Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kunio Matsuhashi"'
Autor:
Mamoru Nomura, Shigeo Harada, Koji Kakihata, Satoshi Takayama, Makoto Shimada, Kunio Matsuhashi, Yukari Sakaguchi
Publikováno v:
The Journal of Toxicological Sciences. 20:309-317
Sprague-Dawley male rats were administered nefiracetam orally at daily doses of 500 and 1500 mg/kg/day for 4 or 9 weeks. Although the copulation index was not affected by nefiracetam treatment, the fertility index was extremely low in the 1500 mg/kg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9296c969d31b4bb5a2686a47be8972cc
https://doi.org/10.2131/jts.20.309
https://doi.org/10.2131/jts.20.309
Publikováno v:
Toxicology and Applied Pharmacology. 105:66-77
In order to determine the neurotoxicity of prenatal and postnatal exposures to neuroactive drugs in developing rats, we examined placental and blood-brain barrier (BBB) transfers of these radiolabeled drugs when they were administered sc to pregnant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db424611d245786cebc6fe28b587ff59
https://doi.org/10.1016/0041-008x(90)90359-3
https://doi.org/10.1016/0041-008x(90)90359-3
Autor:
Kazuhisa Furuhama, Makoto Shimada, Kazuhiro Shimomura, Michiyuki Kato, Katsuko Fujikawa, Kunio Matsuhashi, Miyoko Hagiwara
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 20(4)
The antitumor drug, DE-310, is the slow release form of the camptothecin derivative DX-8951. We investigated a toxicological profile of meningoceles in SD rat fetuses, whose mothers received intravenous DE-310 at several doses, and the time course ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56ccf8ca0403a2354c186c94c53d362
https://pubmed.ncbi.nlm.nih.gov/15869860
https://pubmed.ncbi.nlm.nih.gov/15869860
Publikováno v:
Folia Pharmacologica Japonica. 84:229-241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6953474a06d7dc16f50d3a39fb3839df
https://doi.org/10.1254/fpj.84.229
https://doi.org/10.1254/fpj.84.229
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 85(2)
The drugs used were methamphetamine, reserpine, norepinephrine, epinephrine, propranolol, chlorpromazine, haloperidol, pilocarpine and atropine. Each drug except for reserpine (days 7-13 and 14-19 of gestation) was administered subcutaneously to dams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c198f84a006d8673fc0255d8e75fdbc7
https://pubmed.ncbi.nlm.nih.gov/3988167
https://pubmed.ncbi.nlm.nih.gov/3988167