Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Kuo Ming Wu"'
Autor:
Kenichi Nomoto, Mary Woodall-Jappe, Toshimitsu Uenaka, William H. Gerwick, Yoshihiko Kotake, Hajime Shimizu, Xiaojie Zhu, Hyeong-wook Choi, Steven Mathieu, Kuo-Ming Wu, Yongchun Shen, Karen Tendyke, Sergei Agoulnik, Krista Condon, Donna Kolber-Simonds, Sandeep Akare, Yimin Jiang, Zhihong Chen, Kuan-Chun Huang
Figure S1. Synthesis of [3H]apratoxin A. Figure S2. Synthesis of C.18-epi-apratoxin A. Figure S3. Apratoxin A in vitro IC50 against panels of human cancer cell lines. Table S1. Summary table for in vivo efficacy studies. Figure S4. Apratoxin A concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c65eb6f8b62874049a2fbbb2e9b798
https://doi.org/10.1158/1535-7163.22504099.v1
https://doi.org/10.1158/1535-7163.22504099.v1
Autor:
Kenichi Nomoto, Mary Woodall-Jappe, Toshimitsu Uenaka, William H. Gerwick, Yoshihiko Kotake, Hajime Shimizu, Xiaojie Zhu, Hyeong-wook Choi, Steven Mathieu, Kuo-Ming Wu, Yongchun Shen, Karen Tendyke, Sergei Agoulnik, Krista Condon, Donna Kolber-Simonds, Sandeep Akare, Yimin Jiang, Zhihong Chen, Kuan-Chun Huang
Apratoxin A is a natural product with potent antiproliferative activity against many human cancer cell lines. However, we and other investigators observed that it has a narrow therapeutic window in vivo. Previous mechanistic studies have suggested it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1702da5e1eb71b2ce4a697dd456e12e0
https://doi.org/10.1158/1535-7163.c.6537622.v1
https://doi.org/10.1158/1535-7163.c.6537622.v1
Autor:
Kenichi Nomoto, Mary Woodall-Jappe, Toshimitsu Uenaka, William H. Gerwick, Yoshihiko Kotake, Hajime Shimizu, Xiaojie Zhu, Hyeong-wook Choi, Steven Mathieu, Kuo-Ming Wu, Yongchun Shen, Karen Tendyke, Sergei Agoulnik, Krista Condon, Donna Kolber-Simonds, Sandeep Akare, Yimin Jiang, Zhihong Chen, Kuan-Chun Huang
Figure S1. Synthesis of [3H]apratoxin A. Figure S2. Synthesis of C.18-epi-apratoxin A. Figure S3. Apratoxin A in vitro IC50 against panels of human cancer cell lines. Table S1. Summary table for in vivo efficacy studies. Figure S4. Apratoxin A concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f53f6e76b6cb66b04a95e5af1c1cb98
https://doi.org/10.1158/1535-7163.22504102
https://doi.org/10.1158/1535-7163.22504102
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
The Golgi apparatus is responsible for transporting, processing, and sorting numerous proteins in the cell, including cell surface-expressed receptor tyrosine kinases (RTK). The small-molecule compound M-COPA [2-methylcoprophilinamide (AMF-26)] disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0249e00058cdaced472d1de5d57a772e
https://doi.org/10.1158/0008-5472.c.6507942
https://doi.org/10.1158/0008-5472.c.6507942
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
The antibodies used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b10fca21f6f751eb9923a6e0b53744
https://doi.org/10.1158/0008-5472.22410231.v1
https://doi.org/10.1158/0008-5472.22410231.v1
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
Supplemental Materials and Methods for "Authentication of cell lines"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aaed5bf35b3012d487ac6fac9412bb
https://doi.org/10.1158/0008-5472.22410234.v1
https://doi.org/10.1158/0008-5472.22410234.v1
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
Dose-dependent effects on cell surface expression and processing of MET protein, and phosphorylation status of downstream signaling molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a6f1fdb52085431d22b524097ada9bc
https://doi.org/10.1158/0008-5472.22410249.v1
https://doi.org/10.1158/0008-5472.22410249.v1
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
The effect of M-COPA on cell surface expression of BCRP1 and P-glycoprotein (MDR1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e6d1bfecad16fbffcefa65d31bc4b6
https://doi.org/10.1158/0008-5472.22410240
https://doi.org/10.1158/0008-5472.22410240
Autor:
Shingo Dan, Takao Yamori, Isamu Shiina, Kentaro Yoshimatsu, Hyeong-Wook Choi, Kuo-Ming Wu, Akinobu Akatsuka, Naomi Tamaki, Asaka Hirosawa, Mutsumi Okamura, Yoshimi Ohashi
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404288684a85ef342bc84a5731c7a46a
https://doi.org/10.1158/0008-5472.22410237.v1
https://doi.org/10.1158/0008-5472.22410237.v1