Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kumud R. Poudel"'
Autor:
Haritha Mathsyaraja, Jonathen Catchpole, Brian Freie, Emily Eastwood, Ekaterina Babaeva, Michael Geuenich, Pei Feng Cheng, Jessica Ayers, Ming Yu, Nan Wu, Sitapriya Moorthi, Kumud R Poudel, Amanda Koehne, William Grady, A McGarry Houghton, Alice H Berger, Yuzuru Shiio, David MacPherson, Robert N Eisenman
Publikováno v:
eLife, Vol 10 (2021)
MGA, a transcription factor and member of the MYC network, is mutated or deleted in a broad spectrum of malignancies. As a critical test of a tumor suppressive role, we inactivated Mga in two mouse models of non-small cell lung cancer using a CRISPR-
Externí odkaz:
https://doaj.org/article/e444f5d17b9d4890b2bf40c9a7a0bd54
Autor:
Brian Freie, Michael Geuenich, Alice H. Berger, Nan Wu, Sitapriya Moorthi, Jessica Ayers, A. McGarry Houghton, Ekaterina Babaeva, Pei Feng Cheng, Robert N. Eisenman, Ming Yu, Kumud R. Poudel, Yuzuru Shiio, Emily Eastwood, Amanda Koehne, William M. Grady, Jonathen Catchpole, Haritha Mathsyaraja, David MacPherson
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
MGA, a transcription factor and member of the MYC network, is mutated or deleted in a broad spectrum of malignancies. As a critical test of a tumor suppressive role, we inactivated Mga in two mouse models of non-small cell lung cancer using a CRISPR-
Autor:
Jonathen Catchpole, Jessica Ayers, Pei Feng Cheng, Nan Wu, William M. Grady, Haritha Mathsyaraja, Brian Freie, Amanda Koehne, Kumud R. Poudel, Sitapriya Moorthi, Alice H. Berger, Yuzuru Shiio, David MacPherson, Ming Yu, Michael Geuenich, A. McGarry Houghton, Emily Eastwood, Robert N. Eisenman, Ekaterina Babaeva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed67f264991248f94142dd25489d0398
https://doi.org/10.7554/elife.64212.sa2
https://doi.org/10.7554/elife.64212.sa2
Autor:
Ekaterina Babaeva, Kumud R. Poudel, David MacPherson, Emily Eastwood, Brian Freie, Yuzuru Shiio, Jonathen Catchpole, Haritha Mathsyaraja, Jessica Ayers, Amanda Koehne, William M. Grady, Pei Feng Cheng, A. McGarry Houghton, Michael Geuenich, Nan Wu, Ming Yu, Robert N. Eisenman
MGA, a transcription factor and member of the MYC network, is mutated or deleted in a broad spectrum of malignancies. As a critical test of a tumor suppressive role, we inactivated Mga in two mouse models of non-small cell lung cancer using a CRISPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a1f45ec3e3d34feadd724ebb09d622
https://doi.org/10.1101/2020.10.16.334714
https://doi.org/10.1101/2020.10.16.334714
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995110
The purpose of this chapter is to serve as a guide for those who wish to carry out experiments tracking single proteins in planar supported biomimetic membranes. This chapter describes, in detail, the construction of a simple single molecule microsco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d673e28301d04b07a45519b2fa0eb46d
https://doi.org/10.1007/978-1-4939-9512-7_17
https://doi.org/10.1007/978-1-4939-9512-7_17
Autor:
Allen Su, William M. Grady, Cecilia B. Moens, Haritha Mathsyaraja, Maralice Conacci-Sorrell, Robert N. Eisenman, Sarah Anderson, Minna Roh-Johnson, Kumud R. Poudel, Jihong Bai, Thuong Ho
Publikováno v:
Developmental cell. 45(6)
Normal cells acquire aggressive behavior by modifying signaling pathways. For instance, alteration of endocytosis profoundly impacts both proliferation and migration during tumorigenesis. Here we investigate the mechanisms that enable the endocytic m
Autor:
Kumud R. Poudel, Jihong Bai
Publikováno v:
Current Opinion in Cell Biology. 26:28-33
Synaptic vesicles (SVs) are the repositories of neurotransmitters. They are locally recycled at nerve terminals following exocytosis. A unique feature of these vesicles is the uniformity of their morphology, which is well maintained even after rounds
Autor:
Minna Roh-Johnson, Thomas Brabletz, Sarah Anderson, Kumud R. Poudel, Ming Yu, Maralice Conacci-Sorrell, Robert N. Eisenman, Cecilia B. Moens, Jihong Bai, Nofit Borenstein-Auerbach, William N. Grady
Publikováno v:
Proceedings of the National Academy of Sciences. 113
MYC-nick is a cytoplasmic, transcriptionally inactive member of the MYC oncoprotein family, generated by a proteolytic cleavage of full-length MYC. MYC-nick promotes migration and survival of cells in response to chemotherapeutic agents or withdrawal
Autor:
Hang Yu, Kumud R. Poudel, Yan Liu, Klaus Schulten, Thuong Ho, Yongming Dong, Allen Su, Jihong Bai
Publikováno v:
Molecular Biology of the Cell
Endophilin is a founding member of the membrane-bending protein family. It promotes rapid endocytosis on a milliseconds-to-seconds time scale. The short duration of rapid endocytosis requires endophilin to act quickly. High-resolution kinetic measure
Publikováno v:
Biophysical Journal. 112:326a-327a
Time is a limiting factor for many cellular processes. Neurons are particularly sensitive to time as they are specialized for rapid communication. For instance, synaptic vesicle endocytosis could occur within 50 milliseconds to recycle vesicle membra