Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Kuo Wei Chang"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Metabolic reprogramming sustains malignant head and neck squamous cell carcinoma (HNSCC) to overcome stressful microenvironments, and increased glutamine uptake is a common metabolic hallmark in cancers. Since metabolic reprogramming has bee
Externí odkaz:
https://doaj.org/article/89d38992cae641b083d7c1c7fbc8b070
Publikováno v:
Journal of Dental Sciences, Vol 19, Iss 3, Pp 1380-1388 (2024)
Background/purpose: T cells require second immune checkpoint molecules for activation and immune memory after antigen presentation. We found that inducible co-stimulator (ICOS) has been a favorable prognostic factor amongst B7 immune checkpoint co-st
Externí odkaz:
https://doaj.org/article/ce7a5f1dc5de4ba48ada0b61e0c82f91
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Oral squamous cell carcinoma (OSCC) is a prevalent neoplasm worldwide, necessitating a deeper understanding of its pathogenesis. VGF nerve growth factor inducible (VGF), a neuropeptide, plays critical roles in nerve and endocrine
Externí odkaz:
https://doaj.org/article/50c57b63d0514c7f829ef4022281747d
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Pulp inflammation is complex interactions between different types of cells and cytokines. To mimic the interactions of different types of cells in inflamed dental pulp tissues, dental pulp cells (DPCs) were cocultured with differe
Externí odkaz:
https://doaj.org/article/3be52de34af342fbad730f55e53a5a74
Publikováno v:
Journal of Dental Sciences, Vol 17, Iss 2, Pp 688-695 (2022)
Background/purpose: MicroRNA (miRNA) alterations play important roles in the neoplastic process of oral squamous cell carcinoma (OSCC). Upregulation of miR-10b and miR-372 and downregulation of miR-375 are frequent events in OSCC. The aberrances of t
Externí odkaz:
https://doaj.org/article/d19c7ea4a8004da899858d980056f3f3
Publikováno v:
Journal of Dental Sciences, Vol 17, Iss 2, Pp 659-665 (2022)
Background/purpose: Oral potentially malignant disorder (OPMD) is an important premalignancy worldwide. MicroRNAs (miRNAs) are endogenously expressed non-coding RNAs that regulate the post-transcriptional levels of targeted mRNAs. MiRNA-375 (miR-375)
Externí odkaz:
https://doaj.org/article/1e48488b4b0a47cb94f73630e376dd3e
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Understanding the genomic alterations in oral carcinogenesis remains crucial for the appropriate diagnosis and treatment of oral squamous cell carcinoma (OSCC). To unveil the mutational spectrum, in this study, we conducted whole-exome sequencing (WE
Externí odkaz:
https://doaj.org/article/5dd5a15432a244049d143d6e181d117e
Autor:
Yi-Fen Chen, Chung-Ji Liu, Li-Han Lin, Chung-Hsien Chou, Li-Yin Yeh, Shu-Chun Lin, Kuo-Wei Chang
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background The survival of OSCC patient needs to be further improved. miR-211 is oncogenic in OSCC and its upregulation is associated with tumor progression and poor patient survival. K14-EGFP-miR-211 transgenic mice also exhibit augmented p
Externí odkaz:
https://doaj.org/article/d1d223fdc49043dfa07d228655febc64
Autor:
Wan-Chun Li, Chien-Hsiang Huang, Yi-Ta Hsieh, Tsai-Ying Chen, Li-Hao Cheng, Chang-Yi Chen, Chung-Ji Liu, Hsin-Ming Chen, Chien-Ling Huang, Jeng-Fan Lo, Kuo-Wei Chang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
To support great demand of cell growth, cancer cells preferentially obtain energy and biomacromolecules by glycolysis over mitochondrial oxidative phosphorylation (OxPhos). Among all glycolytic enzymes, hexokinase (HK), a rate-limiting enzyme at the
Externí odkaz:
https://doaj.org/article/a74ef1b417c14e928fb8e49882b2795c
Autor:
Wan-Chun Li, Chien-Hsiang Huang, Yi-Ta Hsieh, Tsai-Ying Chen, Li-Hao Cheng, Chang-Yi Chen, Chung-Ji Liu, Hsin-Ming Chen, Chien-Ling Huang, Jeng-Fan Lo, Kuo-Wei Chang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/e9a440d951c74ce6b1bd43ba95958b71