Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kunling Yu"'
Autor:
Jian Gao, Jifen Hu, Fang Yu, Chunlin Wang, Danmei Sheng, Wuling Liu, Anling Hu, Kunling Yu, Xiao Xiao, Yi Kuang, Eldad Zacksenhaus, Babu Gajendran, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Lovastatin, an HMG-CoA inhibitor and an effective cholesterol lowering drug, exhibits anti-neoplastic activity towards several types of cancer, although the underlying mechanism is still not fully understood. Herein, we investigat
Externí odkaz:
https://doaj.org/article/951e24cdb29a4642858a3cbf83b27f66
Autor:
Kunling Yu, Sishi Tang, Jishi Wang, Xingyi Kuang, Weili Wang, Bo Hu, Bingqing Cheng, Qing Fang, Dan Ma
Publikováno v:
Experimental Cell Research. 363:196-207
Inhibition of histone deacetylase (HDAC) is a promising therapeutic strategy for various hematologic cancers. Panobinostat has been approved for treating patients with multiple myeloma (MM) by the FDA. Since the mechanism for the resistance of panobi
Autor:
Peifan Li, Danna Wei, Ping Liu, Dan Ma, Jishi Wang, Ping Wang, Qin Fang, Zhen Zhou, Kunling Yu
Publikováno v:
Cellular signalling. 63
B lymphocytes, a key cluster of cells composing the immune system, can protect against abnormal biological factors. Heme oxygenase-1 (HO-1) plays important roles in cell proliferation and immune regulation, but its effects on the development and grow
Autor:
Kunling Yu, Bingqing Cheng, Qin Fang, Sishi Tang, Jishi Wang, Yongling Guo, Tingting Lu, Dan Ma, Weili Wang
Publikováno v:
Life sciences. 207
Purpose HDAC4/5 and Smad7 are potential therapeutic targets for the onset and progression of B-cell acute lymphocytic leukemia (B-ALL) and indices for clinical prognosis. In contrast, HO-1 (heat shock protein 32) plays a key role in protecting tumor
Autor:
Kunling Yu, Yongling Guo, Zhengchang He, Weili Wang, Jishi Wang, Xingyi Kuang, Dan Ma, Jie Xiong, Zhaoyuan Zhang
Publikováno v:
Blood. 132:5128-5128
Purpose Smad ubiquitin regulatory factor 2(Smurf2) as a member of ubiquitinated E3 ligase was certificated to regulate the ubiquitination level of target gene. In this study, smurf2 as tumor suppressor was studied in acute B lymphoblastic leukemia, H
Autor:
Xinyao Li, Kunling Yu, Dan Ma, Tingting Lu, Weili Wang, Xingyi Kuang, Jishi Wang, Zhaoyuan Zhang
Publikováno v:
Blood. 132:5299-5299
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma (NHL). It is a group of adult lymphomas with a large clinical presentation and prognosis heterogeneity. In order to improve the cure rate of diffuse large B-ce