Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kunzhang Lin"'
Autor:
Hongyan Zhu, Yan Tao, Siqi Wang, Xutao Zhu, Kunzhang Lin, Ning Zheng, Li Min Chen, Fuqiang Xu, Ruiqi Wu
Publikováno v:
NeuroImage, Vol 289, Iss , Pp 120549- (2024)
The directional organization of multiple nociceptive regions, particularly within obscure operculoinsular areas, underlying multidimensional pain processing remains elusive. This study aims to establish the fundamental organization between somatosens
Externí odkaz:
https://doaj.org/article/a23a41d778e84dac9b25372787fc9359
Autor:
Zengpeng Han, Nengsong Luo, Wenyu Ma, Xiaodong Liu, Yuxiang Cai, Jiaxin Kou, Jie Wang, Lei Li, Siqi Peng, Zihong Xu, Wen Zhang, Yuxiang Qiu, Yang Wu, Chaohui Ye, Kunzhang Lin, Fuqiang Xu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Viral tracers that enable efficient retrograde labeling of projection neurons are powerful vehicles for structural and functional dissections of the neural circuit and for the treatment of brain diseases. Currently, some recombinant adeno-as
Externí odkaz:
https://doaj.org/article/a7f70ce3b4794f4d9c3665ffd5003b65
Autor:
Nengsong Luo, Zengpeng Han, Jiaxin Kou, Yuxiang Cai, Xin Yang, Jie Wang, Kunzhang Lin, Fuqiang Xu
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 16, Iss 06 (2023)
Rabies-viruses-based retrograde tracers can spread across multiple synapses in a retrograde direction in the nervous system of rodents and primates, making them powerful tools for determining the structure and function of the complicated neural circu
Externí odkaz:
https://doaj.org/article/effea69695114172bfec07938caabe5a
Autor:
Zengpeng Han, Nengsong Luo, Jiaxin Kou, Lei Li, Zihong Xu, Siyuan Wei, Yang Wu, Jie Wang, Chaohui Ye, Kunzhang Lin, Fuqiang Xu
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Retrograde tracers based on viral vectors are powerful tools for the imaging and manipulation of upstream neural networks projecting to a specific brain region, and they play important roles in structural and functional studies of neural cir
Externí odkaz:
https://doaj.org/article/aa93c177de994842a52df3c1f004acc1
Autor:
Min Ying, Huadong Wang, Tongtan Liu, Zengpeng Han, Kunzhang Lin, Qing Shi, Ning Zheng, Tao Ye, Huinan Gong, Fuqiang Xu
Publikováno v:
Pathogens, Vol 12, Iss 6, p 814 (2023)
Herpes simplex virus type 1 (HSV-1) is a leading cause of encephalitis and infectious blindness. The commonly used clinical therapeutic drugs are nucleoside analogues such as acyclovir. However, current drugs for HSV cannot eliminate the latent virus
Externí odkaz:
https://doaj.org/article/4d4218bddd8941d1802bd659b6f1072d
Autor:
Zengpeng Han, Nengsong Luo, Fei Wang, Yuxiang Cai, Xin Yang, Weiwei Feng, Zhenxiang Zhu, Jie Wang, Yang Wu, Chaohui Ye, Kunzhang Lin, Fuqiang Xu
Publikováno v:
Viruses, Vol 15, Iss 4, p 848 (2023)
Adeno-associated viruses (AAVs) have become safe and effective tools for therapeutic in vivo gene drug delivery. Among many AAV serotypes, AAV2 is the most well-characterized. Although many studies have been carried out on the engineering of the caps
Externí odkaz:
https://doaj.org/article/93e8be8a0e1840219a4b290d221e8e52
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Recombinant adeno-associated viruses (rAAVs), particularly those that permit efficient gene transfer to neurons from axonal terminals or across the blood–brain barrier, are useful vehicles for structural and functional studies of the neura
Externí odkaz:
https://doaj.org/article/fa9d8f7239934ddb9b2abe3ba5e6b131
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Understanding the connecting structure of brain network is the basis to reveal the principle of the brain function and elucidate the mechanism of brain diseases. Trans-synaptic tracing with neurotropic viruses has become one of the most effe
Externí odkaz:
https://doaj.org/article/1d3ca9e0fe314f199d6302d137af387d
Autor:
Zengpeng Han, Nengsong Luo, Yang Wu, Jiaxin Kou, Wenyu Ma, Xin Yang, Yuxiang Cai, Lin Ma, Lu Han, Xiujie Wang, Hualing Qin, Qing Shi, Jie Wang, Chaohui Ye, Kunzhang Lin, Fuqiang Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12806 (2022)
As powerful tools for local gene delivery, adeno-associated viruses (AAVs) are widely used for neural circuit studies and therapeutical purposes. However, most of them have the characteristics of large diffusion range and retrograde labeling, which m
Externí odkaz:
https://doaj.org/article/e9c53d0e39464d96b0a0f5f8620f8aaa
Autor:
Yang Wu, Liangyu Jiang, Hao Geng, Tian Yang, Zengpeng Han, Xiaobing He, Kunzhang Lin, Fuqiang Xu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 38-47 (2018)
Current large-scale recombinant adeno-associated virus (rAAV) production systems based on the baculovirus expression vector (BEV) remain complicated and cost-intensive, and they lack versatility and flexibility. Here we present a novel recombinant ba
Externí odkaz:
https://doaj.org/article/e509e3daa81b4e2fb2b8aaaa6273d307