Výsledky vyhledávání - "Kunihiko Nakahara"

Activation of Bone Morphogenetic Protein 4 Signaling Leads to Glomerulosclerosis That Mimics Diabetic Nephropathy

Autor: Takeshi Matsubara, Kunihiko Nakahara, Otoya Ueda, Naoshi Fukushima, Hideharu Abe, Seiji Kishi, Kou-ichi Jishage, Toshio Doi, Tatsuya Tominaga, Toshikazu Araoka, Chisato Goto, Akira Mima, Taichi Murakami, Kojiro Nagai

Publikováno v: Journal of Biological Chemistry. 286:20109-20116

Diabetic nephropathy (DN) is the most common cause of chronic kidney disease. We have previously reported that Smad1 transcriptionally regulates the expression of extracellular matrix (ECM) proteins in DN. However, little is known about the regulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d7b2836c22abed724e65731f325586
https://doi.org/10.1074/jbc.m110.179382

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A monoclonal antibody specific to the granulocyte-derived elastase-fragment D species of human fibrinogen and fibrin: its application to the measurement of granulocyte-derived elastase digests in plasma

Autor: Yumiko Itoh, Kimiko Inuzuka, Kunihiko Nakahara, Yutaka Eguchi, Isao Kohno, Gilbu Soe, Michio Matsuda, Teruko Sugo, Yoichi Sakata, Hideki Murayama

Publikováno v: Blood. 95:1721-1728

When granulocytes are stimulated under certain clinical conditions, elastase is released therefrom and digests fibrin(ogen) independently of the plasmin system, which may also be mobilized simultaneously. Thus, discrimination of these 2 systems becom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2926f0d4c86c6dd2cec908c50ab67d30
https://doi.org/10.1182/blood.v95.5.1721.005k13_1721_1728

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Measurement of soluble fibrin monomer-fibrinogen complex in plasmas derived from patients with various underlying clinical situations

Autor: Kunihiko Nakahara, Kensuke Yamazumi, Shin Koga, Yumiko Kazahaya, Hideo Wada, Michio Matsuda, Yutaka Eguchi, Yuichi Shintani

Publikováno v: Thrombosis and haemostasis. 89(5)

SummaryWe previously reported a monoclonal antibody named IF-43 that specifically recognizes thrombin-modified fibrinogen (desAA- and desAABB- fibrin monomer) bound with fibrinogen or other D1 domain-containing plasmic fragments such as fragments X,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb906ea87c2cb4a1d87ee87a93108a86
https://pubmed.ncbi.nlm.nih.gov/12719780

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Studies on Mesoionic Compounds. II. Mercuration of 3-Phenylsydnone

Autor: Kunihiko Nakahara, Masaki Ohta

Publikováno v: Nippon kagaku zassi. 77:1306-1308

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddb0f67d545bf0fed8ee5f764efcafae
https://doi.org/10.1246/nikkashi1948.77.1306

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Risk factors for chronic kidney disease in Japan: a community-based study

Autor: Jiyoong Kim, Tatsuya Tominaga, Yoko Okumoto, Kunihiko Nakahara, Masafumi Kitakaze, Hideharu Abe, Norimichi Takamatsu, Yumi Ito, Toshio Doi

Publikováno v: BMC Nephrology, Vol 10, Iss 1, p 34 (2009)
BMC Nephrology

Background Chronic kidney disease (CKD) is increasingly being recognized as a predictor for both end-stage renal disease and cardiovascular disease. The present study, conducted on individuals from a community in Arita, Japan, was designed to evaluat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70e9acb07e91290e179937754668d83

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