Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Kuniyasu, Soda"'
Autor:
Kuniyasu Soda
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2827 (2023)
The relationship between polyamines and healthy longevity has received much attention in recent years. However, conducting research without understanding the properties of polyamines can lead to unexpected pitfalls. The most fundamental consideration
Externí odkaz:
https://doaj.org/article/b68f0e2eb0ea4b24a7b0039ecd5204d0
Autor:
Hidenori Sanayama, Kiyonori Ito, Susumu Ookawara, Takeshi Uemura, Yoshio Sakiyama, Hitoshi Sugawara, Kaoru Tabei, Kazuei Igarashi, Kuniyasu Soda
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1403 (2023)
Early diagnosis and therapeutic intervention improve the quality of life and prognosis of patients with sarcopenia. The natural polyamines spermine and spermidine are involved in many physiological activities. Therefore, we investigated blood polyami
Externí odkaz:
https://doaj.org/article/27557779a9cf4fee9b8ac5c46bf2cefb
Autor:
Hidenori Sanayama, Kiyonori Ito, Susumu Ookawara, Takeshi Uemura, Sojiro Imai, Satoshi Kiryu, Miho Iguchi, Yoshio Sakiyama, Hitoshi Sugawara, Yoshiyuki Morishita, Kaoru Tabei, Kazuei Igarashi, Kuniyasu Soda
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 746 (2023)
Several mechanisms strictly regulate polyamine concentration, and blood polyamines are excreted in urine. This indicates polyamine accumulation in renal dysfunction, and studies have shown increased blood polyamine concentrations in patients with ren
Externí odkaz:
https://doaj.org/article/c0c7eae35cf54d4abaf287ccd55a4a43
Autor:
Kuniyasu Soda
Publikováno v:
Cells, Vol 11, Iss 1, p 164 (2022)
Polyamines, spermidine and spermine, are synthesized in every living cell and are therefore contained in foods, especially in those that are thought to contribute to health and longevity. They have many physiological activities similar to those of an
Externí odkaz:
https://doaj.org/article/28e93705e88949d8b0d0bd6a0d10e39d
Autor:
Kuniyasu Soda
The human polyamines spermine and spermidine are essential for cell function, and their properties have been extensively studied. However, research results of experiments conducted without understanding the properties of polyamines have been evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4b10b4fe581e0e8dc6f9f3755b357b
https://doi.org/10.20944/preprints202305.1128.v1
https://doi.org/10.20944/preprints202305.1128.v1
Publikováno v:
Medical Sciences, Vol 9, Iss 2, p 22 (2021)
The Japanese diet and the Mediterranean diet are rich in polyamines (spermidine and spermine). Increased polyamine intake elevated blood spermine levels, inhibited aging-associated pro-inflammatory status (increases in lymphocyte function-associated
Externí odkaz:
https://doaj.org/article/4146fa4cf74b457380528b954fe0cdb0
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1254 (2019)
We first demonstrated that long-term increased polyamine (spermine, spermidine, putrescine) intake elevated blood spermine levels in mice and humans, and lifelong consumption of polyamine-rich chow inhibited aging-associated increase in aberrant DNA
Externí odkaz:
https://doaj.org/article/4120bdca3c8244a2af893348e3bb7bfb
Autor:
Kuniyasu Soda
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3106 (2018)
Recent investigations have revealed that changes in DNA methylation status play an important role in aging-associated pathologies and lifespan. The methylation of DNA is regulated by DNA methyltransferases (DNMT1, DNMT3a, and DNMT3b) in the presence
Externí odkaz:
https://doaj.org/article/c3d087229042414e80075c10041bfb3e
Autor:
Kuniyasu Soda
Publikováno v:
Amino Acids. 52:213-224
The polyamines spermidine and spermine are synthesized in almost all organisms and are also contained in food. Polyamine synthesis decreases with aging, but no significant decrease in polyamine concentrations were found in organs, tissues, and blood
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64357 (2013)
Polyamines (spermine and spermidine) play many important roles in cellular function and are supplied from the intestinal lumen. We have shown that continuous high polyamine intake inhibits age-associated pathologies in mice. The mechanism by which po
Externí odkaz:
https://doaj.org/article/95665318f8e045c4b24f7ac754d3c128