Výsledky vyhledávání - "Kunio Takizawa"

Altered growth response of oral mucosal keratinocytes in p53-deficient mice

Autor: Takahiko Toyoshima, Ryutaro Kamijo, Yuko Nakanishi, Daisuke Ito, Kaname Sumitani, Kunio Takizawa, Masao Nagumo

Publikováno v: Journal of Oral Pathology & Medicine. 28:371-376

P53 has important regulatory functions in cell growth, differentiation and apoptosis. Here we analyzed the effects of p53 on the growth response of oral mucosal keratinocytes (OMKCs) using p53-deficient (p53-/-) mice. No morphological difference was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e4cefc08115603b2d0b45f0d38593e
https://doi.org/10.1111/j.1600-0714.1999.tb02056.x

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Enhanced susceptibility to Fas-mediated apoptosis by interferon-.GAMMA. in an oral squamous cell carcinoma cell line

Autor: Masao Nagumo, Toshiaki Takemi, Masayasu Iwase, Kunio Takizawa

Publikováno v: Japanese Journal of Oral & Maxillofacial Surgery. 50:629-635

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41b07721df9dc8693d05805c416c925d
https://doi.org/10.5794/jjoms.50.629

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Inhibitors of cyclooxygenase-2 (COX-2) suppressed the proliferation and differentiation of human leukaemia cell lines

Autor: Yuko Nakanishi, Ryutaro Kamijo, Kunio Takizawa, Masashi Hatori, Masao Nagumo

Publikováno v: European Journal of Cancer. 37:1570-1578

Prostaglandins (PG) are known to play important roles in the proliferation and differentiation of leukaemia cells. The effect of the inhibitors of cyclooxygenase-2 (COX-2), a rate-limiting enzyme for the synthesis of PG, on the proliferation and diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97e3754c108539cc95eac5ff27f4d23
https://doi.org/10.1016/s0959-8049(01)00160-5

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Specific inhibition of cyclooxygenase-2 results in inhibition of proliferation of oral cancer cell lines via suppression of prostaglandin E2 production

Autor: Ryutaro Kamijo, Masashi Hatori, Takahiko Toyoshima, Masao Nagumo, Kunio Takizawa, Kaname Sumitani, Yuko Nakanishi

Publikováno v: Journal of Oral Pathology & Medicine. 30:41-47

Prostaglandins (PGs) are known to play important roles in the proliferation of various types of cancer cells. PGs are produced by the action of cyclooxygenase (COX) enzymes, and two forms of COX, COX-1 and COX-2, have been described. Previous studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c9134d5cc4da97f88934cd879877c3d
https://doi.org/10.1034/j.1600-0714.2001.300107.x

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Synergistic induction of ICAM-1 expression by cisplatin and 5-fluorouracil in a cancer cell line via a NF-κB independent pathway

Autor: Daisuke Ito, Kaname Sumitani, Masao Nagumo, Ryutaro Kamijo, Masashi Hatori, Kunio Takizawa

Publikováno v: British Journal of Cancer

Cisplatin (CDDP) and 5-fluorouracil (5-FU) are common anti-tumour agents, and the anti-tumour effect of CDDP and 5-FU are synergistically enhanced by combined treatment. To clarify the mechanisms of this synergism, we examined the effect of CDDP and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d50b05e916bb12e4abf5ff25f1b3e2c
https://doi.org/10.1038/sj.bjc.6690449

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Nitric Oxide Up-regulates the Expression of Intercellular Adhesion Molecule-1 on Cancer Cells

Autor: Masashi Hatori, Ryutaro Kamijo, Masao Nagumo, Kaname Sumitani, Kunio Takizawa, Takahiko Toyoshima

Publikováno v: Biochemical and Biophysical Research Communications. 257:395-399

Nitric oxide (NO) is an unstable free radical that functions as a cytotoxic agent secreted by macrophages to kill cancer cells. Here we report the effect of NO on the expression of intercellular adhesion molecule-1 (ICAM-1) on cancer cells. NO donors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab8cc0ccc2a539897e1681df136cc3e
https://doi.org/10.1006/bbrc.1999.0476

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Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21

Autor: Takahiko Toyoshima, Daisuke Ito, Ryutaro Kamijo, Masao Nagumo, Kunio Takizawa, Kaname Sumitani

Publikováno v: British Journal of Cancer

Cyclooxygenase-2 is the rate-limiting enzyme in synthesis of prostaglandins and other eicosanoids. Prior reports have shown that inhibition of cyclooxygenase-2 activity, either by selective inhibitors or by antisense oligonucleotide, results in suppr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad4e6ed741976e014abad2c789de6a1
https://pubmed.ncbi.nlm.nih.gov/11953864

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Synergistic induction of the expression of cell adhesion molecules by cisplatin and 5-fluorouracil in a human cancer cell line

Autor: Ryutaro Kamijo, Kunio Takizawa, Masao Nagumo, Daisuke Ito

Publikováno v: International Journal of Oral and Maxillofacial Surgery. 26:110

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eef63e24dd7b862bd3143dbb7b94bb0d
https://doi.org/10.1016/s0901-5027(97)81174-5

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