Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Kunal Dhiman"'
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Akademický článek
Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective Longitudinal Study
Autor: Kunal Dhiman, Victor L. Villemagne, Christopher Fowler, Pierrick Bourgeat, Qiao-Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins, Veer Gupta
Publikováno v: Biomedicines, Vol 10, Iss 5, p 1045 (2022)
Background: Biomarkers that are indicative of early biochemical aberrations are needed to predict the risk of dementia onset and progression in Alzheimer’s disease (AD). We assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL)
Externí odkaz: https://doaj.org/article/f02d7207870d46cd8d5801b8507b29f1
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2
Akademický článek
Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease
Autor: Kunal Dhiman, Veer Bala Gupta, Victor L. Villemagne, Dhamidhu Eratne, Petra L. Graham, Christopher Fowler, Pierrick Bourgeat, Qiao‐Xin Li, Steven Collins, Ashley I. Bush, Christopher C. Rowe, Colin L. Masters, David Ames, Eugene Hone, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins
Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cog
Externí odkaz: https://doaj.org/article/365c6fec1fde4184b2c9e8e883ae53b3
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5
Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell-cell interactions in the pathophysiology of neurological disease
Autor: Angela Godinez, Rashi Rajput, Nitin Chitranshi, Veer Gupta, Devaraj Basavarajappa, Samridhi Sharma, Yuyi You, Kanishka Pushpitha, Kunal Dhiman, Mehdi Mirzaei, Stuart Graham, Vivek Gupta
Publikováno v: Cellular and molecular life sciences : CMLS. 79(3)
Neuroserpin is an axonally secreted serpin that is involved in regulating plasminogen and its enzyme activators, such as tissue plasminogen activator (tPA). The protein has been increasingly shown to play key roles in neuronal development, plasticity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9ab7bc67c63a68942483b2551a440b
https://pubmed.ncbi.nlm.nih.gov/35244780
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6
Comparative Analysis of Aducanumab, Zagotenemab and Pioglitazone as Targeted Treatment Strategies for Alzheimer's Disease
Autor: Mehdi Mirzaei, Stuart L. Graham, Paul A. Haynes, Ghasem H. Salekdeh, Kunal Dhiman, Ting Shen, Samran Sheriff, Anna Meyfour, Ardeshir Amirkhani, Yunqi Wu, Nitin Chitranshi, Veer Gupta, Vivek Gupta, Morteza Abyadeh
Publikováno v: Aging and Disease
Alzheimer’s disease (AD) is the leading cause of dementia that has remained a major medical, sociocultural and economical challenge globally. Previously developed treatments like anticholinesterase inhibitors (AChEIs) and N-methyl-D-aspartate recep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3d891cb6b91b58c3a20b6d2373383b
https://pubmed.ncbi.nlm.nih.gov/34881080
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7
Cerebrospinal fluid levels of fatty acid-binding protein 3 are associated with likelihood of amyloidopathy in cognitively healthy individuals
Autor: Kunal Dhiman, Victor L. Villemagne, Christopher Fowler, Pierrick Bourgeat, Qiao‐Xin Li, Steven Collins, Christopher C. Rowe, Colin L. Masters, David Ames, Kaj Blennow, Henrik Zetterberg, Ralph N. Martins, Veer Gupta
Publikováno v: Alzheimer'sdementia (Amsterdam, Netherlands). 14(1)
Fatty acid-binding protein 3 (FABP3) is a biomarker of neuronal membrane disruption, associated with lipid dyshomeostasis-a notable Alzheimer's disease (AD) pathophysiological change. We assessed the association of cerebrospinal fluid (CSF) FABP3 lev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e85cbf76c288a36c027e8207942c505
https://pubmed.ncbi.nlm.nih.gov/36479019
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