Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kunitaka Hirose"'
Autor:
Kunitaka Hirose, Akira Yamauchi, Itaru Suzuki, Yann Mahe, Christophe Hadjur, Tadahito Takahashi
Publikováno v:
Experimental Dermatology. 22:664-667
To identify potential regulators of normal human melanocyte behaviour, we have developed an in vitro human melanocyte migration assay, using the optically accessible, real-time cell motility assay device TAXIScan. Coating of the glass surface with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae82ea69712f956a489739341d5f21f4
https://doi.org/10.1111/exd.12232
https://doi.org/10.1111/exd.12232
Publikováno v:
Biochemical Journal. 416:55-63
Emerging evidence indicates that Nox (NADPH oxidase) 1-generated ROS (reactive oxygen species) play critical regulatory roles in various cellular processes, yet little is known of direct targets for the oxidase. In the present study we show that one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3fb740828f53d21d339964277b2a9
https://doi.org/10.1042/bj20071259
https://doi.org/10.1042/bj20071259
Autor:
Kunitaka Hirose, John K. Rose, Kazu Okuma, Isao Hamaguchi, Takuya Kohma, Linda Buonocore, Koji Fukagawa, Yukio Hamaguchi, Seiji Tateyama, Masateru Hiyoshi, Youichi Takahama, Keiko Mochida, Toshiaki Mizuochi
Publikováno v:
Japanese journal of infectious diseases. 68(3)
To develop surrogate viruses for hepatitis C virus (HCV), we previously produced recombinant vesicular stomatitis viruses (rVSVs) lacking glycoprotein G but instead expressing chimeric HCV E1/E2 fused to G. These rVSVs were not infectious in HCV-susc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5893182e37dd81b8f3965673e97c237a
https://pubmed.ncbi.nlm.nih.gov/25672345
https://pubmed.ncbi.nlm.nih.gov/25672345
Autor:
Kazunao Kuramoto, Akiyuki Hada, Mikio Yamamoto, Keiichi Higuchi, Masayuki Mori, Jun Sakai, Takuya Chiba, Junjie Yao, Kunitaka Hirose
Publikováno v:
Mammalian Genome. 15:433-451
We applied serial analysis of gene expression (SAGE) to the mouse testis to reveal the global gene expression profile and to identify senescence-dependent changes in that profile. A total of 61,929 SAGE tags, including 19,323 unique tags, were obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a7c394bfbf29de8f0e7312c4940b19
https://doi.org/10.1007/s00335-004-2347-7
https://doi.org/10.1007/s00335-004-2347-7
Autor:
Kunitaka Hirose, Takemasa Takii, Hironori Nakajima, Kikuo Onozaki, Hidetoshi Hayashi, Keiji Miyazawa, Ayako Tamaki, Daichi Katagiri
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:407-410
Rheumatoid arthritis (RA) is characterized by proliferation of synoviocytes that produce proinflammatory cytokines, which is implicated in the pathogenesis of the disease. Among the cytokines, IL-1 is the critical mediator of the disease. When human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebabe247ddea4dffc1888f8d6aee0e5
https://doi.org/10.1248/bpb.27.407
https://doi.org/10.1248/bpb.27.407
Autor:
Naoki Yamamoto, Yoshiaki Niitani, Kunitaka Hirose, Yoshio Koyanagi, Sei Yokoyama-Kumakura, Yuetsu Tanaka, Reiko Tanaka, Kozi Ichiyama, Naoko Miyano-Kurosaki, Mikiro Yanaka, Takeo Edamatsu, Kenji Bannai, Hiroshi Takaku
Publikováno v:
Proceedings of the National Academy of Sciences. 100:4185-4190
A low molecular weight nonpeptide compound, KRH-1636, efficiently blocked replication of various T cell line-tropic (X4) HIV type 1 (HIV-1) in MT-4 cells and peripheral blood mononuclear cells through the inhibition of viral entry and membrane fusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd9cc8ea83445dfa33e0742f5915270
https://doi.org/10.1073/pnas.0630420100
https://doi.org/10.1073/pnas.0630420100
Autor:
Naohide Mori, S. Yoshino, Norio Iizuka, Koutaro Yamamoto, Shouichi Hazama, Kunitaka Hirose, Masaaki Oka, Akira Tangoku, Takafumi Noma
Publikováno v:
British Journal of Cancer
Cytologic examination of peritoneal lavage fluid is a useful predictor of peritoneal recurrence in gastric cancer. However, this technique is not overly sensitive and requires special abilities in the cytologist. In this study, telomerase activity wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74393ce2f5e52601fb9f6e6412764cf
https://doi.org/10.1054/bjoc.2000.1408
https://doi.org/10.1054/bjoc.2000.1408
Autor:
Kazumi Suzukawa, James H. Resau, Ronald G. Crystal, Junji Mitsushita, Koichi Miura, Kunitaka Hirose, Tohru Kamata
Publikováno v:
Journal of Biological Chemistry. 275:13175-13178
Nerve growth factor (NGF) stimulation of pheochromocytoma PC12 cells transiently increased the intracellular concentration of reactive oxygen species (ROS). This increase was blocked by the chemical antioxidant N-acetylcysteine and a flavoprotein inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f30b86e0ae769c0387c33a3b256194
https://doi.org/10.1074/jbc.275.18.13175
https://doi.org/10.1074/jbc.275.18.13175
Autor:
Shigeru Sugino, Shigeru Kimura, Motoharu Kondo, Kiyoshi Asai, Haruki Kato, Shigehiko Mukai, Keiko Akaogi, Yoshiharu Yamamura, Mamoru Inoue, Toshikazu Yoshikawa, Hajime Sano, Kunitaka Hirose
Publikováno v:
Immunopharmacology and Immunotoxicology. 22:221-235
We investigated whether PSK (a polysaccharide from the mycelia of Coriolus versicolor) or OK-432 (a streptococcal preparation) can up-regulate inducible nitric oxide synthase (iNOS) gene expression and nitric oxide (NO) production in mouse peritoneal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d2a04b6c59a2ae643bd2033e84ed37
https://doi.org/10.3109/08923970009016417
https://doi.org/10.3109/08923970009016417
Autor:
Norio Iizuka, Kunitaka Hirose, Tetsuo Fukumoto, Masaaki Oka, Akira Tangoku, Shoichi Hazama, Tosihiro Abe, Nobuko Tokuda
Publikováno v:
Cancer Letters. 142:179-184
Interleukin-1 receptor antagonist (IL-1ra), an endogeneous inhibitor of IL-1, plays an immunosuppressive role in vivo by blocking the proinflammatory effects of IL-1. In the present study, we examined whether IL-1ra expression in human gastric carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0f157336d04b076362b17589ebeb0f
https://doi.org/10.1016/s0304-3835(99)00162-7
https://doi.org/10.1016/s0304-3835(99)00162-7