Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kumiko Suyama"'
Autor:
Nami Masumoto, Shingo Kato, Masahiro Aichi, Sho Hasegawa, Kota Sahara, Kumiko Suyama, Akane Sano, Tomoyuki Miyazaki, Koji Okudela, Takeshi Kaneko, Takuya Takahashi
Publikováno v:
Thoracic Cancer, Vol 14, Iss 29, Pp 2897-2908 (2023)
Abstract Background Small cell lung cancer (SCLC) is a neuroendocrine tumor with poor prognosis. Neuroendocrine tumors possess characteristics of both nerve cells and hormone‐secreting cells; therefore, targeting the neuronal properties of these tu
Externí odkaz:
https://doaj.org/article/418c4c541dbf4c5191c29bc5273bfa0b
Autor:
Hirobumi Tada, Tomoyuki Miyazaki, Kiwamu Takemoto, Susumu Jitsuki, Waki Nakajima, Mayu Koide, Naoko Yamamoto, Akiko Taguchi, Honami Kawai, Kasane Komiya, Kumiko Suyama, Hiroki Abe, Akane Sano, Takuya Takahashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Exposure to a stressful environment early in life can cause psychiatric disorders by disrupting circuit formation. Actin plays central roles in regulating neuronal structure and protein trafficking. We have recently reported that neonatal is
Externí odkaz:
https://doaj.org/article/febcb8090736488ca072289b8a580921
Autor:
Hirobumi Tada, Mayu Koide, Wakana Ara, Yusuke Shibata, Toshiya Funabashi, Kumiko Suyama, Takahisa Goto, Takuya Takahashi
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131359 (2015)
Cognitive function can be affected by the estrous cycle. However, the effect of the estrous cycle on synaptic functions is poorly understood. Here we show that in female rats, inhibitory-avoidance (IA) task (hippocampus-dependent contextual fear-lear
Externí odkaz:
https://doaj.org/article/eee1ff05b6344897a5d574cd1896bc07
Autor:
Tetsu Arisawa, Takuya Takahashi, Tomoyuki Miyazaki, Wataru Ota, Kumiko Suyama, Akane Sano, Yuuki Takada
Publikováno v:
Neuroscience Research. 173:106-113
The glutamate α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) is an important molecule in neurotransmission. We have recently developed the first positron emission tomography (PET) tracer [11C]K-2 to visualize and quantify A
Autor:
Takao Hamakubo, Hirobumi Tada, Akane Sano, Kiwamu Takemoto, Kumiko Suyama, Takeharu Nagai, Hiroko Iwanari, Takuya Takahashi
Publikováno v:
Nature Biotechnology. 35:38-47
Development of an optical method to inactivate synaptic receptors in mice with temporal precision will enable a better understanding of their roles in cognition. The synaptic delivery of neurotransmitter receptors, such as GluA1 AMPA (α-amino-3-hydr
Autor:
Honami Kawai, Waki Nakajima, Kiwamu Takemoto, Akane Sano, Kasane Komiya, Akiko Taguchi, Hiroki Abe, Susumu Jitsuki, Takuya Takahashi, Naoko Yamamoto, Hirobumi Tada, Kumiko Suyama, Mayu Koide, Tomoyuki Miyazaki
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Exposure to a stressful environment early in life can cause psychiatric disorders by disrupting circuit formation. Actin plays central roles in regulating neuronal structure and protein trafficking. We have recently reported that neonatal isolation i
Autor:
Yoshio Goshima, Noriyuki Higo, Tomohiro Okuda, Yuki Katsuno, Nobuyuki Mochizuki, Kumiko Suyama, Takashi Komori, Hiroki Abe, Akane Sano, Waki Nakajima, Hirobumi Tada, Aoi Jitsuki-Takahashi, Takuya Takahashi, Hitoshi Masuyama, Yumi Murata, Susumu Jitsuki
Publikováno v:
Science (New York, N.Y.). 360(6384)
A small molecule for stroke therapy Better therapies for motor impairments after stroke are greatly needed. In mice and nonhuman primates, Abe et al. found that edonerpic maleate enhanced synaptic plasticity and functional recovery after a traumatic
Autor:
Yoko Kuroki, Dai Mitsushima, Toshiya Funabashi, Anne M. Etgen, Yoshinori Kamiya, Kumiko Suyama, Akane Sano, Takuya Takahashi, Hirobumi Tada, Takahisa Goto
Publikováno v:
Neuroscience. 248:664-669
Reproductive success depends on a robust and appropriately timed preovulatory luteinizing hormone (LH) surge, which is induced by the activation of gonadotropin-releasing hormone (GnRH) neurons in response to positive feedback from increasing estroge
Autor:
Mayu Koide, Kiwamu Takemoto, Susumu Jitsuki, Kenkichi Takase, Naoko Yamamoto, Kumiko Suyama, Waki Nakajima, Takuya Takahashi, Akane Sano, Hirobumi Tada, Kasane Komiya, Tomoyuki Miyazaki, Akiko Taguchi
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Social separation early in life can lead to the development of impaired interpersonal relationships and profound social disorders. However, the underlying cellular and molecular mechanisms involved are largely unknown. Here, we found that isolation o
Autor:
Mayu Koide, Toshiya Funabashi, Wakana Ara, Kumiko Suyama, Takuya Takahashi, Takahisa Goto, Yusuke Shibata, Hirobumi Tada
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131359 (2015)
PLoS ONE
PLoS ONE
Cognitive function can be affected by the estrous cycle. However, the effect of the estrous cycle on synaptic functions is poorly understood. Here we show that in female rats, inhibitory-avoidance (IA) task (hippocampus-dependent contextual fear-lear