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Akademický článek

Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations

Autor: Kunzhao Du, Zhen Zhang, Zhiwei Zeng, Jinling Tang, Trevor Lee, Tao Sun

Publikováno v: Cell Death and Disease, Vol 12, Iss 7, Pp 1-12 (2021)

Abstract Proper development of the mammalian cerebral cortex relies on precise gene expression regulation, which is controlled by genetic, epigenetic, and epitranscriptomic factors. Here we generate RNA demethylase Fto and methyltransferase Mettl3 co

Externí odkaz: https://doaj.org/article/647add9362d44edfaa25f31ec6c58513

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Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations

Autor: Zhen Zhang, Zhiwei Zeng, Tao Sun, Jinling Tang, Trevor Lee, Kunzhao Du

Publikováno v: Cell Death and Disease, Vol 12, Iss 7, Pp 1-12 (2021)
Cell Death & Disease

Proper development of the mammalian cerebral cortex relies on precise gene expression regulation, which is controlled by genetic, epigenetic, and epitranscriptomic factors. Here we generate RNA demethylase Fto and methyltransferase Mettl3 cortical-sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b5efb10c9fc50917673d52bbd5403b
https://doaj.org/article/647add9362d44edfaa25f31ec6c58513

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Unique and Specific m

Autor: Longbin, Zhang, Kunzhao, Du, Jing, Wang, Yanzhen, Nie, Trevor, Lee, Tao, Sun

Publikováno v: Genes

N6-methyladenosine (m6A)-mediated epitranscriptomic regulation is critical for various physiological processes. Genetic studies demonstrate that proper m6A-methylation is required for mouse brain development and function. Revealing landscapes of m6A-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d6405329b16c31fec6aee16196b38aa3
https://pubmed.ncbi.nlm.nih.gov/32992647

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m6A RNA Methylation Controls Neural Development and Is Involved in Human Diseases

Autor: Kunzhao Du, Tao Sun, Longbin Zhang, Trevor Lee

Publikováno v: Molecular Neurobiology. 56:1596-1606

RNA modifications are involved in many aspects of biological functions. N6-methyladenosine (m6A) is one of the most important forms of RNA methylation and plays a vital role in regulating gene expression, protein translation, cell behaviors, and phys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbfd88869f85ff98531cece9a28c4a44
https://doi.org/10.1007/s12035-018-1138-1

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Unique and Specific m6A RNA Methylation in Mouse Embryonic and Postnatal Cerebral Cortices

Autor: Kunzhao Du, Yanzhen Nie, Longbin Zhang, Tao Sun, Jing Wang, Trevor Lee

Publikováno v: Genes, Vol 11, Iss 1139, p 1139 (2020)
Genes
Volume 11
Issue 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7cda4ea09c6ce9bf6af7932a6b0bda
https://doi.org/10.3390/genes11101139

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Autor: Kunzhao, Du, Longbin, Zhang, Trevor, Lee, Tao, Sun

Publikováno v: Molecular neurobiology. 56(3)

RNA modifications are involved in many aspects of biological functions. N6-methyladenosine (m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78eb90c867d11e70652cea158364b4bf
https://pubmed.ncbi.nlm.nih.gov/29909453

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