Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kun-he Zhang"'
Autor:
Shao-Song Liu, Qin-Si Wan, Cong Lv, Jin-Ke Wang, Song Jiang, Dan Cai, Mao-Sheng Liu, Ting Wang, Kun-He Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Gastric cancer (GC) lacks serum biomarkers with clinical diagnostic value. Multi-omics analysis is an important approach to discovering cancer biomarkers. This study aimed to identify and validate serum biomarkers for GC diagnosis
Externí odkaz:
https://doaj.org/article/8da255b7e9054ba092b82099cdc86bd9
Publikováno v:
BioMedical Engineering OnLine, Vol 22, Iss 1, Pp 1-30 (2023)
Abstract Modern omics technologies can generate massive amounts of biomedical data, providing unprecedented opportunities for individualized precision medicine. However, traditional statistical methods cannot effectively process and utilize such big
Externí odkaz:
https://doaj.org/article/e5d7af2d94804f21bcfd8401bc68aae7
Autor:
Hong-Li Zhang, Cong Lv, Zi-Hua Li, Song Jiang, Dan Cai, Shao-Song Liu, Ting Wang, Kun-He Zhang
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Introduction: Aptamers are valuable for bioassays, but aptamer-target binding is susceptible to reaction conditions. In this study, we combined thermofluorimetric analysis (TFA) and molecular dynamics (MD) simulations to optimize aptamer-target bindi
Externí odkaz:
https://doaj.org/article/1ba5203fbcf4437db98ca62f0c176bee
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Background and AimsAptamers are artificial ligands that bind to biological targets with high specificity and affinity. We previously selected a group of aptamers against the serum of primary hepatic carcinoma (PHC) via systematic evolution of ligands
Externí odkaz:
https://doaj.org/article/558aa77036454f58bcde885641103114
Autor:
Xu Zhou, Dong-mei Yan, Wei-feng Zhu, Wen-jun Liu, He-yun Nie, Sheng Xu, Yi-ping Jiang, Kun-he Zhang, Ying Fu, Yi-ye Wan, Xin-yu Yu, Hong Li, Xin Sun, Xiao-fan Chen
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Spleen qi deficiency (SQD), a syndrome based on traditional Chinese medicine (TCM) theory, is common in patients after radical gastrectomy. SQD manifests with chronic gastrointestinal disorders and systemic symptoms and is challen
Externí odkaz:
https://doaj.org/article/ab685b4c70d04a85a10586740c7f5ee7
Autor:
Jia Hu, Ting Wang, Kun-He Zhang, Yi-Ping Jiang, Song Xu, Si-Hai Chen, Yu-Ting He, Hai-Liang Yuan, Yu-Qi Wang
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Extrahepatic metastasis is the independent risk factor of poor survival of primary hepatic carcinoma (PHC), and most occurs in the chest and abdomen. Currently, there is still no available method to predict thoracoabdominal extrah
Externí odkaz:
https://doaj.org/article/d9bf130d3359458c98a210e8a0aa2863
Autor:
Ting Wang, Kun-He Zhang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
An early diagnosis of hepatocellular carcinoma (HCC) followed by effective treatment is currently critical for improving the prognosis and reducing the associated economic burden. Alpha-fetoprotein (AFP) is the most widely used biomarker for HCC diag
Externí odkaz:
https://doaj.org/article/d040e2bd8a1f43dda7885b250cd6093e
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Background: Hepatocellular carcinoma (HCC) frequently occurs in cirrhosis and closely relates to poor prognosis of cirrhotic patients. Alpha-fetoprotein (AFP) is the most widely used biomarker in HCC diagnosis but not sensitive and specific to detect
Externí odkaz:
https://doaj.org/article/33d1874280614355ba03edaaad18dcfb
Autor:
Si-Hai Chen, Qin-Si Wan, Di Zhou, Ting Wang, Jia Hu, Yu-Ting He, Hai-Liang Yuan, Yu-Qi Wang, Kun-He Zhang
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Objective: This study aimed to develop and validate a simple-to-use nomogram for early hepatocellular carcinoma (HCC) patients undergoing a preoperative consultation and doctors conducting a postoperative evaluation.Methods: A total of 2,225 HCC pati
Externí odkaz:
https://doaj.org/article/18d6897fa1c6466890ab993ee4931c5a
Publikováno v:
Tumor Biology, Vol 39 (2017)
Gastrointestinal cancer is a leading contributor to cancer-related morbidity and mortality worldwide. Early diagnosis currently plays a key role in the prognosis of patients with gastrointestinal cancer. Despite the advances in endoscopy over the las
Externí odkaz:
https://doaj.org/article/88f3bb7628824c58a6610909de50faef