Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Kuntang, Shen"'
Publikováno v:
Cancer Medicine, Vol 13, Iss 18, Pp n/a-n/a (2024)
Abstract Background The optimal duration of preoperative imatinib (IM) remains controversial. This study aimed to evaluate the safety, therapeutic effectiveness, and optimal duration of preoperative IM in patients with locally advanced gastric gastro
Externí odkaz:
https://doaj.org/article/5e650198d19843b39d108318598a2852
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-15 (2023)
Abstract Imatinib (IM) has significantly improved the prognosis of gastrointestinal stromal tumor (GIST) patients, but some patients still have primary resistance to IM, and approximately half of patients develop acquired drug resistance within 2 yea
Externí odkaz:
https://doaj.org/article/8696aa6341314dfb85a26cbf138ea723
Autor:
Xiangfei Sun PhD, Qiang Zhang PhD, Ping Shu PhD, Xiaohan Lin PhD, Xiaodong Gao PhD, Kuntang Shen PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Purpose Collectin subfamily member 12, a transmembrane scavenger receptor C-type lectin, is aberrantly expressed in various cancers. However, its physiological role in gastric cancer remains somewhat unclear. This study aimed to investigate the Colle
Externí odkaz:
https://doaj.org/article/cf606987702e4360beba01b1ac7c941d
Autor:
Zhaoqing Tang, Yan Wang, Dan Liu, Xuefei Wang, Chen Xu, Yiyi Yu, Yuehong Cui, Cheng Tang, Qian Li, Jing Sun, Qian Zhang, Yuan Ji, Guifen Ma, Haojie Li, Zhenbin Shen, Kuntang Shen, Rongrong Zheng, Zhiguo Hou, Tianshu Liu, Jiping Wang, Yihong Sun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Surgery is an important part of treatment for gastric adenocarcinoma, however, the consensus on perioperative care is less clear. Here, the authors report the results of a phase II clinical trial investigating neoadjuvant camrelizumab with concurrent
Externí odkaz:
https://doaj.org/article/f6b144877d964639a92b197bb418dedf
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract and are characterized by activating mutations of c-KIT or PDGFRa receptor tyrosine kinases (RTKs). Despite the clinical
Externí odkaz:
https://doaj.org/article/5036c6d29f6445cc969089cd6116b6b8
Autor:
Yan Li, Chen Xu, Bing Wang, Fujiang Xu, Fahan Ma, Yuanyuan Qu, Dongxian Jiang, Kai Li, Jinwen Feng, Sha Tian, Xiaohui Wu, Yunzhi Wang, Yang Liu, Zhaoyu Qin, Yalan Liu, Jing Qin, Qi Song, Xiaolei Zhang, Akesu Sujie, Jie Huang, Tianshu Liu, Kuntang Shen, Jian-Yuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-26 (2022)
The mechanisms of resistance to therapy in gastric cancer remain to be explored. Here, proteomic profiling of 206 tumour tissues from patients treated with chemotherapy and anti-HER2-based therapy results in the identification of four molecular subty
Externí odkaz:
https://doaj.org/article/ace1bc4044db4255a59978634df01a76
Autor:
Zhaoqing Tang, Yan Wang, Yiyi Yu, Yuehong Cui, Liang Liang, Chen Xu, Zhenbin Shen, Kuntang Shen, Xuefei Wang, Tianshu Liu, Yihong Sun
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Adding anti-angiogenics to neoadjuvant chemotherapy for localized gastric cancer is recognized as a promising strategy, but its clinical value remains to be defined. Methods This single-center, single-arm, phase 2 trial included p
Externí odkaz:
https://doaj.org/article/deda8d67ef7f4d468b08c05064acc81b
Autor:
Qi Zhang, Hongshan Wang, Yanhong Xie, Suming Huang, Ke Chen, Botian Ye, Yupeng Yang, Jie Sun, Hongyong He, Fenglin Liu, Zhenbin Shen, Weidong Chen, Kuntang Shen, Yuan Ji, Yihong Sun
Publikováno v:
Endocrine Connections, Vol 10, Iss 8, Pp 947-954 (2021)
A new subcategory, grade 3 neuroendocrine tumors, is incorporated into the grading system of pancreatic neuroendocrine neoplasms in the 2017 WHO c lassification in order to differentiate grade 3 neuroendocrine tumors from neuroendocri ne carcinomas.
Externí odkaz:
https://doaj.org/article/e8ccbeb6de9748b69050c56551846ff6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The effect of immunotherapy strategy has been affirmed in the treatment of various tumors. Nevertheless, the latent role of RNA 5-methylcytosine (m5C) modification in gastric cancer (GC) tumor microenvironment (TME) cell infiltration is still unclear
Externí odkaz:
https://doaj.org/article/359f722a37ef4664b583c3e0f326e3e6
Autor:
Anwei Xue, Xiaodong Gao, Yifeng He, Ping Shu, Xiaowu Huang, Jianyi Sun, Jiangshen Lu, Yingyong Hou, Yong Fang, Kuntang Shen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe clinical benefit of hepatectomy in patients with liver metastases from gastrointestinal stromal tumors (GIST) has not been well defined in this era of tyrosine kinase inhibitor (TKI). Our study aims to demonstrate the survival advantage
Externí odkaz:
https://doaj.org/article/8687f21880fc4a40b9cd994dcd6cc4e0