Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kung Ban"'
Autor:
Sandra Duffy, Marina Chavchich, Grennady Wirjanata, Silvia Teguh, Susan A. Charman, Rintis Noviyanti, Jitendra R. Harjani, Leonardo Lucantoni, Lian Xue, Jutta Marfurt, Michael D. Edstein, Ric N. Price, Tamir Dingjan, Stuart A. Ralph, Julia G. Beveridge, Michael A. Walters, Katherine M. Ellis, Scott Blundell, Jonathan B. Baell, Darren J. Creek, Fei Huang, Sabine Fletcher, Sarah Diab, Vicky M. Avery, Jayme L. Dahlin, Francis C. K. Chiu, Kung Ban, Jessica M. Strasser, Matthew E. Cuellar, Da Hua Shi
Publikováno v:
Journal of Medicinal Chemistry. 62(5)
A series of 3,3′-disubstituted 5,5′-bi(1,2,4-triazine) derivatives was synthesized and screened against the erythrocytic stage of Plasmodium falciparum 3D7 line. The most potent dimer, 6k, with an IC50 (50% inhibitory concentration) of 0.008 μM,
Autor:
Dorota Maria Ferens, Leni R. Rivera, Brid Callaghan, James A. Brock, Jonathan B. Baell, John B. Furness, Ruslan V Pustovit, Samin Kosari, Trung Van Nguyen, Kung Ban, Daniela M. Sartor
Publikováno v:
British Journal of Pharmacology. 171:1275-1286
Background and Purpose Some agonists of ghrelin receptors cause rapid decreases in BP. The mechanisms by which they cause hypotension and the pharmacology of the receptors are unknown. Experimental Approach The effects of ligands of ghrelin receptors
Autor:
Jonathan B. Baell, Fe C. Abogadie, Brid Callaghan, Haruko Hirayama, Kung Ban, Trung Van Nguyen, Billie Hunne, James A. Brock, Dorota Ferens, John B. Furness, Daniela M. Sartor, Peter McIntyre
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H1011-H1021
Circulating ghrelin reduces blood pressure, but the mechanism for this action is unknown. This study investigated whether ghrelin has direct vasodilator effects mediated through the growth hormone secretagogue receptor 1a (GHSR1a) and whether ghrelin
Autor:
Oliver D. Montagnat, Jonathan B. Baell, Kasiram Katneni, Sandra Duffy, Yelena Khakham, Andrew B. Hughes, Vicky M. Avery, Kung Ban, Eileen Ryan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6024-6029
We report on the discovery of 3-alkylthio-1,2,4-triazine dimers that are potently toxic to Plasmodium falciparum, with single digit nanomolar activity, and up to several thousand-fold lower toxicity to mammalian cells. They are equipotent against chl
Autor:
Brid, Callaghan, Samin, Kosari, Ruslan V, Pustovit, Daniela M, Sartor, Dorota, Ferens, Kung, Ban, Jonathan, Baell, Trung V, Nguyen, Leni R, Rivera, James A, Brock, John B, Furness
Publikováno v:
British journal of pharmacology. 171(5)
Some agonists of ghrelin receptors cause rapid decreases in BP. The mechanisms by which they cause hypotension and the pharmacology of the receptors are unknown.The effects of ligands of ghrelin receptors were investigated in rats in vivo, on isolate
Autor:
Rahmani, Raphaël, Kung Ban, Jones, Amy J., Ferrins, Lori, Ganame, Danny, Sykes, Melissa L., Avery, Vicky M., White, Karen L., Ryan, Eileen, Kaiser, Marcel, Charman, Susan A., Baell, Jonathan B.
Publikováno v:
Journal of Medicinal Chemistry; Sep2015, Vol. 58 Issue 17, p6753-6765, 13p
Autor:
Alshammari, Nawaa Ali H.1,2 (AUTHOR), Bakhotmah, Dina A.1 (AUTHOR)
Publikováno v:
Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 2, p1107-1132. 26p.
Autor:
ALJABRI, Maha1 myjabri@uqu.edu.sa
Publikováno v:
Notulae Botanicae Horti Agrobotanici Cluj-Napoca. 2022, Vol. 50 Issue 3, p1-21. 21p.
Autor:
Shokoohian, Maryam1 (AUTHOR), Hazeri, Nourallah1 (AUTHOR), Maghsoodlou, Malek Taher1 (AUTHOR), Lashkari, Mojtaba2 (AUTHOR)
Publikováno v:
Polycyclic Aromatic Compounds. 2022, Vol. 42 Issue 1, p1-12. 12p.
Publikováno v:
Plants (2223-7747); Feb2019, Vol. 8 Issue 2, p33-1, 1p