Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kun-Han Chuang"'
Autor:
Meng Xu, Ling Lin, Babul Moni Ram, Omprakash Shriwas, Kun-Han Chuang, Siyuan Dai, Kuo-Hui Su, Zijian Tang, Chengkai Dai
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112557- (2023)
Summary: Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is tuned quantitatively remains poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat shock response, a
Externí odkaz:
https://doaj.org/article/de966cf3984742a3847cf8fefb928fe6
Autor:
Shu Yang, Xuefeng Wu, Euphrosyne I Daoutidou, Ya Zhang, MaryJane Shimell, Kun-Han Chuang, Aidan J Peterson, Michael B O'Connor, Xiaoyan Zheng
Publikováno v:
eLife, Vol 11 (2022)
Hedgehog (Hh) and Bone Morphogenetic Proteins (BMPs) pattern the developing Drosophila wing by functioning as short- and long-range morphogens, respectively. Here, we show that a previously unknown Hh-dependent mechanism fine-tunes the activity of BM
Externí odkaz:
https://doaj.org/article/5383f019d9724b6689d2cd6c1cae0d03
Publikováno v:
Journal of hypertension. 40(10)
Vascular calcification has been considered as a potential therapeutic target in pulmonary hypertension. Mg2+ has a protective role against calcification. This study aimed to investigate whether Mg2+ could alleviate pulmonary hypertension by reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d9b7d5f4795f334fddad3721efeaad
https://pubmed.ncbi.nlm.nih.gov/36052522
https://pubmed.ncbi.nlm.nih.gov/36052522
Autor:
Meng Xu, Ling Lin, Kun-Han Chuang, Babul Ram, Siyuan Dai, Kuo-Hui Su, Zijian Tang, Chengkai Dai
Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is attuned quantitatively remain poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat-shock, or proteotoxic str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52a7783c823dd0f37db0a2abc647242
https://doi.org/10.1101/2022.02.22.481519
https://doi.org/10.1101/2022.02.22.481519
Autor:
Xuefeng Wu, Shu Yang, Euphrosyne I Daoutidou, Ya Zhang, MaryJane Shimell, Kun-Han Chuang, Aidan J Peterson, Michael B O'Connor, Xiaoyan Zheng
Publikováno v:
eLife, Vol 11 (2022)
Hedgehog (Hh) and Bone Morphogenetic Proteins (BMPs) pattern the developing Drosophila wing by functioning as short- and long-range morphogens, respectively. Here, we show that a previously unknown Hh-dependent mechanism fine-tunes the activity of BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36da8bc102b184a5f5a512379b5a14c4
https://doi.org/10.7554/elife.73357
https://doi.org/10.7554/elife.73357
Autor:
Xuefeng Wu, Shu Yang, Euphrosyne I Daoutidou, Ya Zhang, MaryJane Shimell, Kun-Han Chuang, Aidan J Peterson, Michael B O'Connor, Xiaoyan Zheng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d460b5901fd00748bef113250e8d01f4
https://doi.org/10.7554/elife.73357.sa2
https://doi.org/10.7554/elife.73357.sa2
Autor:
Shu, Yang, Xuefeng, Wu, Euphrosyne I, Daoutidou, Ya, Zhang, MaryJane, Shimell, Kun-Han, Chuang, Aidan J, Peterson, Michael B, O'Connor, Xiaoyan, Zheng
Publikováno v:
eLife. 11
Hedgehog (Hh) and Bone Morphogenetic Proteins (BMPs) pattern the developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5648f382d54a2b06d27d4d525ed8e98c
https://pubmed.ncbi.nlm.nih.gov/35037619
https://pubmed.ncbi.nlm.nih.gov/35037619
Magnesium Supplementation Attenuates Pulmonary Hypertension via Regulation of Magnesium Transporters
Autor:
Long Xin Gui, Wei Jie Zhu, Ru Hui Yao, Dan Wang, Mo Jun Lin, Da Cen Lin, Kun Han Chuang, Zhuang Li Zhu, James S.K. Sham, Si Yi Zheng
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 77(2)
Pulmonary hypertension (PH) is characterized by profound vascular remodeling and altered Ca 2+ homeostasis in pulmonary arterial smooth muscle cells (PASMCs). Magnesium ion (Mg 2+ ), a natural Ca 2+ antagonist and a cofactor for numerous enzymes, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ad7a562bf6967b4a3c36131c41a8b2
https://pubmed.ncbi.nlm.nih.gov/33356397
https://pubmed.ncbi.nlm.nih.gov/33356397
Autor:
Weiqun Peng, Yan Kai, Yunxiao Meng, Chia Han Lee, Zhuo Liu, Nancy R. Gough, Wenge Zhu, Yixuan Li, Javid Ghaemmaghami, Fengdong Cheng, Alexandros Tzatsos, Kun Han Chuang, Xiaoyan Zheng, Eduardo M. Sotomayor, Meghana Keswani, Xuefeng Wu, Yongbao Zhuang, Xiaojun Wu, Edward Seto, Ya Zhang
Publikováno v:
JCI Insight. 4
Clinical and preclinical studies show tissue-specific differences in tumorigenesis. Tissue specificity is controlled by differential gene expression. We prioritized genes that encode secreted proteins according to their preferential expression in nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e5d7324fae9ac747432be14b9b9941
https://doi.org/10.1172/jci.insight.129344
https://doi.org/10.1172/jci.insight.129344
Autor:
Dan Wang, Zhuang-Li Zhu, Da-Cen Lin, Si-Yi Zheng, Kun-Han Chuang, Long-Xin Gui, Ru-Hui Yao, Wei-Jie Zhu, Sham, James S. K., Mo-Jun Lin, Wang, Dan, Zhu, Zhuang-Li, Lin, Da-Cen, Zheng, Si-Yi, Chuang, Kun-Han, Gui, Long-Xin, Yao, Ru-Hui, Zhu, Wei-Jie, Lin, Mo-Jun
Publikováno v:
Hypertension (0194911X); Feb2021, Vol. 77 Issue 2, p617-631, 15p