Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kunqian Yu"'
Autor:
Wenzhi Huang, Shuai Huang, Yanpeng Fang, Tianyu Zhu, Feiyi Chu, Qianhui Liu, Kunqian Yu, Fei Chen, Jie Dong, Wenbin Zeng
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Excited‐state intramolecular proton transfer (ESIPT) has attracted great attention in fluorescent sensors and luminescent materials due to its unique photobiological and photochemical features. However, the current structures are far from
Externí odkaz:
https://doaj.org/article/4727f52872dc4cbd8119743f8ad9fd16
Autor:
Jie Dong, Jie Qian, Kunqian Yu, Shuai Huang, Xiang Cheng, Fei Chen, Hualiang Jiang, Wenbin Zeng
Publikováno v:
Research, Vol 6 (2023)
Monitoring the physiological changes of organelles is essential for understanding the local biological information of cells and for improving the diagnosis and therapy of diseases. Currently, fluorescent probes are considered as the most powerful too
Externí odkaz:
https://doaj.org/article/f03bb5ba113d48b9b2002990cfe894cf
Glycan Epitopes and Potential Glycoside Antagonists of DC-SIGN Involved in COVID-19: In Silico Study
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1586 (2021)
Glycosylation is an important post-translational modification that affects a wide variety of physiological functions. DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) is a protein expressed in antigen-presenti
Externí odkaz:
https://doaj.org/article/c80eeb5284d540d680c15d276853f1b6
Autor:
Quanjiang Ji, Peter J. Chen, Guangrong Qin, Xin Deng, Ziyang Hao, Zdzislaw Wawrzak, Won-Sik Yeo, Jenny Winjing Quang, Hoonsik Cho, Guan-Zheng Luo, Xiaocheng Weng, Qiancheng You, Chi-Hao Luan, Xiaojing Yang, Taeok Bae, Kunqian Yu, Hualiang Jiang, Chuan He
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The WalKR signal transduction system is involved in extracellular signal recognition, but the details of this function are not well established. Here, the authors report the crystal structure of this two-component system alongside the characterisatio
Externí odkaz:
https://doaj.org/article/982278f7c02745b09c2db25ee3867b43
Publikováno v:
Neurosignals, Vol 22, Iss 2, Pp 65-78 (2014)
The small- and intermediate-conductance Ca2+-activated potassium (SK/IK) channels play important roles in the regulation of excitable cells in both the central nervous and cardiovascular systems. Evidence from animal models has implicated SK/IK chann
Externí odkaz:
https://doaj.org/article/270d2ce0ce7d473e84c14f7b1ca4fcb4
Publikováno v:
Molecules, Vol 13, Iss 10, Pp 2426-2441 (2008)
CCR5, as the major co-receptor for HIV-1 entry, is an attractive novel target for the pharmaceutical industry in the HIV-1 therapeutic area. In this study, based on the structures of maraviroc and 1,4-bis(4-(7-chloroquinolin-4-yl)piperazin-1-yl)butan
Externí odkaz:
https://doaj.org/article/9a4aeb148883486eb442bc86f10df21f
Autor:
Quanjiang Ji, Peter J. Chen, Guangrong Qin, Xin Deng, Ziyang Hao, Zdzislaw Wawrzak, Won-sik Yeo, Jenny Winjing Quang, Hoonsik Cho, Guan-Zheng Luo, Xiaocheng Weng, Qiancheng You, Chi-Hao Luan, Xiaojing Yang, Taeok Bae, Kunqian Yu, Hualiang Jiang, Chuan He
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number:11000 (2016); Published 18 March 2016: Updated 6 February 2017 In this Article, we presented a structural and functional characterization of the WalKR two-component system for signal transduction and a small mo
Externí odkaz:
https://doaj.org/article/2233302e69b14a45af7c67bc327b8c11
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101663 (2014)
Ubiquitylation is a universal mechanism for controlling cellular functions. A large family of ubiquitin E3 ligases (E3) mediates Ubiquitin (Ub) modification. To facilitate Ub transfer, RING E3 ligases bind both the substrate and ubiquitin E2 conjugat
Externí odkaz:
https://doaj.org/article/82480d10921c4d0c83968cdebfd5449d
Publikováno v:
Biochemical and Biophysical Research Communications. 618:1-7
Aquaporins (AQPs) transport water molecules across cell membranes. Although most aquaporins are inhibited by mercury ions, AQP6 was reported to be activated by binding mercury ions to residues C155 and C190. Different from C190 and the other pore-lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a561caf0fa2442d5288ca520056d1ba
https://doi.org/10.1016/j.bbrc.2022.06.025
https://doi.org/10.1016/j.bbrc.2022.06.025
Publikováno v:
Ccf Transactions on High Performance Computing
Structure-based virtual screening is a key, routine computational method in computer-aided drug design. Such screening can be used to identify potentially highly active compounds, to speed up the progress of novel drug design. Molecular docking-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9ca37619624357033ff9711d903246
http://europepmc.org/articles/PMC8754542
http://europepmc.org/articles/PMC8754542