Zobrazeno 1 - 10
of 1 488
pro vyhledávání: '"Kun Xia"'
Autor:
Shiyu Zhang, Zheng Wang, Yijing Wang, Yixiao Zhu, Qiao Zhou, Xingxing Jian, Guihu Zhao, Jian Qiu, Kun Xia, Beisha Tang, Julian Mutz, Jinchen Li, Bin Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The metabolomic profile of aging is complex. Here, we analyse 325 nuclear magnetic resonance (NMR) biomarkers from 250,341 UK Biobank participants, identifying 54 representative aging-related biomarkers associated with all-cause mortality. W
Externí odkaz:
https://doaj.org/article/c603a664612e43f99fdb8d1fec1514d6
Autor:
Zhuohui Chen, Xiang Wang, Ziwei Teng, Jing Huang, Jianzhong Mo, Chunrun Qu, Yinghua Wu, Zhixiong Liu, Fangkun Liu, Kun Xia
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105314- (2024)
Summary: Background: Medications prescribed for chronic diseases can lead to short-term neuropsychiatric symptoms, but their long-term effects on brain structures and psychiatric conditions remain unclear. Methods: We comprehensively analyzed the FDA
Externí odkaz:
https://doaj.org/article/a2725491b2504404a7b05feb71061a99
Autor:
Jiyong Li, Rongze Ma, Xuebing Wang, Yunzhe Lu, Jing Chen, Deyi Feng, Jiecan Zhou, Kun Xia, Ophir Klein, Hao Xie, Pengfei Lu
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-15 (2024)
Abstract Stromal fibroblasts are a major stem cell niche component essential for organ formation and cancer development. Fibroblast heterogeneity, as revealed by recent advances in single-cell techniques, has raised important questions about the orig
Externí odkaz:
https://doaj.org/article/aff9ba566f4a4e87a1959c4687857166
Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation
Autor:
Yi-Yi Wang, Guo-Qiang Zhu, Kun Xia, Hong-Bo Zeng, Yun-Hui He, Hui Xie, Zhen-Xing Wang, Ran Xu
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Benign prostatic hyperplasia (BPH) is a prevalent disease affecting elderly men, with chronic inflammation being a critical factor in its development. Omentin-1, also known as intelectin-1 (ITLN-1), is an anti-inflammatory protein
Externí odkaz:
https://doaj.org/article/ed30143537cd4836a149a5a8a953b01e
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background Exportin 1 (XPO1) is a nuclear export protein that facilitates the transportation of various substances. XPO1 promotes tumor development as a poor prognostic factor in a variety of tumors and is a therapeutic target for screening
Externí odkaz:
https://doaj.org/article/9e85b79500204e42a22fe63b033988d3
Autor:
Zichao Zhang, Jing Chen, Rongze Ma, Chongshen Xu, Yunzhe Lu, Jiecan Zhou, Kun Xia, Pengfei Lu
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract The genetic basis of vertebrate emergence during metazoan evolution has remained largely unknown. Understanding vertebrate‐specific genes, such as the tight junction protein Occludin (Ocln), may help answer this question. Here, it is shown
Externí odkaz:
https://doaj.org/article/d7838e7cdc9b47e5b3544abcb1fdebdb
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract Tumor heterogeneity, the presence of multiple distinct subpopulations of cancer cells between patients or among the same tumors, poses a major challenge to current targeted therapies. The way these different subpopulations interact among the
Externí odkaz:
https://doaj.org/article/763a55fa21174592b9986d3519216918
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Primary familial brain calcification (PFBC), also known as Fahr’s disease, is a central nervous system calcium deposition disorder with symmetrical basal ganglia calcification. Most PFBC cases are caused by SLC20A2 gene variant. We report a Chinese
Externí odkaz:
https://doaj.org/article/aef6d8136d10421998838dab4261612f
Publikováno v:
IEEE Access, Vol 12, Pp 93848-93858 (2024)
This article proposes a method for diagnosing arc faults in the brush slip ring system of a Doubly-Fed Induction Generator (DFIG) using image recognition technology. The aim is to achieve automatic detection and diagnosis of arc faults. The experimen
Externí odkaz:
https://doaj.org/article/1ada8e910fb34363b24fb2d014feb344
Autor:
Yuanfeng Huang, Qian Chen, Zheng Wang, Yijing Wang, Aojie Lian, Qiao Zhou, Guihu Zhao, Kun Xia, Beisha Tang, Bin Li, Jinchen Li
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Substantial evidence shown that the age at onset (AAO) of Parkinson’s disease (PD) is a major determinant of clinical heterogeneity. However, the mechanisms underlying heterogeneity in the AAO remain unclear. To investigate the risk factor
Externí odkaz:
https://doaj.org/article/2ab4e991460f4a9ea0541ae83a60696e