Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Kuo-Hsuan Chang"'
Publikováno v:
Metabolites, Vol 14, Iss 7, p 394 (2024)
Huntington’s disease (HD) is characterized by progressive involuntary chorea movements and cognitive decline. Recent research indicates that metabolic disturbance may play a role in its pathogenesis. Bile acids, produced during cholesterol metaboli
Externí odkaz:
https://doaj.org/article/16359e6ed3724974aad30aac5e6111b3
Autor:
Wen-Yi Huang, Chun-Wei Chang, Kuan-Hsing Chen, Chien-Hung Chang, Hsiu-Chuan Wu, Kuo-Hsuan Chang
Publikováno v:
Renal Failure, Vol 45, Iss 2 (2023)
The incidence of ischemic stroke (IS) is higher in nephrotic syndrome (NS) patients compared to general population. However, there is limited information on the specific characteristics to stroke patients with NS. In this study, we aimed to examine t
Externí odkaz:
https://doaj.org/article/1f9025b78f8d4b9b95514cdf3b9d68e5
Myasthenia gravis and independent risk factors for recurrent infection: a retrospective cohort study
Autor:
Chia-Yin Chien, Chun-Wei Chang, Ming-Feng Liao, Chun-Che Chu, Long-Sun Ro, Yih-Ru Wu, Kuo-Hsuan Chang, Chiung-Mei Chen, Hung-Chou Kuo
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Approximately 10% to 20% of myasthenia gravis (MG) patients have experienced a myasthenic crisis (MC), which contributes to morbidity and mortality. MC triggered by infection is associated with poor outcomes. However, there is a l
Externí odkaz:
https://doaj.org/article/da996c3067b8406d98d162c4d43cdc6d
Autor:
Kuo-Hsuan Chang, Chiung-Mei Chen
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 649 (2024)
Trinucleotide repeat expansion disorders, a diverse group of neurodegenerative diseases, are caused by abnormal expansions within specific genes. These expansions trigger a cascade of cellular damage, including protein aggregation and abnormal RNA bi
Externí odkaz:
https://doaj.org/article/682b23942b874c47830ee83d5450c528
Autor:
Jui-Hung Sun, Yan-Rong Li, Kuo-Hsuan Chang, Miaw-Jene Liou, Shu-Fu Lin, Sung-Sheng Tsai, Ming-Chin Yu, Chuen Hsueh, Szu-Tah Chen
Publikováno v:
Biomedical Journal, Vol 45, Iss 6, Pp 923-930 (2022)
Background: Many patients with papillary thyroid cancer (PTC) demonstrate satisfactory outcomes. However, 8%–28% of patients with PTC show tumor recurrence, which may affect prognosis. Therefore, identifying factors associated with tumor recurrence
Externí odkaz:
https://doaj.org/article/af97d06e7db947179e31968f1f4943fe
Autor:
Kuo-Hsuan Chang, Cheng-Yen Huang, Chih-Hsin Ou-Yang, Chang-Han Ho, Han-Yi Lin, Chia-Lang Hsu, You-Tzung Chen, Yu-Chi Chou, Yi-Jing Chen, Ying Chen, Jia-Li Lin, Ji-Kuan Wang, Pei-Wen Lin, Ying-Ru Lin, Miao-Hsia Lin, Chi-Kang Tseng, Chin-Hsien Lin
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background The c.G6055A (p.G2019S) mutation in leucine-rich repeat kinase 2 (LRRK2) is the most prevalent genetic cause of Parkinson’s disease (PD). CRISPR/Cas9-mediated genome editing by homology-directed repair (HDR) has been applied to
Externí odkaz:
https://doaj.org/article/bc881b164425452fba2c024c95eb8485
Autor:
Wen-Yi Huang, Chun-Wei Chang, Chiung-Mei Chen, Kuan-Hsing Chen, Chien-Hung Chang, Hsiu-Chuan Wu, Kuo-Hsuan Chang
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background The incidence of cerebral stroke, including ischemic infarction and intracranial hemorrhage (ICH), increases in patients with nephrotic syndrome (NS). However, the clinical characteristics of patients with NS and stroke remain elu
Externí odkaz:
https://doaj.org/article/3207f64032ec44e9ac17dd506c05c6c7
Autor:
Bao-Luen Chang, Kuo-Hsuan Chang
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Epilepsy is a common disabling chronic neurological disorder characterized by an enduring propensity for the generation of seizures that result from abnormal hypersynchronous firing of neurons in the brain. Over 20–30% of epilepsy patients fail to
Externí odkaz:
https://doaj.org/article/c7b72dbb3d7a469c856ddf2f96dcf7dd
Autor:
Kuo-Hsuan Chang, Chia-Hsin Liu, Yi-Ru Wang, Yen-Shi Lo, Chun-Wei Chang, Hsiu-Chuan Wu, Chiung-Mei Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7095 (2023)
Increased oxidative stress and neuroinflammation play a crucial role in the pathogenesis of Parkinson’s disease (PD). In this study, the expression levels of 52 genes related to oxidative stress and inflammation were measured in peripheral blood mo
Externí odkaz:
https://doaj.org/article/109d61ad3103448eabf904f278a18f06
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is a rare neuroinflammatory disorder of the central nervous system that typically involves the optic nerve, the spinal cord and other specific brain regions. In relapse of the disease
Externí odkaz:
https://doaj.org/article/acc1ced02d14450f93199108905977b0