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Akademický článek

Distinct Bile Acid Profiles in Patients With Chronic Hepatitis B Virus Infection Reveal Metabolic Interplay Between Host, Virus and Gut Microbiome

Autor: Zeyu Sun, Chenjie Huang, Yixian Shi, Rusha Wang, Jun Fan, Ye Yu, Zhehua Zhang, Kundan Zhu, Minwei Li, Qin Ni, Zhi Chen, Min Zheng, Zhenggang Yang

Publikováno v: Frontiers in Medicine, Vol 8 (2021)

Hepatitis B virus (HBV) can hijack the host bile acids (BAs) metabolic pathway during infection in cell and animal models. Additionally, microbiome was known to play critical role in the enterohepatic cycle of BAs. However, the impact of HBV infectio

Externí odkaz: https://doaj.org/article/6260819a2fd2480ea9cd8a43c03b7e91

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Proton-bound complex mediating retro-Michael-type fragmentation of protonated 3-substituted oxindoles in the Orbitrap high-energy collisional dissociation cell

Autor: Fangliang Tang, Ruonan Cai, Weimin Mo, Qingbao Song, Ye Wang, Xiaoji Cao, Ming Zhang, Kundan Zhu, Yan Lin, Chenlu Wang

Publikováno v: Rapid Communications in Mass Spectrometry. 29:515-520

Rationale Oxindole derivatives are valuable building blocks for indole chemistry. Systematically exploring the fragmentation behavior of the protonated 3-pyrazole-substituted oxindoles by kinetic methods combined with density functional theory (DFT)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::458cad704ccb7dc39d7ef1c974ae6d88
https://doi.org/10.1002/rcm.7128

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Identifying the proton transfer reaction mechanism via a proton-bound dimeric intermediate for esomeprazoles by a kinetic method combined with density functional theory calculations

Autor: Xiaoji Cao, Feifei Zhang, Weimin Mo, Jiaoyu Chen, Xuemin Ye, Lingxiao Shen, Kundan Zhu

Publikováno v: Rapid Communications in Mass Spectrometry. 28:1045-1050

RATIONALE Esomeprazole analogs are a class of important proton pump inhibitors for the treatment of gastro-esophageal reflux diseases. Understanding the fragmentation reaction mechanism of the protonated esomeprazole analogs will facilitate the chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0627debd04e05654350f4c90085d3d27
https://doi.org/10.1002/rcm.6877

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Proton-bound complex mediating retro-Michael-type fragmentation of protonated 3-substituted oxindoles in the Orbitrap high-energy collisional dissociation cell

Autor: Xiaoji, Cao, Kundan, Zhu, Qingbao, Song, Chenlu, Wang, Ye, Wang, Ruonan, Cai, Yan, Lin, Fangliang, Tang, Ming, Zhang, Weimin, Mo

Publikováno v: Rapid communications in mass spectrometry : RCM. 29(6)

Oxindole derivatives are valuable building blocks for indole chemistry. Systematically exploring the fragmentation behavior of the protonated 3-pyrazole-substituted oxindoles by kinetic methods combined with density functional theory (DFT) calculatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15292325ad2246424d713ec7edd429b2
https://pubmed.ncbi.nlm.nih.gov/26160417

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Identifying the proton transfer reaction mechanism via a proton-bound dimeric intermediate for esomeprazoles by a kinetic method combined with density functional theory calculations

Autor: Xiaoji, Cao, Feifei, Zhang, Kundan, Zhu, Xuemin, Ye, Lingxiao, Shen, Jiaoyu, Chen, Weimin, Mo

Publikováno v: Rapid communications in mass spectrometry : RCM. 28(9)

Esomeprazole analogs are a class of important proton pump inhibitors for the treatment of gastro-esophageal reflux diseases. Understanding the fragmentation reaction mechanism of the protonated esomeprazole analogs will facilitate the characterizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efc369c3e425e64603a66a8bdefe9cd3
https://pubmed.ncbi.nlm.nih.gov/24677526

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