Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Kunihiko Minakata"'
Autor:
Akiko Murakami, Fumiyuki Takahashi, Fariz Nurwidya, Isao Kobayashi, Kunihiko Minakata, Muneaki Hashimoto, Takeshi Nara, Motoyasu Kato, Ken Tajima, Naoko Shimada, Shin-ichiro Iwakami, Mariko Moriyama, Hiroyuki Moriyama, Fumiaki Koizumi, Kazuhisa Takahashi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86459 (2014)
Accumulating evidence indicates that a small population of cancer stem cells (CSCs) is involved in intrinsic resistance to cancer treatment. The hypoxic microenvironment is an important stem cell niche that promotes the persistence of CSCs in tumors.
Externí odkaz:
https://doaj.org/article/6fe64e8a410a4a28a601b63bfd11afbb
Autor:
Naoko Shimada, Takeshi Nara, Kazuhisa Takahashi, Fariz Nurwidya, Motoyasu Kato, Muneaki Hashimoto, Shigehiro Yagishita, Isao Kobayashi, Akiko Murakami, Kunihiko Minakata, Moulid Hidayat, Fumiyuki Takahashi, Hario Baskoro
Publikováno v:
Biochemical and Biophysical Research Communications. 455:332-338
Insulin-like growth factor 1 receptor (IGF1R) is expressed in many types of solid tumors including non-small cell lung cancer (NSCLC), and enhanced activation of IGF1R is thought to reflect cancer progression. Epithelial-mesenchymal transition (EMT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9f62c7d9394744755d959ed67e0d2d
https://doi.org/10.1016/j.bbrc.2014.11.014
https://doi.org/10.1016/j.bbrc.2014.11.014
Autor:
Kunihiko Minakata, Hiroyuki Moriyama, Muneaki Hashimoto, Kuniaki Seyama, Takeshi Nara, Kazuto Nishio, Fumiyuki Takahashi, Kazuhisa Takahashi, Suzu Yae, Fariz Nurwidya, Fumiaki Koizumi, Akiko Murakami, Ken Tajima
Publikováno v:
Cancer Sci
Somatic mutations in the epidermal growth factor receptor (EGFR) gene, such as exon 19 deletion mutations, are important factors in determining therapeutic responses to gefitinib in non‐small‐cell lung cancer (NSCLC). However, some patients have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7efba6cb8da79a817f68a8aaadf12f
https://doi.org/10.1111/j.1349-7006.2012.02408.x
https://doi.org/10.1111/j.1349-7006.2012.02408.x
Publikováno v:
Oncology Research
A number of large-scale clinical trials have demonstrated that using a combination of oxaliplatin and fluoropyrimidines as an adjuvant chemotherapy for stage II/III colon cancer improved the prognosis. However, there has only been experience in Japan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6548b763a7923d6b51c43203e1e2eb23
https://pubmed.ncbi.nlm.nih.gov/26629945
https://pubmed.ncbi.nlm.nih.gov/26629945
Autor:
Kayo Miura, Masataka Yoshioka, Muneaki Hashimoto, Kazuhisa Takahashi, Shinichi Sasaki, Shin-ichiro Iwakami, Kunihiko Minakata, Fumiyuki Takahashi, Ken Tajima, Toshiji Ishiwata, Takeshi Annoura, Takeshi Nara, Akiko Murakami
Publikováno v:
Respiration. 81:491-498
Background: The lung is one of the sites of granulomatous responses, which are characterized by the recruitment and organization of activated macrophages and lymphocytes. There have been several reports that have shown that some pulmonary granulomato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da8db2d9091a98cdb83801641eb3fb5
https://doi.org/10.1159/000324295
https://doi.org/10.1159/000324295
Autor:
A. Sonia Buist, Lea Schirnhofer, Catherine Beigelman-Aubry, Pierre-Y. Brillet, Tian-tuo Zhang, Andrew J. Fisher, Balazs Dezso, Michael Studnicka, Argyris Tzouvelekis, Christian von Buchwald, Ken Tajima, Charlotte Ringsted, J. Scott Ferguson, Istvan Szatmari, János Podani, Konstantinos Palialexis, Ben-quan Wu, Lei Jiang, Fumiyuki Takahashi, Stavros Anevlavis, Takeshi Annoura, Laszlo Takacs, Demosthenes Bouros, Gaëlle Nachbaur, Thomas Prantzos, Bernhard Kaiser, Marios Froudarakis, Catalin Fetita, Iain Kilty, Masataka Yoshioka, Philippe Grenier, Muneaki Hashimoto, Lars Konge, Druck Reinhardt Druck Basel, Yu-qi Zhou, Bertalan Meskó, Jia-xin Zhu, Jing Huang, Attila Szanto, Hong-tao Li, Min Peng, Marie-H. Becquemin, Xiang Gao, Ronald J. Halbert, Szilárd Póliska, Eszter Csánky, Satz Mengensatzproduktion, Natalie Firlei, André Capderou, Sofia Pozova, Valérie Attali, Kostas Archontogeorgis, Henrik Arendrup, Shin-ichiro Iwakami, Kunihiko Minakata, Kayo Miura, Shinichi Sasaki, Qi Sun, Beáta Scholtz, Augusto A. Litonjua, Elias Primetis, Takeshi Nara, Kui Zhang, Jinming Gao, Akiko Murakami, Gouliamos Athanasios, George Kouliatsis, Geert Verleden, Thomas Similowski, Apostolos Dalakidis, Andreas Koureas, Kazuhisa Takahashi, Fuzhi Lian, Laszlo Nagy, Marc Zelter, Michael J. Allison, Bernd Lamprecht, Toshiji Ishiwata, Ioannis Bougioukas, Lajos Széles, Fei Li
Publikováno v:
Respiration. 81:I-VI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2bf1616df9d14fbc2bfd3c537d7c1c
https://doi.org/10.1159/000327811
https://doi.org/10.1159/000327811
Publikováno v:
Annals of Oncology. 28:ix105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de8588c56e57dc7423766ed2b9dc551
https://doi.org/10.1093/annonc/mdx621.047
https://doi.org/10.1093/annonc/mdx621.047
Autor:
Takeshi Nara, Fariz Nurwidya, Isao Kobayashi, Shin-ichiro Iwakami, Kunihiko Minakata, Naoko Shimada, Muneaki Hashimoto, Ken Tajima, Hiroyuki Moriyama, Akiko Murakami, Mariko Moriyama, Fumiyuki Takahashi, Kazuhisa Takahashi, Motoyasu Kato, Fumiaki Koizumi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e86459 (2014)
PLoS ONE, Vol 9, Iss 1, p e86459 (2014)
Accumulating evidence indicates that a small population of cancer stem cells (CSCs) is involved in intrinsic resistance to cancer treatment. The hypoxic microenvironment is an important stem cell niche that promotes the persistence of CSCs in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f824bd92e0636494feda9107b711356
http://europepmc.org/articles/PMC3904884
http://europepmc.org/articles/PMC3904884
Autor:
Suzu Yae, Hiroyuki Kobayashi, Akiko Murakami, Fariz Nurwidya, Mayumi Tamada, Kunihiko Minakata, Kazuhisa Takahashi, Rika Tsukada, Motoyasu Kato, Kengo Koike, Kuniaki Seyama, Toshifumi Yae, Fumiyuki Takahashi, Momoko Yoshikawa, Takuji Yamaguchi
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)
Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)
Cachexia, a major cause of cancer-related death, is characterized by depletion of muscle and fat tissues, anorexia, asthenia, and hypoglycemia. Recent studies indicate that secretions of proinflammatory cytokines such as interleukin-6 (IL-6) play a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4292598828e822ffe6b355fb638fe28d
https://pubmed.ncbi.nlm.nih.gov/23326296
https://pubmed.ncbi.nlm.nih.gov/23326296
Autor:
Akiko, Murakami, Rina, Ohashi, Kunihiko, Minakata, Ryo, Koyama, Keiko, Muraki, Takehito, Shukuya, Yukiko, Namba, Ryo, Ko, Shigehiro, Yagishita, Yoko, Katsura, Fumiyuki, Takahashi, Shoko, Sakuraba, Kazuhisa, Takahashi
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 39(9)
We retrospectively evaluated the survival benefit of dispensing erlotinib after gefitinib administration in patients with nonsmall cell lung cancer. Ninety patients treated with erlotinib in our hospital were divided into two groups: G+ group patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ced076ddff2ea039876e2734986a3301
https://pubmed.ncbi.nlm.nih.gov/22996769
https://pubmed.ncbi.nlm.nih.gov/22996769