Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Kunio Yui"'
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 9149-9164 (2023)
The association between the lipid peroxidation product malondialdehyde (MDA)-modified low-density lipoprotein (MDA-LDL) and the pathophysiology of autism spectrum disorder (ASD) is unclear. This association was studied in 17 children with ASD and sev
Externí odkaz:
https://doaj.org/article/5f57033fb718460d8c3905c5c8b98eef
Autor:
George Imataka, Kunio Yui, Yuki Shiko, Yohei Kawasaki, Hitomi Sasaki, Ryoichi Shiroki, Shigemi Yoshihara
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The balance between antioxidant capacity and oxidative stress-induced free radicals may be crucial in the pathophysiological development factor of autism spectrum disorder (ASD). We measured the following urinary and plasma biomarker levels of oxidat
Externí odkaz:
https://doaj.org/article/5133a3e2ed004ea999f2449afc8b8ac6
Autor:
Kunio Yui, George Imataka, Hitomi Sasaki, Yohei Kawasaki, Tohru Okanshi, Ryoichi Shiroki, Shigemi Yoshihara
Publikováno v:
Case Reports in Pediatrics, Vol 2019 (2019)
We investigated the effect of the mammalian target of rapamycin (mTOR) inhibitor everolimus on tuberous sclerosis complex- (TSC-) associated autistic symptoms and focal seizures with impaired awareness in a female child with TSC. We further evaluated
Externí odkaz:
https://doaj.org/article/d92799c0268944029d7531fff11ca386
Contribution of lipid Peroxidation to Social Behaviors in individuals with autism spectrum disorders
Autor:
Kunio Yui, George Imataka, Tomoｙo Hayashi, Mamiko Koshiba, Yuki Shiko, Yohei Kawasaki, Hitomi Sasai
Lipid peroxidation contributes to the development of autism spectrum disorders (ASD). Omega-3 and omega-6 polyunsaturated fatty acids undergo lipid peroxidation, and conversion to malondialdehyde (MDA). The MDA further react with acetaldehyde to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e37c45baf7c844101552de72ba6a855b
https://doi.org/10.21203/rs.3.rs-1718454/v1
https://doi.org/10.21203/rs.3.rs-1718454/v1
Publikováno v:
International Journal of Molecular Sciences. 23:9803
The signaling pathways associated with lipid metabolism contribute to the pathophysiology of autism spectrum disorder (ASD) and provide insights for devising new therapeutic strategies. Prostaglandin E2 is a membrane-derived lipid molecule that contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4fdc17fb7ce7443cfe792e3ce23019
https://doi.org/10.3390/ijms23179803
https://doi.org/10.3390/ijms23179803
Publikováno v:
Cureus
Background Lipid metabolism has been associated with the development of autism. The omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) readily undergo lipid peroxidation and conversion to malondialdehyde (MDA). MDA-modified low-density lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4197148d4936cc5fe50a651d22875f98
https://pubmed.ncbi.nlm.nih.gov/33936898
https://pubmed.ncbi.nlm.nih.gov/33936898
Publikováno v:
Metabolic brain disease. 35(7)
The role of malondialdehyde-modified low-density lipoprotein (MDA-LDL), an oxidized LDL, in the pathophysiology of autism spectrum disorder (ASD) is unclear. We studied association between MDA-LDL and behavioral symptoms in 11 individuals with ASD an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b82c7a42dd81a50a09b0f0190b3fc3
https://pubmed.ncbi.nlm.nih.gov/32643093
https://pubmed.ncbi.nlm.nih.gov/32643093
Publikováno v:
Cureus
Tuberous sclerosis complex (TSC) is a genetic disorder with a high prevalence of associated autism spectrum disorder (ASD). The pathophysiology of TSC mainly involves the hyperactivation of mammalian target of rapamycin (mTOR) induced by TSC1 (hamart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0162ae9e89ef2c36b0186c454ae1935f
https://doi.org/10.7759/cureus.6920
https://doi.org/10.7759/cureus.6920
Publikováno v:
Environmental Science and Pollution Research. 24:9635-9644
Oxidant/antioxidant imbalance may contribute to the pathophysiology of autism spectrum disorder (ASD). We assayed urinary levels of oxidative stress related biomarkers, hexanoyl-lysine (HEL), total antioxidant capacity (TAOC), the DNA methylation bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191be2fc05864194a0f89b15b63af551
https://doi.org/10.1007/s11356-017-8595-3
https://doi.org/10.1007/s11356-017-8595-3
Publikováno v:
Medicinal Chemistry. 12:318-327
Autism spectrum disorders (ASD) may be attributed to altered composition of polyunsaturated fatty acids. We examined the relationships between the plasma ratios of docosahexaenoic acid (DHA)/arachidonic acid (AA) and eicosapentaenoic acid (EPA)/AA, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205b9de60e79c3046ba8a0c9f76481ae
https://doi.org/10.2174/1573406412666160107113725
https://doi.org/10.2174/1573406412666160107113725