Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kun-jian Gu"'
Autor:
Kristin Bowman-James, Krzysztof Kuczera, Garegin Papoyan, Joanna Wiorkiewicz-Kuczera, Kun-jian Gu
Publikováno v:
Journal of the American Chemical Society. 118:1354-1364
Nitrate complexes of two different polyammonium macrocycles, the tetrahydrogen nitrate salts of 1,4,7,16,19,21-hexaaza-10,13-dioxacyclotetracosane [24]N6O2·4HNO3, 1, and 1,4,10,13-tetraaza-7,16-dioxacyclooctadecane, [18]N4O2·4HNO3, 2, have been iso
Autor:
Kun-jian Gu, Kristin Bowman-James
Publikováno v:
Tetrahedron Letters. 36:1977-1980
A facile route is described for the synthesis of polyazaoxamacrocycles with pendant chains that is applicable for the preparation of a variety of macrocycles of differing ring size and heteroatom substitution.
Autor:
Billie Key, Michael Victor Voronkov, Michael J. Crist, N. Andrew Whitlock, Beth McKnight, Suma Gopinathan, Gardyan Michael Walter, Kun Jian Gu, Bryce Alden Harrison, Zheng Y. Almstead, Craig E. Crosson, Ross Mabon, Dennis S. Rice, Phil W. Yates, Alan G. E. Wilson, Jason Allen, Nita Patel, Ying Liu, Brian D. Hamman, David B. Rawlins, Qingyun Liu, Yulian Zhang, Lawrence F. Courtney, Julia Zhou, S. David Kimball
Publikováno v:
Journal of medicinal chemistry. 52(21)
The discovery of a pyrrolopyrimidine class of LIM-kinase 2 (LIMK2) inhibitors is reported. These LIMK2 inhibitors show good potency in enzymatic and cellular assays and good selectivity against ROCK. After topical dosing to the eye in a steroid induc
Autor:
Bryce A. Harrison, N. Andrew Whitlock, Michael V. Voronkov, Zheng Y. Almstead, Kun-jian Gu, Ross Mabon, Michael Gardyan, Brian D. Hamman, Jason Allen, Suma Gopinathan, Beth McKnight, Mike Crist, Yulian Zhang, Ying Liu, Lawrence F. Courtney, Billie Key, Julia Zhou, Nita Patel, Phil W. Yates, Qingyun Liu
Publikováno v:
Journal of Medicinal Chemistry; Nov2009, Vol. 52 Issue 21, p6515-6518, 4p
Publikováno v:
The Journal of Organic Chemistry. 52:1662-1666
Publikováno v:
Tetrahedron Letters. 30:1323-1326
A convergent route is described for the preparation of unsymmetrical N-substituted polyammonium macrocycles that is potentially applicable for the synthesis of a wide variety of macrocycles of differing ring size and heteroatom substitution.
Publikováno v:
ChemInform. 18