of Cancer Research, London, United Kingdom.

Publikováno v: Cancer research [Cancer Res] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08.

MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.

Autor: Sodir NM; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Kortlever RM; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Barthet VJA; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Campos T; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Pellegrinet L; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Kupczak S; Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom., Anastasiou P; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Swigart LB; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California., Soucek L; Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain., Arends MJ; Division of Pathology, Cancer Research UK Edinburgh Centre, University of Edinburgh, Edinburgh, Scotland, United Kingdom., Littlewood TD; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom., Evan GI; Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom. gie20@cam.ac.uk.

Publikováno v: Cancer discovery [Cancer Discov] 2020 Apr; Vol. 10 (4), pp. 588-607. Date of Electronic Publication: 2020 Jan 15.

Inhibition of Bromodomain Proteins Enhances Oncolytic HAdVC5 Replication and Efficacy in Pancreatic Ductal Adenocarcinoma (PDAC) Models.

Autor: Miao, Tizong^1,2 (AUTHOR) a.l.j.symonds@qmul.ac.uk, Symonds, Alistair² (AUTHOR) p.wang@qmul.ac.uk, Hickman, Oliver J.³ (AUTHOR) oliver.hickman@icr.ac.uk, Wu, Dongsheng⁴ (AUTHOR) dong.wu@qmul.ac.uk, Wang, Ping² (AUTHOR), Lemoine, Nick¹ (AUTHOR) bci-director@qmul.ac.uk, Wang, Yaohe¹ (AUTHOR) yaohe.wang@qmul.ac.uk, Linardopoulos, Spiros³ (AUTHOR) spiros.linardopoulos@icr.ac.uk, Halldén, Gunnel¹ (AUTHOR) g.hallden@qmul.ac.uk

Publikováno v: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 2, p1265. 21p.

Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions.

Autor: Guo, Ju¹ (AUTHOR), Wei, Zhao² (AUTHOR), Jia, Tianwei^3,4,5 (AUTHOR), Wang, Liyang^6,7 (AUTHOR), Nama, Nuosu^6,8 (AUTHOR), Liang, Jiaqian⁹ (AUTHOR), Liao, Xinghua¹⁰ (AUTHOR), Liu, Xiaming¹¹ (AUTHOR), Gao, Yanfei¹² (AUTHOR), Liu, Xiaoqiang¹ (AUTHOR), Wang, Keshan^6,13,14 (AUTHOR) wks4869@hust.edu.cn, Fu, Bin¹ (AUTHOR) urofbin@163.com, Chen, Shaoyong Shawn^1,6 (AUTHOR) shaoyong_chen@hotmail.com

Publikováno v: Journal of Translational Medicine. 10/12/2023, Vol. 21 Issue 1, p1-17. 17p.

Manipulating Myc for reparative regeneration.

Autor: Ascanelli, Camilla, Dahir, Rowda, Wilson, Catherine H.

Publikováno v: Frontiers in Cell & Developmental Biology; 2024, p1-18, 18p