Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kunitaka Nashiki"'
Autor:
Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceImmunosuppressive Foxp3-expressing regulatory T cells (Tregs) in tumor tissues are assumed to be clonally expanding via recognizing tumor-associated antigens. By single-cell RNA sequencing, we have searched for the molecules that are spec
Autor:
Hidekazu Arai, Yutaka Taketani, Hisae Kume, Kunitaka Nashiki, Tadatoshi Sato, Eiji Takeda, Naoki Sawada, Mitsuyoshi Tsuji, Hironori Yamamoto, Kazusa Muto, Hajime Sasaki, Takeshi Nikawa
Publikováno v:
Toxicology. 227:248-261
Stress, such as trauma and injury, is known to cause transcriptional changes in various tissues; however, there is little information on tissue-specific gene expression in response to stress. Here, we have examined duodenal gene expression in rats su
Autor:
Eiji Takeda, Tadatoshi Sato, Hironori Yamamoto, Hidekazu Arai, Kunitaka Nashiki, Kyoko Morita, Yutaka Taketani, Naoki Sawada, Takeshi Nikawa, Mitsuyoshi Tsuji
Publikováno v:
Journal of Bone and Mineral Metabolism. 24:291-299
Immobilization induces significant and progressive bone loss, with an increase in urinary excretion and a decrease in intestinal absorption of calcium. These actions lead to negative calcium balance and the development of disuse osteoporosis. The aim
Autor:
Masako Ichikawa, Eiji Takeda, Naoki Sawada, Tomoko Takeichi, Kunitaka Nashiki, Yutaka Taketani, Hidekazu Arai, Hironori Yamamoto, Ken-ichi Miyamoto
Publikováno v:
Kidney International. 68(3):1137-1147
Role of membrane microdomains in PTH-mediated down-regulation of NaPi-IIa in opossum kidney cells. Background Parathyroid hormone (PTH) rapidly down-regulates type IIa sodium-dependent phosphate transporter (NaPi-IIa) via an endocytic pathway. Since
Autor:
Kunitaka Nashiki, Yutaka Taketani, Tadatoshi Sato, Hidekazu Arai, Hironori Yamamoto, Eiji Takeda
Publikováno v:
Journal of Cellular and Molecular Medicine. 8:191-200
Inorganic phosphate (Pi) is required for cellular function and skeletal mineralization. Serum Pi level is maintained within a narrow range through a complex interplay between intestinal absorption, exchange with intracellular and bone storage pools,
Autor:
Kiyoshi Ebihara, Daisuke Ohshima, Tohru Izumi, Taro Kishida, Takafumi Mizushige, Miho Watakabe, Manabu Nagamoto, Akio Obata, Yohhei Ohtsu, Kunitaka Nashiki
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 68:508-515
Modulation of the activity and content of cytochrome P-450 (CYP) in hepatic microsomes may be important to human health since these enzymes activate and inactivate a wide range of xenobiotics and food components. Regulation of the inducibility of mos
Publikováno v:
Nutrition and Cancer. 38:209-214
Estradiol is metabolized through two mutually exclusive pathways. 2-Hydroxyestrone (2-OHE,) is antiestrogenic, while 16alpha-hydroxyestrone (16alpha-OHE1) is a potent estrogen. It is suggested that a high urinary 16alpha-OHE1-to-2-OHE1 rato is a biom
Publikováno v:
Journal of Agricultural and Food Chemistry. 48:3872-3875
Mice (4-week-old, male ddy) were fed four isonitrogenic diets for 21 days: purified diet (C diet); fermented soybean (400 mg of soy isoflavonoids/kg; FSB); fermented soybean extract (400 mg of soy isoflavonoid aglycones/kg; FSBE); C with indole-3 car
Autor:
Rieko Tanaka, Emi Shuto, Yutaka Nakaya, Eiji Takeda, Nagakatsu Harada, Minako Sato, Hironori Yamamoto, Kikuko Amo, Kunitaka Nashiki, Masashi Isshiki, Yukihito Higashi, Yutaka Taketani
Publikováno v:
Journal of the American Society of Nephrology : JASN. 20(7)
Excessive dietary phosphorus may increase cardiovascular risk in healthy individuals as well as in patients with chronic kidney disease, but the mechanisms underlying this risk are not completely understood. To determine whether postprandial hyperpho
Autor:
Yutaka Taketani, Hidekazu Arai, Hironori Yamamoto, Hiroko Segawa, Kaori Nomoto, Kunitaka Nashiki, Masashi Isshiki, Naoki Sawada, Eiji Takeda, Masako Ichikawa, Chiharu Ogawa, Tadatoshi Sato, Ken-ichi Miyamoto, Norio Amizuka
Publikováno v:
Bone. 41(1)
Caveolin-1 is an essential and signature protein of caveolae, which are small invaginations of the plasma membrane enriched in cholesterol and sphingolipids. Although high levels of expression of caveolin-1 have been demonstrated in osteoblasts as we