Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kunitsugu, Kubota"'
Autor:
Sotaro Ozaka, Akira Sonoda, Shimpei Ariki, Mizuki Minata, Naganori Kamiyama, Shinya Hidano, Nozomi Sachi, Kanako Ito, Yoko Kudo, Astri Dewayani, Thanyakorn Chalalai, Takashi Ozaki, Yasuhiro Soga, Chiaki Fukuda, Kazuhiro Mizukami, Shiori Ishizawa, Mitsue Nishiyama, Naoki Fujitsuka, Sachiko Mogami, Kunitsugu Kubota, Kazunari Murakami, Takashi Kobayashi
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269698 (2022)
Antibiotics disrupt normal gut microbiota and cause dysbiosis, leading to a reduction in intestinal epithelial barrier function. Disruption of the intestinal epithelial barrier, which is known as "leaky gut", results in increased intestinal permeabil
Externí odkaz:
https://doaj.org/article/f369040e15784bfea8b39771f9a9e1cb
Autor:
Kunitsugu Kubota, Toru Kono, Mitsuo Shimada, Atsushi Takata, Jun Higashijima, Kozo Yoshikawa, Takuya Tokunaga, Naoki Fujitsuka, Alessandro Fichera
Publikováno v:
The Journal of Medical Investigation. 70(1-2):180-188
Background : Heineke-Mikulicz (HM) strictureplasty is commonly used to treat short stenoses in Crohn’s disease. However, the degree to which intestinal motility is maintained remains unclear. We compared the peristalsis and transport capacity of th
Autor:
Kunitsugu Kubota, Yumi Harada, Hitomi Sekine, Naoki Fujitsuka, Seiichi Iizuka, Daichi Sadatomi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111860-(2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Autor:
Taro, Oshiro, Yumi, Harada, Kunitsugu, Kubota, Daichi, Sadatomi, Hitomi, Sekine, Mitsue, Nishiyama, Naoki, Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy. 152:113263
Changes in the intestinal microbiota are known to occur in constipated patients. Dietary fiber restriction presents obstacles to appropriate defecation and affects fecal properties, but the relationship between fecal microbiota and fecal morphologica
Autor:
Akinobu Taketomi, Masahiro Yamamoto, Mitsuo Shimada, Kunitsugu Kubota, Yuji Morine, Hiroaki Matsushima, Naoki Fujitsuka, Toru Kono, Akihito Mase
Publikováno v:
Neurogastroenterology and Motility
Background The traditional Japanese herbal medicine, daikenchuto (DKT), has been used to treat constipation and postoperative ileus. However, the precise mechanisms involved in the pharmacological effects of DKT remain uncertain. The aim of this stud
Autor:
Akihito Mase, Kanako Miyano, Kazuaki Tsuchiya, Katsuya Ohbuchi, Toru Kono, A. Kaneko, Masahiro Yamamoto, N. Ohno, Yasuhito Uezono, Kunitsugu Kubota, Hiroaki Matsushima
Publikováno v:
Neurogastroenterology & Motility. 28:1792-1805
Background Stimulation of transient receptor potential ankyrin 1 (TRPA1), which abundantly expressed in enterochromaffin cells (ECC), has been reported to exert apparently contradictory results in in vitro contractility and in vivo gastrointestinal (
Autor:
Yoshio Kase, Suzuro Hitomi, Ryota Imai, Kiichiro Yamaguchi, Kiyotoshi Inenaga, Tomohisa Hattori, Kunitsugu Kubota, Yuji Omiya, Kentaro Ono, Kiyoshi Terawaki
Publikováno v:
Archives of Oral Biology. 66:30-37
Objective Recent studies have demonstrated that mouthwash made with the traditional Japanese medicine hangeshashinto exhibits anti-inflammatory action and alleviates oral mucositis scores, including pain complaints, in patients undergoing chemoradiot
Autor:
Kunitsugu Kubota, Seiichi Iizuka, Yumi Harada, Hitomi Sekine, Daichi Sadatomi, Naoki Fujitsuka
Publikováno v:
Gastroenterology. 158:S-1159
Publikováno v:
Gastroenterology. 158:S-1569
Autor:
Kunitsugu Kubota, Atsushi Kaneko, Mitsue Nishiyama, Taro Oshiro, Naoki Fujitsuka, Hitomi Sekine, Daichi Sadatomi, Yumi Harada
Publikováno v:
Gastroenterology. 158:S-1223