Inhibition of amyloid formation of amyloid β (1–42), amylin and insulin by 1,5-diazacyclooctanes, a spermine-acrolein conjugate

Autor: Kunitomi, Risako, Pradipta, Ambara R., Kawabe, Haruka, Lobsiger, Nadine, Tanaka, Katsunori, Zako, Tamotsu

Publikováno v: In Bioorganic & Medicinal Chemistry 15 September 2021 46

Insulin amyloid polymorphs: implications for iatrogenic cytotoxicity.

Autor: Yuzu K; Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University 2-5, Bunkyo-cho Matsuyama Ehime 790-8577 Japan zako.tamotsu.us@ehime-u.ac.jp., Lindgren M; Department of Physics, Faculty of Natural Sciences, Norwegian University of Science and Technology NO-7491 Trondheim Norway., Nyström S; IFM Chemistry, Linköping University SE-58183 Linköping Sweden., Zhang J; IFM Chemistry, Linköping University SE-58183 Linköping Sweden., Mori W; Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University 2-5, Bunkyo-cho Matsuyama Ehime 790-8577 Japan zako.tamotsu.us@ehime-u.ac.jp., Kunitomi R; Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University 2-5, Bunkyo-cho Matsuyama Ehime 790-8577 Japan zako.tamotsu.us@ehime-u.ac.jp., Nagase T; Department of Metabolism and Endocrinology, Tokyo Medical University Ibaraki Medical Center Ibaraki 300-0395 Japan., Iwaya K; Department of Pathology, Sasaki Institute, Kyoundo Hospital Tokyo 101-0062 Japan., Hammarström P; IFM Chemistry, Linköping University SE-58183 Linköping Sweden., Zako T; Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University 2-5, Bunkyo-cho Matsuyama Ehime 790-8577 Japan zako.tamotsu.us@ehime-u.ac.jp.

Publikováno v: RSC advances [RSC Adv] 2020 Oct 12; Vol. 10 (62), pp. 37721-37727. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).