Structural insights into Arabidopsis ethylene response factor 96 with an extended N-terminal binding to GCC box

Autor: Kun-Hung Chen, Pei-Hsuan Lin, Yi-Sheng Cheng, Chun-Yen Chen

Publikováno v: Plant Molecular Biology

The phytohormone ethylene is widely involved in many developmental processes and is a crucial regulator of defense responses against biotic and abiotic stresses in plants. Ethylene-responsive element binding protein, a member of the APETALA2/ethylene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53ad6f23d6d824aeed26b075dea356c
https://pubmed.ncbi.nlm.nih.gov/32813232

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis

Autor: Atul Deodhar, Lianne S. Gensler, Joachim Sieper, Michael Clark, Cesar Calderon, Yuhua Wang, Yiying Zhou, Jocelyn H. Leu, Kim Campbell, Kristen Sweet, Diane D. Harrison, Elizabeth C. Hsia, Désirée Heijde, Frederico Ariel, Cecilia Adma Asnal, Alberto Berman, Gustavo Citera, Graciela Rodriguez, Veronica Gabriela Savio, Paul Bird, Hedley Griffiths, David Nicholls, Maureen Rischmueller, Jane Zochling, Kurt De Vlam, Michel Malaise, Adrien Nzeusseu Toukap, Filip Van den Bosch, Johan Vanhoof, Rubens Bonfiglioli, Mauro Keiserman, Antonio Scafuto Scotton, Ricardo Xavier, Antonio Carlos Ximenes, Assen Atanasov, Ivan Goranov, Ivan Kazmin, Rodina Nestorova Licheva, Nikolay Nikolov, Boycho Oparanov, Rumen Stoilov, Louis Bessette, Jude Rodrigues, Ladislav Bortilik, Eva Dokoupilova, Zdenek Dvoarak, Dagmar Galatikova, Petr Nemec, Lucie Podrazilova, Gabriela Simkova, Zuzana Stejfova, Radka Moravcova, Petr Vitek, Alain Cantagrel, Athan Baillet, Beatrice Banneville, Bernard Combe, Maxime Breban, Minh Nguyen, Philippe Goupille, Juergen Braun, Andrea Everding, Joern Kekow, Ramona Koenig, Andrea Rubbert‐Roth, Torsten Witte, Attila Bartha, Edit Drescher, Kata Kerekes, Attila Kovacs, Judit Pulai, Bernadette Rojkovich, Sandor Szanto, Edit Toth, Hilario Avila, Igancio Garcia Torre, Fedra Irazoque, Marco Maradiaga, Cesar Pacheco, Marek Brzosko, Anna Dudek, Slawomir Jeka, Marek Krogulec, Brygida Kwiatkowska, Piotr Wiland, Rafal Wojciechowski, Agnieszka Zielinska, Helena Santos, Olga Bugrova, Valery Christyakov, Vladimir Gorbunov, Elena Ilivanova, Elena Zemerova, Rima Kamalova, Tatyana Kameneva, Galina Macievskaya, Irina Marusenko, Alexey Maslyansky, Svetlana Myasoedova, Leisan Myasoutova, Boris Nemtsov, Olga Nesmeyanova, Tatyana Plaksina, Tatyana Pokrovskaya, Svetlana Polyakova, Andrey Rebrov, Liudmila Savina, Svetlana Smakotina, Marina Stanislav, Olga Ukhanova, Irina Vinogradova, Elena Zonova, Han Joo Baek, Tae‐Hwan Kim, ChangKeun Lee, SangHeon Lee, Sang‐Hoon Lee, Shin‐Seok Lee, Sung‐Hwan Park, YeongWook Song, Chang‐Hee Suh, Juan Amarelo Ramos, Franciso Javier Blanco, Eduardo Collantes, Miguel Consuelo Diaz, Maria Luz Garcia Vivar, Jordi Gratacos, Xavier Juanola, Der‐Yuan Chen, Hsiang‐Cheng Chen, Kun‐Hung Chen, Ying‐Chou Chen, Ying‐Ming Chiu, Shue‐Fen Luo, Shih‐Tzu Tsai, Jui‐Cheng Tseng, Cheng‐Chung Wei, Meng‐Yu Weng, Orest Abrahamovych, Dmytro Reshotko, Oleksandr Golovchenko, Ihor Hospodarsky, Oleg Iaremenko, Olena Levchenko, Oleksandr Dudnyk, Olena Garmish, Olena Grishyna, Galyna Protsenko, Dmytro Rekalov, Svitlana Smiyan, Mykola Stanislavchuk, Svitlana Trypilka, Vira Tseluyko, Samvel Turianytsia, Viktoriya Vasylets, Nataliya Virstyuk, Yaroslav Kleban, Coziana Ciurtin, Karl Gaffney, Wiranthi Gunasekera, Kirsten Mackay, Jon Packham, Raj Sengupta, Hasan Tahir, Jacob Aelion, Ralph Bennett, Julio Gonzalez‐Paoli, Robert M. Griffin, Michael Grisanti, Jyothi Mallepalli, Eric Peters, Joy Schechtman, Atul Singhal

Publikováno v: Arthritis and Rheumatology, 71(2), 258-270. WILEY
Deodhar, A; Gensler, LS; Sieper, J; Clark, M; Calderon, C; Wang, Y; et al.(2018). Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.. Arthritis & rheumatology (Hoboken, N.J.). doi: 10.1002/art.40728. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3x5990zb
Arthritis & rheumatology (Hoboken, N.J.), vol 71, iss 2

Author(s): Deodhar, Atul; Gensler, Lianne S; Sieper, Joachim; Clark, Michael; Calderon, Cesar; Wang, Yuhua; Zhou, Yiying; Leu, Jocelyn H; Campbell, Kim; Sweet, Kristen; Harrison, Diane D; Hsia, Elizabeth C; van der Heijde, Desiree | Abstract: Objecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f232b4efcd4d46d6ba1ded5ac5cc76d0
https://doi.org/10.1002/art.40728

Inducing a Transient Increase in Blood-Brain Barrier Permeability for Improved Liposomal Drug Therapy of Glioblastoma Multiforme

Autor: Chia-Hsin Hsu, Jen-Hao Lin, Yu-Wen Tien, Patrick C.H. Hsieh, David J. Lundy, Kun-Hung Chen, I-Chia Peng, Keng-Jung Lee

Publikováno v: ACS nano. 13(1)

The blood-brain barrier (BBB) selectively controls the passage of endogenous and exogenous molecules between systemic circulation and the brain parenchyma. Nanocarrier-based drugs such as liposomes and nanoparticles are an attractive prospect for can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9e4413b473d662db7adbf8aa01ccdd
https://pubmed.ncbi.nlm.nih.gov/30532951

Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific

Autor: Patrick S. Stayton, Chien-Hsi Chen, Peilin Chen, Kun-Hung Chen, James J. Lai, Patrick C.H. Hsieh, David J. Lundy, E. K.-W. Toh, C. Shih, Huan-Cheng Chang, A. S. Hoffman

Publikováno v: Nanoscale. 7:15863-15872

This study comprehensively investigates the changing biodistribution of fluorescent-labelled polystyrene latex bead nanoparticles in a mouse model of inflammation. Since inflammation alters systemic circulatory properties, increases vessel permeabili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0bbac5fec76803d75be24c57fd0a6d
https://doi.org/10.1039/c5nr03626g

Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery

Autor: Nicholas Dunne, Grace Cole, Helen O. McCarthy, Aleksey Zholobenko, Tracy Robson, Victoria Kett, Joanne McCaffrey, Ahlam A. Ali, Kun-Hung Chen, John W. McBride, Cian M. McCrudden, Stephen P. Loughran, Ashley S. Massey, Ryan F. Donnelly, Sreekanth Pentlavalli

Publikováno v: Journal of Controlled Release. 189:141-149

The design of a non-viral gene delivery vehicle capable of delivering and releasing a functional nucleic acid cargo intracellularly remains a formidable challenge. For systemic gene therapy to be successful a delivery vehicle is required that protect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add243508423bf6f447f9e632e5f4818
https://doi.org/10.1016/j.jconrel.2014.06.048