Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kuninori Yokoyama"'
Publikováno v:
Anesthesia & Analgesia. 108:1631-1637
BACKGROUND: Phenylephrine is a selective alpha(1) adrenergic receptor agonist that increases arterial blood pressure by peripheral vasoconstriction. However, whether phenylephrine improves the outcome of cerebral ischemia in patients with internal ca
Autor:
Yutaka Narumi, Chieko Mitaka, Kuninori Yokoyama, Koshi Makita, Takasuke Imai, Koichi Katsuyama, Yukio Hirata
Publikováno v:
Intensive Care Medicine. 31:718-723
To investigate whether pyrrolidinone derivative (N2733), an inhibitor of nuclear factor (NF)-kappaB activation, improves altered metabolic and hemodynamic changes and organ dysfunctions caused by endotoxic shock.Prospective, randomized, animal study
Autor:
Makoto Sunamori, Takashi Morimoto, Chieko Mitaka, Kuninori Yokoyama, Takasuke Imai, Toshihisa Nosaka
Publikováno v:
Intensive Care Medicine. 28:1103-1109
To test the hypotheses (1) that nitric oxide (NO) production is stimulated after cardiovascular surgery and is related to the hyperdynamic state and (2) that NO production is more prominent in patients with cardiopulmonary bypass.Prospective, clinica
Autor:
Yukio Hirata, Takasuke Imai, Kuninori Yokoyama, Kenichiro Habuka, Yutaka Narumi, Koshi Makita, Chieko Mitaka
Publikováno v:
Critical Care Medicine. 30:1570-1575
The purpose of this study was to examine and compare the effects of atrial natriuretic peptide and furosemide on pulmonary gas exchange, hemodynamics, extravascular lung water, and renal function in a dog model of oleic acid-induced pulmonary edema.P
Publikováno v:
Intensive Care Medicine. 27:243-250
Objective: The purpose of this study was to investigate the effects of aerosolized prostacyclin (A-PGI2) and intratracheally instilled prostacyclin (I-PGI2) during partial liquid ventilation (PLV) on gas exchange and pulmonary circulation in rabbits
Publikováno v:
Intensive Care Medicine. 27:36-41
Objective: To investigate the regional partial pressure of oxygen (PO2) and partial pressure of carbon dioxide (PCO2) of the perfluorocarbon liquid (PpfcO2, PpfcCO2) during partial liquid ventilation (PLV). Design: Prospective, controlled study. Sett
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 47:579-584
Purpose: Previous pharmacokinetic studies of fluorinated anesthetics using19F-magnetic resonance spectroscopy (19F-MRS) have focused on the brain. Investigation of other tissues would give more precise information about the pharmacokinetics of inhala
Publikováno v:
Intensive Care Medicine. 26:117-124
Objective: Excess production of nitric oxide (NO) by inducible NO synthase (iNOS) has been implicated in the pathophysiology of septic shock. This study was designed to see whether S-methylisothiourea sulfate (SMT), a selective inhibitor for iNOS, pr
Publikováno v:
Chest. 113:1658-1666
Study objectives To elucidate the efficacy of the combination of inhaled nitric oxide (NO) and partial liquid ventilation (PLV) in ARDS. Design Prospective, randomized, controlled study. Setting A research laboratory at a university medical center. S
Autor:
Takashi Nagura, K. Ichikawa, Tokujiro Uchida, Chieko Mitaka, Yukio Tsunoda, Yukio Hirata, Kuninori Yokoyama, Keisuke Amaha
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 268:H2017-H2023
To elucidate the role of nitric oxide (NO) in septic shock, we measured hemodynamic and pulmonary gas changes in anesthetized dogs after intravenous administration of bacterial lipopolysaccharide (LPS) with or without NO synthase inhibitor, NG-nitro-