Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kuniaki Ejima"'
Autor:
Michio Kitajima, Yoshitaka Hishikawa, Takehiko Koji, Kuniaki Ejima, Tadayuki Ishimaru, Akira Fujishita, Yasuaki Shibata, Shirendeb Ulziibat
Publikováno v:
Human Reproduction. 21:2281-2289
BACKGROUND Although intraepithelial lymphocytes (IELs) in human oviductal epithelium have been implicated in the regulation of local immunity, the precise kinetics and mechanism of steroid regulation of IEL are largely unknown. METHODS We examined th
Autor:
Kuniaki Ejima, Mark A. Perrella
Publikováno v:
Antioxidants and Redox Signaling. 6:850-857
Autor:
Mark A. Perrella, Kuniaki Ejima
Publikováno v:
Antioxidants & Redox Signaling. 6:850-857
Sepsis is a systemic inflammatory response to a blood-borne infection that is associated with an extremely high rate of morbidity and mortality. The present article reviews our recent studies involving the role of cyclooxygenase (COX)-2 in host respo
Publikováno v:
Archives of Histology and Cytology. 67:455-464
Keratinocyte growth factor (KGF), a mesenchymal cell derived paracrine growth factor that regulates normal epithelial cell proliferation, appears to be an essential mediator of steroids in various reproductive organs. The present study was designed t
Autor:
Hiroki Nanri, Mark A. Perrella, Irvith M. Carvajal, Matthew D. Layne, Shaw-Fang Yet, Kuniaki Ejima, Bonna Ith
Publikováno v:
Antioxidants & Redox Signaling. 4:569-575
Heme oxygenase (HO) enzymes catalyze the initial reaction in heme catabolism. HO-1 is an inducible isoform that is up-regulated by diverse stimuli, including inflammatory cytokines and factors that promote oxidative stress. HO-1 is a cytoprotective e
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1356:43-52
Exposure to various combinations of cytokines and lipopolysaccharide (LPS) has been reported to increase NO production in vascular endothelial cells. The molecular entity of the newly expressed nitric oxide synthase (NOS) in endothelial cells, howeve
Autor:
Shin-ichi Izumi, Satoshi Inoue, Yasuyoshi Ouchi, Keiko Shukuwa, Kuniaki Ejima, Masami Muramatsu, Takashi Kitaoka, Yoshitaka Hishikawa, Takehiko Koji
Publikováno v:
Histochemistry and cell biology. 126(1)
Diethylstilbestrol (DES) has been implicated in mammalian abnormalities. We examined the effects of DES on follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL) cells in the pituitaries of male mice treated with various do
Autor:
Irvith M. Carvajal, Xiaoli Liu, Rebecca M. Baron, Matthew D. Layne, Alvaro Macias, Yen-Hsu Chen, Laura E. Fredenburgh, Rachel Okabe, Mark A. Perrella, Kuniaki Ejima
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(6)
NO synthase 2 (NOS2) plays an important role in endotoxemia through overproduction of NO. Distamycin A (Dist A) belongs to a class of drugs termed minor-groove DNA binders, which can inhibit transcription factor binding to AT-rich regions of DNA. We
Autor:
Rebecca M. Baron, Matthew D. Layne, Su Wol Chung, Shaw-Fang Yet, Yen-Hsu Chen, Mark A. Perrella, Kuniaki Ejima
Publikováno v:
The Journal of biological chemistry. 278(41)
The inducible isoform of nitric-oxide synthase (NOS2), a key enzyme catalyzing the dramatic increase in nitric oxide by lipopolysaccharide (LPS), plays an important role in the pathophysiology of endotoxemia and sepsis. Recent evidence suggests that
Autor:
Kuniaki Ejima, Patricia A. Kritek, Bruce D. Levy, Irvith M. Carvajal, Jeffrey Vom Saal, Rebecca M. Baron, Matthew D. Layne, Yen-Hsu Chen, Mark A. Perrella, Shaw-Fang Yet
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17(10)
Sepsis is a systemic inflammatory response to a blood-borne infection that is associated with an extremely high rate of morbidity and mortality. The present study investigates the role of cyclooxygenase (COX)-2 in host responses to bacterial endotoxe