Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kunihiko Hino"'
Autor:
Yusuke Kajiyama, Kentaro Kikuchi, Atsuko Takai, Naomi Hosoya, Hiromi Hoshino, Kunihiko Hino, Hiroshi Miyakawa
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Chronic hepatitis C (CHC) patients frequently suffer from thyroid disorders during interferon therapy. However, the mechanism remains unclear. In this study, we investigated the association between serum B-cell-activating factor belonging to the TNF
Externí odkaz:
https://doaj.org/article/790b1dc867f14dc7b14f5e616dc70494
Autor:
Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Weijia Zang, Yifan Zhang, Tomohiro Akashi, Aaron Viny, Tsukasa Shigehiro, Tomokatsu Ikawa, Hiromi Yamazaki, Miki Fukumoto, Atsushi Tanaka, Yasutaka Hayashi, Yui Koike, Yumi Aoyama, Hiromi Ito, Hiroyoshi Nishikawa, Toshio Kitamura, Akinori Kanai, Akihiko Yokoyama, Tohru Fujiwara, Susumu Goyama, Hideki Noguchi, Stanley C. Lee, Atsushi Toyoda, Kunihiko Hinohara, Omar Abdel-Wahab, Daichi Inoue
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract ATP-dependent chromatin remodeling SWI/SNF complexes exist in three subcomplexes: canonical BAF (cBAF), polybromo BAF (PBAF), and a newly described non-canonical BAF (ncBAF). While cBAF and PBAF regulate fates of multiple cell types, roles f
Externí odkaz:
https://doaj.org/article/693ff5b078c74b6097e1c14e546c55c7
Autor:
Okiru Komine, Syuhei Ohnuma, Kunihiko Hinohara, Yuichiro Hara, Mayuko Shimada, Tomohiro Akashi, Seiji Watanabe, Akira Sobue, Noe Kawade, Tomoo Ogi, Koji Yamanaka
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108872- (2024)
Summary: Recent single-cell analyses have revealed the complexity of microglial heterogeneity in brain development, aging, and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS). Disease-associated microglia (DAMs) have been ident
Externí odkaz:
https://doaj.org/article/d7f739989e174708a15aabfdf39bff50
Autor:
Bojana Jovanović, Daniel Temko, Laura E. Stevens, Marco Seehawer, Anne Fassl, Katherine Murphy, Jayati Anand, Kodie Garza, Anushree Gulvady, Xintao Qiu, Nicholas W. Harper, Veerle W. Daniels, Huang Xiao-Yun, Jennifer Y. Ge, Maša Alečković, Jason Pyrdol, Kunihiko Hinohara, Shawn B. Egri, Malvina Papanastasiou, Raga Vadhi, Alba Font-Tello, Robert Witwicki, Guillermo Peluffo, Anne Trinh, Shaokun Shu, Benedetto Diciaccio, Muhammad B. Ekram, Ashim Subedee, Zachary T. Herbert, Kai W. Wucherpfennig, Anthony G. Letai, Jacob D. Jaffe, Piotr Sicinski, Myles Brown, Deborah Dillon, Henry W. Long, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113564- (2023)
Summary: Triple-negative breast cancer (TNBC) is a heterogeneous disease with limited treatment options. To characterize TNBC heterogeneity, we defined transcriptional, epigenetic, and metabolic subtypes and subtype-driving super-enhancers and transc
Externí odkaz:
https://doaj.org/article/5b7a46fb42fa443eac6a172b0b60048f
Autor:
Takuya Tsujino, Tomoaki Takai, Kunihiko Hinohara, Fu Gui, Takeshi Tsutsumi, Xiao Bai, Chenkui Miao, Chao Feng, Bin Gui, Zsofia Sztupinszki, Antoine Simoneau, Ning Xie, Ladan Fazli, Xuesen Dong, Haruhito Azuma, Atish D. Choudhury, Kent W. Mouw, Zoltan Szallasi, Lee Zou, Adam S. Kibel, Li Jia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Identifying prostate cancer patients who may respond well to PARP inhibitors is important for their success in the clinic. Here, using a genome-wide CRISPR-Cas9 knockout screen, the authors identify MMS22L as a biomarker for sensitivity to PARP inhib
Externí odkaz:
https://doaj.org/article/ae5f553e58e5416b821643fde0923364
Autor:
Sheikh Mohammad Fazle Akbar, Shunji Mishiro, Kazuaki Takahashi, Hiromi Hoshino, Hiroshi Miyakawa, Kunihiko Hino
Publikováno v:
Journal of Medical Virology. 84:1018-1024
Genetic recombination plays a significant role in the survival and evolution of hepatitis C virus (HCV), but methodological limitations have hindered the exploration of genetic recombination. HCV serotypes were evaluated in 104 patients with chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4f1e2ce5ebab5976d12efe670875b3
https://doi.org/10.1002/jmv.23300
https://doi.org/10.1002/jmv.23300
Autor:
Kyoko Hasegawa, Kunihiko Hino, Luvsanbasaryn Narantuya, Hiroaki Okamoto, Yuhko Gotanda, Tsutomu Nishizawa, Masaharu Takahashi, Yasuo Kagawa, Terue Kawabata, Hiromi Hoshino, Ulziiburen Chimedregzen, Fumio Komatsu, Fumio Tsuda, Murdorjyn Altankhuu
Publikováno v:
Clinical and Vaccine Immunology. 11:392-398
The prevalence of infection with hepatitis A virus (HAV), HBV, HCV, HDV, and HEV was evaluated in 249 apparently healthy individuals, including 122 inhabitants in Ulaanbaatar, the capital city of Mongolia, and 127 age- and sex-matched members of noma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cc36f2f8519389da96453a8083fa84
https://doi.org/10.1128/cdli.11.2.392-398.2004
https://doi.org/10.1128/cdli.11.2.392-398.2004
Autor:
Takashi Kumada, Kazuhide Yamamoto, Osamu Yokosuka, Kazuomi Ueshima, Shouta Iwadou, Hiroshi Aikata, Kunihiko Hino, Fumihiko Kanai, Etsuro Hatano, Y. Arai, Kohei Akazawa, Chikara Ogawa, Masatoshi Kudo, Shuntaro Obi, Takuji Okusaka, Hiroaki Nagano, Namiki Izumi, Yutaka Sasaki, Yasuharu Imai
Publikováno v:
Journal of Hepatology. 64:S209-S210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f11922ceac79d8d752b7e8c9bdb7eac
https://doi.org/10.1016/s0168-8278(16)00173-2
https://doi.org/10.1016/s0168-8278(16)00173-2
Autor:
Kazuaki Chayama, Yuzo Miyakawa, Yutaka Komiya, Kenji Ikeda, Masaaki Mizui, Hiromitsu Kumada, Junko Tanaka, Keiko Katayama, Hiroshi Yoshizawa, Junko Kumagai, Kunihiko Hino
Publikováno v:
Journal of Medical Virology. 70:378-386
The Markov model was introduced to simulate natural histories of hepatitis C virus (HCV) infection in men and women. The data set was constructed on 942 HCV carriers who were examined at least once a year without receiving antiviral therapies. Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3624dc90c22a5fcef612409d23d96cc5
https://doi.org/10.1002/jmv.10406
https://doi.org/10.1002/jmv.10406
Autor:
Sachiyo Ohnishi, Kazuaki Takahashi, Hiroshi Maekubo, Jong-Hon Kang, Hiroshi Miyakawa, Yuzo Miyakawa, Shunji Mishiro, Kunihiko Hino
Publikováno v:
Intervirology. 46:308-318
Objective: Ranges of variation and conservation in sequence need to be defined for detecting and genotyping hepatitis E virus (HEV). Methods: Six HEV isolates from Japanese patients were sequenced over the entire genome and compared phylogenetically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b767d0fddfaf862fcc63cb4a9fff6927
https://doi.org/10.1159/000073210
https://doi.org/10.1159/000073210