Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kun I. Lin"'
Autor:
Ying-Tzu Chang, Yu-Ning Teng, Kun-I Lin, Charles C. N. Wang, Susan L. Morris-Natschke, Kuo-Hsiung Lee, Chin-Chuan Hung
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR
Externí odkaz:
https://doaj.org/article/aadb4fb6502e4754853b555fcbdbf894
Autor:
Ping-Ping Wu, An-Cheng Huang, Kun-I Lin, Tai-An Chiang, Shu-Fen Peng, Po-Yuan Chen, Ching-Lung Liao, Jaw-Chyun Chen, Fu-Shin Chueh, Jin-Cherng Lien
Publikováno v:
Anticancer Research. 41:4343-4351
Background/aim Ally lisothiocyanate (AITC), a constituent of naturally occurring isothiocyanates (ITCs) found in some Brassica vegetables, has been previously demonstrated to have anti-carcinogenic activity. However, there is no available information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1902f87b2aa717391e35fbf3c5ce755
https://doi.org/10.21873/anticanres.15239
https://doi.org/10.21873/anticanres.15239
Autor:
Chung-Shan Yu, Ho-Lein Huang, Kuo-Yen Liao, Kun-I Lin, Kee-Ching Jeng, Yi-Hsian Lin, Kai-Shiang Chang, Wen-Chin Su, Yin-Cheng Huang, Li-Wu Chiang
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 3058-3081 (2012)
1-Aminophytosphingosine and 6-aminogalactosyl phytosphingosine were prepared in 61% and 40% yield libraries with 44 carboxylic acids showed that a 4-butylbenzoic acid-derived product exe, respectively. Glycosylation using benzoyl-protected lipid resu
Externí odkaz:
https://doaj.org/article/3ecf8dd80c6f4a968e83dd5c62dbe85f
Publikováno v:
Molecules, Vol 15, Iss 12, Pp 8796-8803 (2010)
The previous discoveries of butyl fenbufen amide analogs with antitumor effects were further examined. The amide analogs with 1, 3, 4 and 8 carbons chains were prepared in 70-80% yield. Fenbufen had no cytotoxic effects at concentrations ranging from
Externí odkaz:
https://doaj.org/article/81126daf9e6749288bf49a915940380e
Autor:
Chia Jen Lee, Ching Wen Hu, Kok Tong Tan, Ching Shiang Chi, Fu Mei Huang, Kun I. Lin, Chia Herng Yue, Jer-Yuh Liu, Ying Ru Pan
Publikováno v:
Anticancer Research. 39:4149-4164
Background/aim Signaling regulation of myeloid zinc finger 1 (MZF1) has been implicated in the progression of many human malignancies; however, the mechanistic action of MZF1 in triple-negative breast cancer (TNBC) progression remains elusive. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdb206751ead5152e3f0a9200b88729
https://doi.org/10.21873/anticanres.13574
https://doi.org/10.21873/anticanres.13574
Autor:
Jian Wu Lai, Ching Lun Su, Hwa Chien, Jenn Shyong Chen, Yen Hsyang Chu, Kun I. Lin, Meng Yuan Chen, Chien Ya Wang
Publikováno v:
Journal of Atmospheric and Oceanic Technology. 36:297-315
A VHF pulsed radar system was set up on the Taoyuan County seashore (24°57′58″N, 121°00′30″E; Taiwan) to observe the sea surface in the northern Taiwan Strait for the first time. The radar used a four-element, vertically polarized Yagi ante
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6ec73f64f9a26d3355387e4f11545d6
https://doi.org/10.1175/jtech-d-18-0110.1
https://doi.org/10.1175/jtech-d-18-0110.1
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 85
Background P-glycoprotein (P-gp) over-expression plays a vital role in not only systemic drug bioavailability but also cancer multi-drug resistance (MDR). Develop functional inhibitors of P-gp can conquer both problems. Purpose and study design The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6e90b479bf84ee549b753ccd223bf3
https://pubmed.ncbi.nlm.nih.gov/33735724
https://pubmed.ncbi.nlm.nih.gov/33735724
Publikováno v:
Cancers
Cancers, Vol 11, Iss 11, p 1746 (2019)
Volume 11
Issue 11
Cancers, Vol 11, Iss 11, p 1746 (2019)
Volume 11
Issue 11
Both gemcitabine and fluoropyrimidine are recommended backbones in the first-line treatment of pancreatic ductal adenocarcinoma (PDAC). To compare the efficacy and safety of these two therapeutic backbones, and to investigate the optimal therapies, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f87306b72be2be0a3b2208b546ad62
https://pubmed.ncbi.nlm.nih.gov/31703359
https://pubmed.ncbi.nlm.nih.gov/31703359
Autor:
Chin-Chuan Hung, Yu-Ning Teng, Susan L. Morris-Natschke, Kuo Hsiung Lee, Kun-I Lin, Charles C.N. Wang, Ying-Tzu Chang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Multidrug resistance presents an obstacle in cancer treatment. Among numerous combative strategies, collateral sensitivity (CS) drugs have opened a new avenue to defeat cancer by exploiting selective toxicity against multidrug-resistant (MDR) cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a8ae87d33ac1a70cca3c00760e4773
https://doi.org/10.1038/s41598-019-48169-2
https://doi.org/10.1038/s41598-019-48169-2
Autor:
Chang-Han Chen, Jui-Chi Lai, Shyh Ming Kuo, Mei-Ling Hsu, Huey-Ling You, You-Qi Wang, Li Yen Shiu, Kun-I Lin, Chih-Chien Lin
Publikováno v:
Bioscience Reports
Carnosic acid (CA), a major polyphenolic diterpene present in Rosmarinus officinalis, has been reported to have multiple functions, including antitumor activity. The MTT assay, BrdU incorporation, wound healing, and colony formation were used to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ca330018f08b534ae303e8bd29a4ba
http://europepmc.org/articles/PMC6028752
http://europepmc.org/articles/PMC6028752