Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Kung-Chia Young"'
Autor:
Pin-Nan Cheng, Hung-Yu Sun, I-Che Feng, Yen-Cheng Chiu, Sin-Tian Wang, Dyoness Charmaine Tan, Hung-Chih Chiu, Shih-Chih Chien, Kung-Chia Young
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 1, Pp 20-30 (2023)
Background: Chronic hepatitis C virus (HCV) infection causes various liver diseases and metabolic disorders. With direct-acting antiviral agents (DAAs), which effectively eradicate pan-genotypic HCV, hepatic and concomitant metabolic restorations are
Externí odkaz:
https://doaj.org/article/8e14f2fb40e544038f510a7fa930d288
Autor:
Chao-Ching Chiang, Song-Jeng Huang, Philip Nathaniel Immanuel, Jun-Han Lan, Fang-Yuh Lo, Kung-Chia Young
Publikováno v:
Micromachines, Vol 15, Iss 1, p 21 (2023)
Blood testing is a crucial application in the field of clinical studies for disease diagnosis and screening, biomarker discovery, organ function assessment, and the personalization of medication. Therefore, it is of the utmost importance to collect p
Externí odkaz:
https://doaj.org/article/c5b906e0d0a645f09f741d36a77bceb5
Autor:
Pin-Nan Cheng, Hung-Yu Sun, I-Che Feng, Sin-Tian Wang, Yen-Cheng Chiu, Hung-Chih Chiu, Shih-Chieh Chien, Kung-Chia Young
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 1, Pp 100318- (2023)
Introduction: Hepatitis C (HCV) is associated with extra-hepatic involvment, morbidity as well as metabolic changes. Whether these might be reversible if sustained virologic response (SVR) is achieved by direct-acting antiviral (DAA) therapy remains
Externí odkaz:
https://doaj.org/article/5a2421c7c03140708cd8b04ec9733b71
Autor:
Shuangdi Duan, Jiayi Pi, Chun-Hsiang Wang, Yi-Chou Hou, Chung-Ying Andy Lee, Cheng-Jui Lin, Liyang Shi, Kung-Chia Young, Hung-Yu Sun
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12220- (2022)
Introduction: Indoxyl sulfate (IS), a protein-bound uremic toxin, is associated with kidney function and chronic kidney disease (CKD)-related complications. Currently, serum IS levels are primarily quantified using mass spectrometry-based methods, wh
Externí odkaz:
https://doaj.org/article/177dd40b02c44fbea5dcf586d9944eba
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Sun et al. show that hepatitis C virus or free-fatty acids increase lipid droplets and apolipoprotein J (ApoJ) expression while ApoJ silencing alleviates hepatic lipid accumulation. This study suggests that hepatic ApoJ may activate sterol O-acyltran
Externí odkaz:
https://doaj.org/article/b6481110f1c447b693020f4fbbc72f40
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 5, Pp 715-723 (2020)
Background: The liver maintains blood chemical homeostasis by active uptake and secretion through endocytosis, exocytosis, and intracellular trafficking between the plasma and intracellular membranes. Hepatitis C virus (HCV) infection affects the hos
Externí odkaz:
https://doaj.org/article/5d893808017e40649a29d787385cbd60
Autor:
Ting‐Tsung Chang, Ji‐Hong Cheng, Hung‐Wen Tsai, Kung‐Chia Young, Sun‐Yuan Hsieh, Cheng‐Hsun Ho
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 5, Iss 3, Pp 199-212 (2019)
Abstract Hepatobiliary cancer is the third leading cause of cancer death worldwide. Appropriate markers for early diagnosis, monitoring of disease progression, and prediction of postsurgical outcome are still lacking. As the majority of circulating N
Externí odkaz:
https://doaj.org/article/97d6fbeca62b4d46b2cd6811bdb685ab
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 51, Iss 4, Pp 446-455 (2018)
Background: Hepatitis C virus (HCV) infection has a high persistence rate in patients. Although immune cells play a central role in determining the outcomes of HCV infection, the liver is crucial in controlling HCV activity from acute to chronic stag
Externí odkaz:
https://doaj.org/article/2d97e393780b4687841bddba616cc9af
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006848 (2018)
BACKGROUND:Zika virus (ZIKV) infection causes diseases ranging from acute self-limiting febrile illness to life-threatening Guillain-Barré Syndrome and other neurological disorders in adults. Cumulative evidence suggests an association between ZIKV
Externí odkaz:
https://doaj.org/article/14068a7aa30e4178970fbb21583627e4
Autor:
Yu-Min Lin, Hung-Yu Sun, Wen-Tai Chiu, Hui-Chen Su, Yu-Chieh Chien, Lee-Won Chong, Hung-Chuen Chang, Chyi-Huey Bai, Kung-Chia Young, Chiung-Wen Tsao
Publikováno v:
Viruses, Vol 10, Iss 2, p 57 (2018)
Vitamin D has been identified as an innate anti-hepatitis C virus (HCV) agent but the possible mechanisms for this issue remain unclear. Here, we clarified the mechanisms of calcitriol-mediated inhibition of HCV infection. Calcitriol partially inhibi
Externí odkaz:
https://doaj.org/article/32731d06e42f41559fff306bb566d6cf