Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kunio Sannohe"'
Autor:
Tsutomu Katakami, Joji Kamiya, Nobuya Kawauchi, Tadahito Nobori, Tatsuo Kaiho, Haruki Mori, Michihiko Miyamoto, Kunio Sannohe, Tatsuro Yokoyama
Publikováno v:
Journal of Medicinal Chemistry. 35:3325-3330
A series of 6-[(2-aminoethyl)amino]-1,3-dimethyl-2,4(1H,3H)- pyrimidinedione derivatives were synthesized and studied for their class III electrophysiological activity and class II (beta-blocking) effects in in vitro and in vivo models. Structure-act
Publikováno v:
Journal of medicinal chemistry. 40(13)
The effect of 24 newly synthesized quinoline derivatives on tumor cell multidrug resistance (MDR) was examined in vitro. At low concentrations, these compounds enhanced the accumulation of [3H]vincristine in K562/ADM cells and reversed tumor cell MDR
Autor:
Kengo Otsuka, Masahiko Maruyama, Seitaro Kajiya, Toshihiko Ito, Kunio Sannohe, Joji Kamiya, Tatsuo Kaiho, Tsuneji Suzuki
Publikováno v:
Journal of Medicinal Chemistry. 32:351-357
A series of 1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and related compounds were synthesized and evaluated for positive inotropic activity. Most members of this series exerted a dose-dependent increase in myocardial contractilit
Autor:
Joji Kamiya, Kengo Otsuka, Tatsuo Kaiho, Masahiko Maruyama, Toshihiko Ito, Seitaro Kajiya, Tsuneji Suzuki, Kunio Sannohe
Publikováno v:
ChemInform. 20
A series of 1-methyl-7-(4-pyridyl)-5,6,7,8-tetrahydro-3(2H)-isoquinolinones and related compounds were synthesized and evaluated for positive inotropic activity. Most members of this series exerted a dose-dependent increase in myocardial contractilit