Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kun-Zhi Zhang"'
Autor:
Kai-long Jiang, Chang-mei Liu, Li-tong Nie, Hai-ni Jiang, Lei Xu, Kun-zhi Zhang, Li-xia Fan, An-hui Gao, Lu-ling Lin, Xiang-yu Wang, Ming-jia Tan, Qi-qing Zhang, Yu-bo Zhou, Jia Li
Publikováno v:
Acta pharmacologica Sinica. 44(1)
Inositol-requiring enzyme 1α (IRE1α) is the most conserved endoplasmic reticulum (ER) stress sensor with two catalytic domains, kinase and RNase, in its cytosolic portion. IRE1α inhibitors have been used to improve existing clinical treatments aga
Autor:
Kailong Jiang, Jia Li, Hejing Huang, Huanan Liu, Chang-Mei Liu, Xianchao Cao, Fajun Nan, Li-xia Fan, Jian Hou, Kun-Zhi Zhang, Hu Xiaobei, Xinwen Zhang, Anhui Gao, Yubo Zhou
Publikováno v:
Cancer letters. 360(2)
Identifying chemotherapy candidates with high selectivity against cancer cells is a major challenge in cancer treatment. Tumor microenvironments cause chronic endoplasmic reticulum (ER) stress and activate the unfolded protein response (UPR) as an ad
Autor:
Jia Li, Kun-Zhi Zhang, Haowen Jiang, Li-xia Fan, Jing-Ya Li, Yubo Zhou, Yan-Yun Fu, Fajun Nan, Anhui Gao, Mei Zhang, Chong-Gang Yuan
Publikováno v:
Biochimica et biophysica acta. 1840(7)
Background Several anti-diabetes drugs exert beneficial effects against metabolic syndrome by inhibiting mitochondrial function. Although much progress has been made toward understanding the role of mitochondrial function inhibitors in treating metab