Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kunimichi Niibe"'
Autor:
Maolin Zhang, Kunimichi Niibe, Takeru Kondo, Phoonsuk Limraksasin, Hiroko Okawa, Xinchao Miao, Yuya Kamano, Masahiro Yamada, Xinquan Jiang, Hiroshi Egusa
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Induced pluripotent stem cells (iPSCs) offer an unlimited source for cartilage regeneration as they can generate a wide spectrum of cell types. Here, we established a tetracycline (tet) controlled bone morphogenetic protein-4 ( BMP-4 ) expressing iPS
Externí odkaz:
https://doaj.org/article/1539028e57e3482aa4beebdf326a24a0
Autor:
Xinchao Miao, Kunimichi Niibe, Yunyu Fu, Maolin Zhang, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption. Ameloblast differentiation is regulated by multiple signaling mol
Externí odkaz:
https://doaj.org/article/97c1d00f9dec430e873d852651418853
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Mesenchymal stromal/stem cells (MSCs), which generally expand into adherent monolayers, readily lose their proliferative and multilineage potential following repeated passages. Floating culture systems can be used to generate MSC spheroids, which are
Externí odkaz:
https://doaj.org/article/400bc3273d844f4786352f358bf1b229
Autor:
Maolin Zhang, Xiaochen Zhang, Jiaxin Luo, Ran Yan, Kunimichi Niibe, Hiroshi Egusa, Zhiyuan Zhang, Ming Xie, Xinquan Jiang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Stem cell-based developmental engineering has been considered as a promising strategy for tissue/organ regeneration. Tooth is formed by sequential reciprocal interactions between epithelium derived from surface ectoderm and mesenchymal cells derived
Externí odkaz:
https://doaj.org/article/ccfa4b98cdf7455c850c12af5ed1820d
Autor:
Xinchao Miao, Kunimichi Niibe, Maolin Zhang, Zeni Liu, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7195 (2021)
Amelogenin comprises ~90% of enamel proteins; however, the involvement of Amelx transcriptional activation in regulating ameloblast differentiation from induced pluripotent stem cells (iPSCs) remains unknown. In this study, we generated doxycycline-i
Externí odkaz:
https://doaj.org/article/f178d6b57c6a4612ace186ef05976095
Autor:
Kunimichi Niibe, Maolin Zhang, Kosuke Nakazawa, Satoru Morikawa, Taneaki Nakagawa, Yumi Matsuzaki, Hiroshi Egusa, D.D.S., Ph.D.
Publikováno v:
Japanese Dental Science Review, Vol 53, Iss 2, Pp 25-33 (2017)
Effective regenerative treatments for periodontal tissue defects have recently been demonstrated using mesenchymal stromal/stem cells (MSCs). Furthermore, current bioengineering techniques have enabled de novo fabrication of tooth-perio dental units
Externí odkaz:
https://doaj.org/article/fea73b79b44e4ad68c4343ae4d313212
Autor:
Maolin Zhang, Wenwen Yu, Kunimichi Niibe, Wenjie Zhang, Hiroshi Egusa, Tingting Tang, Xinquan Jiang
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Regenerative medicine for bone tissue mainly depends on efficient recruitment of endogenous or transplanted stem cells to guide bone regeneration. Platelet-derived growth factor (PDGF) is a functional factor that has been widely used in tissue regene
Externí odkaz:
https://doaj.org/article/62d6f4bdeb84483c8b36dfb45ddce74b
Autor:
Yukio Sato, Yo Mabuchi, Kenichi Miyamoto, Daisuke Araki, Kunimichi Niibe, Diarmaid D Houlihan, Satoru Morikawa, Taneaki Nakagawa, Toshihiro Nakajima, Chihiro Akazawa, Shingo Hori, Hideyuki Okano, Yumi Matsuzaki
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165946 (2016)
Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the effects of hypoxia on MSCs remains to be elucidated. This study attempted to uncover the signa
Externí odkaz:
https://doaj.org/article/49c2c11dd8a44f32a6360def86f9c0b7
Autor:
Fangfang Wang, Hiroko Okawa, Yuya Kamano, Kunimichi Niibe, Hiroki Kayashima, Thanaphum Osathanon, Prasit Pavasant, Makio Saeki, Hirofumi Yatani, Hiroshi Egusa
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145677 (2015)
Regenerative dental therapies for bone tissues rely on efficient targeting of endogenous and transplanted mesenchymal stem cells (MSCs) to guide bone formation. Amelogenin is the primary component of Emdogain, which is used to regenerate periodontal
Externí odkaz:
https://doaj.org/article/1802f90db5b643da9976d85aaf096310
Autor:
Kunimichi Niibe, Yoshimi Kawamura, Daisuke Araki, Satoru Morikawa, Kyoko Miura, Sadafumi Suzuki, Shigeto Shimmura, Takehiko Sunabori, Yo Mabuchi, Yasuo Nagai, Taneaki Nakagawa, Hideyuki Okano, Yumi Matsuzaki
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17610 (2011)
Induced pluripotent stem (iPS) cells are generated from mouse and human somatic cells by the forced expression of defined transcription factors. Although most somatic cells are capable of acquiring pluripotency with minimal gene transduction, the poo
Externí odkaz:
https://doaj.org/article/adced516ed7c4775bb5c9deba49d731e