Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kumiko Yoshizawa-Kumagaye"'
Autor:
Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Kensaku Kasuga, Ayano Kimura, Koichi Moteki, Ruriko Abe, Shungo Adachi, Shoich Kinoshita, Kumiko Yoshizawa‐Kumagaye, Hideki Nishio, Takashi Saito, Takaomi C Saido, Tohru Yamamoto, Masaki Nishimura, Hidenori Taru, Yuriko Sobu, Hiroyuki Ohba, Shingo Nishiyama, Norihiro Harada, Takeshi Ikeuchi, Hideo Tsukada, Yasuomi Ouchi, Toshiharu Suzuki
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-15 (2023)
Abstract We propose a new therapeutic strategy for Alzheimer's disease (AD). Brain peptide p3‐Alcβ37 is generated from the neuronal protein alcadein β through cleavage of γ‐secretase, similar to the generation of amyloid β (Aβ) derived from
Externí odkaz:
https://doaj.org/article/069ea382ed2549839af4f297856b8dfc
Autor:
Kaoru Nomura, Shoko Mori, Kohki Fujikawa, Tsukiho Osawa, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Takao Yoda, Masafumi Shionyu, Tsuyoshi Shirai, Ken-ichi Nishiyama, Keiko Shimamoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Non-proteinaceous components in membranes regulate membrane protein insertion cooperatively with proteinaceous translocons. An endogenous glycolipid in the Escherichia coli membrane called membrane protein integrase (MPIase) is one such comp
Externí odkaz:
https://doaj.org/article/c4b649d714414d0ba65ed930bfcd743a
Autor:
Goro Miki, Nobuko Kuroishi, Mariko Tokashiki, Sayaka Nagata, Masaji Tamura, Taku Yoshiya, Kumiko Yoshizawa-Kumagaye, Shinya Ashizuka, Joji Kato, Motoo Yamasaki, Kazuo Kitamura
Publikováno v:
Gastrointestinal Disorders, Vol 2, Iss 4, Pp 366-377 (2020)
Human adrenomedullin (AM), a hypotensive peptide, also has anti-colitis activity. We prepared a polyethylene glycol (PEG) ylated form of AM through the conjugation of PEG-AM (1–15) and AM (15–52). Highly pure monomeric 20 kDa PEG-AM (20kPEG-AM) s
Externí odkaz:
https://doaj.org/article/ac77b156f55c4ae7ad234f929d46d344
Autor:
Takafumi Minato, Satoru Nirasawa, Teruki Sato, Tomokazu Yamaguchi, Midori Hoshizaki, Tadakatsu Inagaki, Kazuhiko Nakahara, Tadashi Yoshihashi, Ryo Ozawa, Saki Yokota, Miyuki Natsui, Souichi Koyota, Taku Yoshiya, Kumiko Yoshizawa-Kumagaye, Satoru Motoyama, Takeshi Gotoh, Yoshikazu Nakaoka, Josef M. Penninger, Hiroyuki Watanabe, Yumiko Imai, Saori Takahashi, Keiji Kuba
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The enzyme ACE2 is involved in cardiac pathology and can counteract heart failure and other cardio-pulmonary diseases. Here the authors show that bacteria produce an ACE2-like enzyme that is effective in suppressing cardiac hypertrophy and fibrosis i
Externí odkaz:
https://doaj.org/article/d26136e7b956463b9d355114f88c8f40
Autor:
Shoko Mori, Kaoru Nomura, Kohki Fujikawa, Tsukiho Osawa, Masafumi Shionyu, Takao Yoda, Tsuyoshi Shirai, Shugo Tsuda, Kumiko Yoshizawa-Kumagaye, Shun Masuda, Hideki Nishio, Taku Yoshiya, Sonomi Suzuki, Maki Muramoto, Ken-ichi Nishiyama, Keiko Shimamoto
Publikováno v:
ACS Chemical Biology. 17:609-618
Inducing newly synthesized proteins to appropriate locations is an indispensable biological function in every organism. Integration of proteins into biomembranes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76476ae3dd084adb03b9ddedea7d973
https://doi.org/10.1021/acschembio.1c00882
https://doi.org/10.1021/acschembio.1c00882
Autor:
Sayaka Nagata, Masaji Tamura, Kumiko Yoshizawa-Kumagaye, Joji Kato, Mariko Tokashiki, Goro Miki, Taku Yoshiya, Kazuo Kitamura, Shinya Ashizuka, Nobuko Kuroishi, Motoo Yamasaki
Publikováno v:
Gastrointestinal Disorders, Vol 2, Iss 33, Pp 366-377 (2020)
Gastrointestinal Disorders
Volume 2
Issue 4
Pages 33-377
Gastrointestinal Disorders
Volume 2
Issue 4
Pages 33-377
Human adrenomedullin (AM), a hypotensive peptide, also has anti-colitis activity. We prepared a polyethylene glycol (PEG) ylated form of AM through the conjugation of PEG-AM (1&ndash
15) and AM (15&ndash
52). Highly pure monomeric 20 kDa PE
15) and AM (15&ndash
52). Highly pure monomeric 20 kDa PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6e8736c9161d345457f1c75bf4250d
https://www.mdpi.com/2624-5647/2/4/33
https://www.mdpi.com/2624-5647/2/4/33
Autor:
Saori Takahashi, Takafumi Minato, Yumiko Imai, Keiji Kuba, Tadashi Yoshihashi, Yoshikazu Nakaoka, Midori Hoshizaki, Teruki Sato, Hiroyuki Watanabe, Satoru Nirasawa, Tadakatsu Inagaki, Kazuhiko Nakahara, Takeshi Gotoh, Josef M. Penninger, Taku Yoshiya, Satoru Motoyama, Saki Yokota, Miyuki Natsui, Tomokazu Yamaguchi, Kumiko Yoshizawa-Kumagaye, Ryo Ozawa, Souichi Koyota
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11:1058
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11:1058
Angiotensin-converting enzyme 2 (ACE2) is critically involved in cardiovascular physiology and pathology, and is currently clinically evaluated to treat acute lung failure. Here we show that the B38-CAP, a carboxypeptidase derived from Paenibacillus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a27ba1f20feb9d9f066ab5a99265ad
Autor:
Shinya Oishi, Taku Yoshiya, Shugo Tsuda, Hideki Nishio, Kumiko Yoshizawa-Kumagaye, Hiroyuki Ishiba, Masayoshi Mochizuki
Publikováno v:
Angewandte Chemie. 130:2127-2131
A solubilizing Trt-K10 tag was developed for the effective chemical preparation of peptides/proteins with low solubility. The Trt-K10 tag comprises a hydrophilic oligo-Lys sequence and a trityl anchor, and can be selectively introduced to a side chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8cc414d6b7c4e63c2948c27a295cc6
https://doi.org/10.1002/ange.201711546
https://doi.org/10.1002/ange.201711546
Autor:
Yoshihisa, Ueno, Kumiko, Yoshizawa-Kumagaye, Junji, Emura, Tomoko, Urabe, Taku, Yoshiya, Tsuyoshi, Furumoto, Katsura, Izui
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2072
Phosphoenolpyruvate carboxylases (PEPCs), mostly known as the enzymes responsible for the initial CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e2beaa9cd80b4e1671817c522d7788e
https://pubmed.ncbi.nlm.nih.gov/31541450
https://pubmed.ncbi.nlm.nih.gov/31541450
Autor:
Taku Yoshiya, Kumiko Yoshizawa-Kumagaye, Tsuyoshi Furumoto, Junji Emura, Yoshihisa Ueno, Tomoko Urabe, Katsura Izui
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998647
Phosphoenolpyruvate carboxylases (PEPCs), mostly known as the enzymes responsible for the initial CO2 fixation during C4 photosynthesis, are regulated by reversible phosphorylation in vascular plants. The phosphorylation site on a PEPC molecule is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40386d006e9f017bf275ec773d3209f1
https://doi.org/10.1007/978-1-4939-9865-4_18
https://doi.org/10.1007/978-1-4939-9865-4_18
