Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Kun-Hua Yu"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 151, Iss , Pp 113177- (2022)
Amyloidoses are caused by the deposition of amyloid fibrils ascribed to protein misfolding. In this study, we examined the antiamyloidogenic and antioxidative activities of quercetin, a plant flavonol from the flavonoid group of polyphenols, on mouse
Externí odkaz:
https://doaj.org/article/2495d7bd92064810933010b3ee656ea0
Quercetin Disaggregates Prion Fibrils and Decreases Fibril-Induced Cytotoxicity and Oxidative Stress
Autor:
Kun-Hua Yu, Cheng-I Lee
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1081 (2020)
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases caused by misfolding and aggregation of prion protein (PrP). Previous studies have demonstrated that quercetin can disaggregate some amyloid fibrils, such as amyloi
Externí odkaz:
https://doaj.org/article/3a1df989d593484686818270f3c6c4a9
Publikováno v:
Pathogens, Vol 2, Iss 3, Pp 506-519 (2013)
Misfolding and aggregation into amyloids of the prion protein (PrP) is responsible for the development of fatal transmissible neurodegenerative diseases. Various studies on curcumin demonstrate promise for the prevention of Alzheimer’s disease and
Externí odkaz:
https://doaj.org/article/902476b8dae34bc8959a1ca6e7a975e3
Autor:
Kun-Hua Yu, 游昆樺
102
Transmissible spongiform encephalopathies (TSE) is a fatal neurodegenerative disease caused by misfolding and aggregation of prion protein (PrP). Recent studies have demonstrated that the quercetin has protective effect against Aβ (1–42)
Transmissible spongiform encephalopathies (TSE) is a fatal neurodegenerative disease caused by misfolding and aggregation of prion protein (PrP). Recent studies have demonstrated that the quercetin has protective effect against Aβ (1–42)
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/2ap96p
Publikováno v:
International Journal of Nanomedicine
Wen-Hsuan Tsai,1 Kun-Hua Yu,1 Yi-Cheng Huang,2 Cheng-I Lee1 1Department of Biomedical Sciences, National Chung Cheng University, Min-Hsiung, Chia-Yi, Taiwan, Republic of China; 2Department of Food Science, National Taiwan Ocean University, Keelung Ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09207350256c0f21ee014b5e54a20967
http://europepmc.org/articles/PMC5810525
http://europepmc.org/articles/PMC5810525
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1800, p 1800 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Misfolding of prion protein (PrP) into amyloid aggregates is the central feature of prion diseases. PrP has an amyloidogenic C-terminal domain with three α-helices and a flexible tail in the N-terminal domain in which multiple octapeptide repeats ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0927b89abc078fee294487fa1dd9dfaf
https://doi.org/10.3390/ijms22041800
https://doi.org/10.3390/ijms22041800
Publikováno v:
Pharmaceutics
Antibiotic resistance has become a crisis. Candida tropicalis (C. tropicalis) is one of the most highly virulent and drug-resistant pathogens. An alternative antimicrobial therapy to eradicate C. tropicalis effectively, without the risk of developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35ac177737099cf71e7e7a2166a1bb07
https://pubmed.ncbi.nlm.nih.gov/30621174
https://pubmed.ncbi.nlm.nih.gov/30621174
Autor:
Cheng-I Lee, Jun-Hui Zhang, Xian-Bin Huang, Kun-Hua Yu, Yao-Chang Lee, Yi-Hsuan Hsieh, Wen-Ching Chuang
Publikováno v:
International Journal of Molecular Sciences; Volume 19; Issue 2; Pages: 337
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 2, p 337 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 2, p 337 (2018)
Candida albicans is the most commonly encountered human fungal pathogen, and it is traditionally treated with antimicrobial chemical agents. The antimicrobial effect of these agents is largely weakened by drug resistance and biofilm-associated virule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7915a10c6a64e66fecfe2299274258cb
Publikováno v:
Pharmaceutics
Volume 11
Issue 1
Volume 11
Issue 1
Antibiotic resistance has become a crisis. Candida tropicalis (C. tropicalis) is one of the most highly virulent and drug-resistant pathogens. An alternative antimicrobial therapy to eradicate C. tropicalis effectively, without the risk of developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6b7b613531e2dd089795abc2bd5256
https://doi.org/10.3390/pharmaceutics11010016
https://doi.org/10.3390/pharmaceutics11010016
Autor:
Shen-Jie Lin1 gonkasim@gmail.com, Kun-Hua Yu1 ykhuna@gmail.com, Jhih-Ru Wu2 chengpingkevincheng@gmail.com, Chin-Fa Lee2 biohrc@ccu.edu.tw, Cheng-Ping Jheng1 sana18077@gmail.com, Hau-Ren Chen1 cfalee@dragon.nchu.edu.tw, Cheng-I Lee1 biocil@ccu.edu.tw
Publikováno v:
International Journal of Molecular Sciences. Sep2013, Vol. 14 Issue 9, p17943-17957. 15p. 2 Diagrams, 5 Graphs.