Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kumju Youn"'
Publikováno v:
Marine Drugs, Vol 21, Iss 11, p 580 (2023)
Marine polyphenols, including eckol(EK), dieckol(DK), and 8,8’-bieckol(BK), have attracted attention as bioactive ingredients for preventing Alzheimer’s disease (AD). Since AD is a multifactorial disorder, the present study aims to provide an unb
Externí odkaz:
https://doaj.org/article/3999030b5b624375aa289eaa78e82cd2
Publikováno v:
Food Science and Human Wellness, Vol 11, Iss 3, Pp 483-493 (2022)
ABSTRACT: Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by cognitive decline and memory impairment. Many lines of evidence indicate that excessive β-amyloid peptide (Aβ) generation and aggregation play pivota
Externí odkaz:
https://doaj.org/article/3fd9ec33e25d4c46ad748f3b8dfcb29d
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 629 (2023)
Increasing evidence is suggesting that amyloid-β peptide (Aβ), a characteristic of Alzheimer’s disease (AD), induces oxidative stress and mitochondrial dysfunction, leading to neuronal death. This study aimed to demonstrate the antioxidant and an
Externí odkaz:
https://doaj.org/article/995e33b5917048b0a223ab73ba2c773d
Autor:
Eunbi Cho, Kumju Youn, Huiyoung Kwon, Jieun Jeon, Wan-Seob Cho, Se Jin Park, Seung Hwan Son, Dae Sik Jang, Chan Young Shin, Minho Moon, Mira Jun, Nam-Jung Kim, Dong Hyun Kim
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112763- (2022)
Alzheimer’s disease (AD) is caused by various pathological mechanisms; therefore, it is necessary to develop drugs that simultaneously act on multiple targets. In this study, we investigated the effects of eugenitol, which has anti-amyloid β (Aβ)
Externí odkaz:
https://doaj.org/article/0d0b2c4c58944feb914eedbb8f70c7a7
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 147, Iss , Pp 112651- (2022)
Abnormal melanin synthesis upon UV exposure causes excessive oxidative stress, which leads to skin hyperpigmentation disorders such as freckles, melisma, and age spots. The present study investigated the anti-melanogenic effects of decursin and the u
Externí odkaz:
https://doaj.org/article/51e36de97ce9466a95b68ca1bc838eeb
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112271- (2021)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory loss and cognitive impairment. β-Amyloid (Aβ) is widely accepted as the main neurotoxin that triggers mitochondrial-associated oxidative stress, leading t
Externí odkaz:
https://doaj.org/article/052f471640c14923ba60954d961471a2
Publikováno v:
Nutrients, Vol 14, Iss 18, p 3713 (2022)
Melanogenesis is the process of melanin synthesis to protect the skin against ultraviolet radiation and other external stresses. The loss of skin pigmentation is closely related to depigmented skin disorders. The melanogenic effects of pinostrobin, a
Externí odkaz:
https://doaj.org/article/a8cf625c3ca4465ab22241aea750d9a2
Publikováno v:
Journal of Functional Foods, Vol 42, Iss , Pp 30-37 (2018)
Beta-amyloid (Aβ) are known to form senile plaques causing neuroinflammation, which was accepted as the major pathological mechanism in Alzheimer’s disease (AD). To elucidate the molecular mechanism of gamma-linolenic acid (GLA) on neuroprotective
Externí odkaz:
https://doaj.org/article/8e32a164405949c698f428ce1ea9fc8e
Autor:
Jeong-Hyun Yoon, Nayoung Lee, Kumju Youn, Mi Ra Jo, Hyeung-Rak Kim, Dong-Seok Lee, Chi-Tang Ho, Mira Jun
Publikováno v:
Marine Drugs, Vol 19, Iss 3, p 152 (2021)
The proteolytic processing of amyloid precursor protein (APP) by β-secretase (BACE1) and γ-secretase releases amyloid-β peptide (Aβ), which deposits in amyloid plaques and contributes to the initial causative events of Alzheimer’s disease (AD).
Externí odkaz:
https://doaj.org/article/83f16eda2d594e1c8e8f329b8f59be06
Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches
Publikováno v:
Nutrients, Vol 13, Iss 1, p 254 (2021)
Alzheimer’s disease (AD) is a neurodegenerative disease conceptualized as a clinical-biological neurodegenerative construct where amyloid-beta pathophysiology is supposed to play a role. The loss of cognitive functions is mostly characterized by th
Externí odkaz:
https://doaj.org/article/b0dd17bbbbbb43449c0fab84ca2c4f74