Phosphodiesterase Inhibitors Suppress Lactobacillus casei Cell-Wall-Induced NF-κB and MAPK Activations and Cell Proliferation through Protein Kinase A—or Exchange Protein Activated by cAMP-Dependent Signal Pathway

Autor: Takekatsu Saito, Naotoshi Sugimoto, Kunio Ohta, Tohru Shimizu, Kaori Ohtani, Yuko Nakayama, Taichi Nakamura, Yashiaki Hitomi, Hiroyuki Nakamura, Shoichi Koizumi, Akihiro Yachie

Publikováno v: The Scientific World Journal, Vol 2012 (2012)

Specific strains of Lactobacillus have been found to be beneficial in treating some types of diarrhea and vaginosis. However, a high mortality rate results from underlying immunosuppressive conditions in patients with Lactobacillus casei bacteremia.

Externí odkaz: https://doaj.org/article/e6c288f103794b56a96b9a8907fb4570

A significance of school screening electrocardiogram in the patients with ventricular noncompaction

Autor: Keiichi, Hirono, Nariaki, Miyao, Masao, Yoshinaga, Eiki, Nishihara, Kazushi, Yasuda, Shigeru, Tateno, Mamoru, Ayusawa, Naokata, Sumitomo, Hitoshi, Horigome, Mari, Iwamoto, Hideto, Takahashi, Seiichi, Sato, Shigetoyo, Kogaki, Seiko, Ohno, Tadayoshi, Hata, Daisuke, Hazeki, Naomi, Izumida, Masami, Nagashima, Kunio, Ohta, Nobuo, Tauchi, Hiroya, Ushinohama, Shozaburo, Doi, Fukiko, Ichida, Study group on childhood cardiomyopathy in Japan

Publikováno v: Epub 2020 Mar 11

Left ventricular noncompaction (LVNC) is a hereditary cardiomyopathy and is associated with high morbidity and mortality. However, the role and significance of school screening for LVNC have not been fully elucidated. In this multicenter, retrospecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7f436c6ae82da257d6c53a904397a0
https://doi.org/10.1007/s00380-020-01571-7

Severe pulmonary hypertension with fibrodysplasia ossificans progressiva

Autor: Keigo Nishida, Yasuhiro Ikawa, Taichi Nakamura, Kunio Ohta, Taizo Wada

Publikováno v: Pediatrics international : official journal of the Japan Pediatric SocietyReferences. 64(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513d78148a2164d2b7adcbefa28826a2
https://pubmed.ncbi.nlm.nih.gov/35998152

Increased Burden of Ion Channel Gene Variants Is Related to Distinct Phenotypes in Pediatric Patients With Left Ventricular Noncompaction

Autor: Keiichi Hirono, Yukiko Hata, Nariaki Miyao, Mako Okabe, Shinya Takarada, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Hideki Origasa, Naoki Nishida, Fukiko Ichida, Atsuhito Takeda, Atsuya Shimabukuro, Chisato Akita, Daichi Fukumi, Eiki Nishihara, Etsuko Tsuda, Heima Sakaguchi, Hidekazu Ishida, Hideshi Tomita, Hiroaki Kise, Hiroki Nagamine, Hiroki Uchiyama, Hiromi Katayama, Hiroo Ooki, Hiroshi Nishikawa, Hiroshi Ono, Hisanori Sakazaki, Hitoshi Horigome, Jun Muneuchi, Jun Yoshimoto, Junpei Soumura, Masahiro Kamada, Kazushi Yasuda, Kazuyuki Ikeda, Keiji Yasuda, Kenichi Kurosaki, Kenji Mine, Kentaro Ueno, Kiyohiro Takigiku, Kiyoshi Ogawa, Kotaro Inaguma, Kotaro Oyama, Kotaro Urayama, Kunihiko Takahashi, Kunio Ohta, Makoto Nakazawa, Mami Nakayashiro, Mamoro Ayusawa, Manatomo Toyono, Masaki Nii, Masaru Miura, Mitsuhiro Fujino, Naoshi Kuwabara, Nobuo Momoi, Nobuyuki Tsujii, Noriko Motoki, Osamu Matsuo, Reizo Baba, Ryo Inuzuka, Sachiko Kido, Satoru Iwashima, Satoshi Yasukochi, Seigo Okada, Seiichi Sato, Seki Mitsuru, Shigetoyo Kogaki, Shinsuke Hoshino, Shinya Tsukano, Shuhei Fujita, Sumito Kimura, Susumu Urata, Taichi Kato, Takako Toda, Takamichi Uchiyama, Takahiro Shindo, Takashi Higaki, Tomio Kobayashi, Tomoyasu Ozaki, Yasuhiko Tanaka, Yasuhiro Katsube, Yasunobu Hamabuchi, Yo Kajiyama, Yoko Yoshida, Yosuke Murakami, Yuriko Abe, Yoshimi Hiraumi, Yutaka Fukuda, Yutaka Odanaka

Publikováno v: Circulation: Genomic and Precision Medicine. 13

Background: Left ventricular noncompaction (LVNC) is a hereditary type of cardiomyopathy. Although it is associated with high morbidity and mortality, the related ion channel gene variants in children have not been fully investigated. This study aime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5716c030c830177bb9ebca4799b6f714
https://doi.org/10.1161/circgen.119.002940

Tumor necrosis factor-α modifies the effects of Shiga toxin on glial cells

Autor: Naotoshi Sugimoto, Taizo Wada, Akihiro Yachie, Hue Leu, Masaki Shimizu, Kunio Ohta, Tomoko Toma

Publikováno v: International Immunopharmacology. 38:139-143

Shiga toxin (STX) is one of the main factors inducing hemorrhagic colitis and hemolytic-uremic syndrome (HUS) in infections with STX-producing Escherichia coli (STEC). Approximately 62% of patients with HUS showed symptoms of encephalopathy in the 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967275c66de7c7c82ec96e886da99bef
http://hdl.handle.net/2297/45911