Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Kun‐Ju Lin"'
Publikováno v:
Brain and Behavior, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Major depressive disorder (MDD) is characterized by hippocampal volume reduction, impacting cognitive function. Inflammation, particularly elevated tumor necrosis factor‐alpha (TNF‐α) levels, is consistently implicated in MDD
Externí odkaz:
https://doaj.org/article/5b12e810837344b5b494e2ee1c750042
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background Tau pathology plays a crucial role in neurodegeneration diseases including Alzheimer’s disease (AD) and non-AD diseases such as progressive supranuclear palsy. Tau positron emission tomography (PET) is an in-vivo and non-invasiv
Externí odkaz:
https://doaj.org/article/14ab9a90087a4f04b6bf21abdc2153b6
Autor:
Hsin-I Chang, Kuo-Lun Huang, Chung-Gue Huang, Chi-Wei Huang, Shu-Hua Huang, Kun-Ju Lin, Chiung-Chih Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5607 (2024)
The purpose of this study was to investigate whether plasma biomarkers can help to diagnose, differentiate from Alzheimer disease (AD), and stage cognitive performance in patients with positron emission tomography (PET)-confirmed primary age-related
Externí odkaz:
https://doaj.org/article/6b6dfc707bec468aa9d27e03d2999798
Autor:
Kuan-Yi Wu, Kun-Ju Lin, Chia-Hsiang Chen, Chia-Yih Liu, Yi-Ming Wu, Tzu-Chen Yen, Ing-Tsung Hsiao
Publikováno v:
Biomedical Journal, Vol 46, Iss 6, Pp 100589- (2023)
Background: A substantial proportion of individuals with late-life major depression could be classified as having a suspected non-Alzheimer disease pathophysiology (SNAP), as indicated by a negative test for the biomarker β-amyloid (Aβ-) but a posi
Externí odkaz:
https://doaj.org/article/5a31263845744a48afd307b9a2f92c90
Autor:
Yu-Ching Ni, Zhi-Kun Lin, Chen-Han Cheng, Ming-Chyi Pai, Pai-Yi Chiu, Chiung-Chih Chang, Ya-Ting Chang, Guang-Uei Hung, Kun-Ju Lin, Ing-Tsung Hsiao, Chia-Yu Lin, Hui-Chieh Yang
Publikováno v:
Diagnostics, Vol 14, Iss 4, p 365 (2024)
Alzheimer’s disease (AD) and vascular dementia (VaD) are the two most common forms of dementia. However, their neuropsychological and pathological features often overlap, making it difficult to distinguish between AD and VaD. In addition to clinica
Externí odkaz:
https://doaj.org/article/1d3bd36bcfdf46169e02ce387203a5ae
Autor:
Huan-Chun Lin, Kun-Ju Lin, Kuo-Lun Huang, Shih-Hsin Chen, Tsung-Ying Ho, Chin-Chang Huang, Jung-Lung Hsu, Chiung-Chih Chang, Ing-Tsung Hsiao
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionTau-targeted positron emission tomography (tau-PET) is a potential tool for the differential diagnosis of Alzheimer’s disease (AD) and to clarify the distribution of tau deposition. In addition to the quantitative analysis of tau-PET sc
Externí odkaz:
https://doaj.org/article/bd647fd6e9c948a7a7636aa56c36b6e8
Autor:
Kuan-Yi Wu, Kun-Ju Lin, Chia-Hsiang Chen, Chia-Yih Liu, Yi-Ming Wu, Cheng-Sheng Chen, Tzu-Chen Yen, Ing-Tsung Hsiao
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Cerebral amyloid-β (Aβ) depositions in depression in old age are controversial. A substantial proportion of individuals with late-life major depressive disorder (MDD) could be classified as having suspected non-Alzheimer’s disease pathophysiology
Externí odkaz:
https://doaj.org/article/068b28571faa46b49fc28ecb679ccb7c
Autor:
Rajat Subhra Karmakar, Jer-Chyi Wang, Yu-Ting Huang, Kun-Ju Lin, Kuo-Chen Wei, Yung-Hsin Hsu, Ying-Cheng Huang, Yu-Jen Lu
Publikováno v:
ACS Omega, Vol 5, Iss 45, Pp 29342-29350 (2020)
Externí odkaz:
https://doaj.org/article/b4ee63dde0f4419fa05f4423f4886431
Autor:
Kuo-Lun Huang, Ing-Tsung Hsiao, Meng-Yang Ho, Jung-Lung Hsu, Yeu-Jhy Chang, Ting-Yu Chang, Chi-Hung Liu, Chien-Hung Chang, Yi-Ming Wu, Kuan-Yi Wu, Shiaw-Pyng Wey, Tzu-Chen Yen, Nobuyuki Okamura, Tsong-Hai Lee, Kun-Ju Lin
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background The aim of this study is to investigate the associations between post-stroke cognitive impairment (PSCI) severity and reactive astrogliosis (RA) extent on normalized 18F-THK-5351 positron-emission tomography (PET) imaging in amylo
Externí odkaz:
https://doaj.org/article/a4b94809a3b8419d862514aeb19803e7
Autor:
Szu-Ying Lin, Kun-Ju Lin, Po-Chen Lin, Chin-Chang Huang, Chiung-Chih Chang, Yi-Chung Lee, Ing-Tsung Hsiao, Tzu-Chen Yen, Wen-Sheng Huang, Bang-Hung Yang, Pei-Ning Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-10 (2019)
Abstract Introduction Due to the high cost and high failure rate of ascertaining amyloid positron emission tomography positivity (PET+) in patients with earlier stage Alzheimer’s disease (AD), an effective pre-screening tool for amyloid PET scans i
Externí odkaz:
https://doaj.org/article/cc7a9ec23b614bd59c2c2ecb79519bc9